The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics

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The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1007242739
P356DOI10.1038/NI1534
P698PubMed publication ID18037890
P5875ResearchGate publication ID5809627

P50authorJonathan BrombergQ89707593
Yaozhong DingQ89961217
Edward H SchuchmanQ92756224
Levi G LedgerwoodQ116793180
Girdhari LalQ47415617
Jordi OchandoQ48546528
Florent GinhouxQ57369307
Miriam MeradQ64748184
P2093author name stringNan Zhang
Sergio A Lira
Yu Yang
Xingxuan He
Maria L Allende
Alexandre Garin
Helene Peche
Steven J Esses
P2860cites workSpatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesionQ24299123
Transfection of IL-10 expression vectors into endothelial cultures attenuates alpha4beta7-dependent lymphocyte adhesion mediated by MAdCAM-1Q24805188
Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphaticsQ28268587
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migrationQ28512928
Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigrationQ28592508
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organsQ28594485
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonistsQ29618071
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1Q29619644
Targeting mucosal addressin cellular adhesion molecule (MAdCAM)-1 to noninvasively image experimental Crohn's diseaseQ30439177
Immunoelectron microscopic study of PECAM-1 expression on lymphatic endothelium of the human tongueQ30692279
Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectorsQ31036743
Dendritic-cell trafficking to lymph nodes through lymphatic vesselsQ33989067
Regulation of ICAM-1 mRNA stability by cycloheximide: role of serine/threonine phosphorylation and protein synthesisQ71750659
The transcellular railway: insights into leukocyte diapedesisQ82437296
Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineagesQ34091556
Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.Q34227743
Lymphocyte trafficking across high endothelial venules: dogmas and enigmasQ35762431
Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivoQ35809985
An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endotheliumQ36228128
Impaired primary T cell responses in L-selectin-deficient miceQ36366190
Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transitQ36402627
Transcriptomal comparison of human dermal lymphatic endothelial cells ex vivo and in vitroQ38305668
Generation and characterization of a mouse lymphatic endothelial cell line.Q40305468
Vimentin function in lymphocyte adhesion and transcellular migrationQ40326248
Isolation and characterization of a novel mouse lymphatic endothelial cell line: SV-LEC.Q40367765
Inhibition of alpha7-nicotinic acetylcholine receptor expression by arsenite in the vascular endothelial cellsQ40408525
Simultaneous quantitative analysis of ceramide and sphingosine in mouse blood by naphthalene-2,3-dicarboxyaldehyde derivatization after hydrolysis with ceramidaseQ40433898
LDL transcytosis by protein membrane diffusion.Q40605516
The immune modulator FTY720 targets sphingosine 1-phosphate receptorsQ40736684
Structural characterization of the mouse Foxf1a geneQ40811358
Endothelial antigen presentation: stimulation of previously activated but not naïve TCR-transgenic mouse T cellsQ41005295
Heat shock-induced cell death in murine microvascular endothelial cells depends on priming with tumor necrosis factor-alpha or interferon-gammaQ41433626
Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissuesQ41764860
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flowQ41789594
Sphingosine-1-phosphate receptor subtype-specific positive and negative regulation of Rac and haematogenous metastasis of melanoma cellsQ42157097
Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domainsQ42489783
DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migrationQ42496763
Naive and memory T cells show distinct pathways of lymphocyte recirculationQ42937583
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinusesQ43746398
The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptorsQ44722923
Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rateQ44734550
Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphateQ46494392
Sphingosine 1-phosphate receptors regulate chemokine-driven transendothelial migration of lymph node but not splenic T cells.Q46664082
Enhanced FTY720-mediated lymphocyte homing requires G alpha i signaling and depends on beta 2 and beta 7 integrinQ46902176
Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathwayQ48534206
Regulation of Homeostatic Chemokine Expression and Cell Trafficking During Immune ResponsesQ57227496
Deficient Positive Selection of CD4 T Cells in Mice Displaying Altered Repertoires of MHC Class II–Bound Self-PeptidesQ60641123
The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand BiosynthesisQ60719538
Blood and lymphatic endothelial cell-specific differentiation programs are stringently controlled by the tissue environmentQ61654360
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)42-53
P577publication date2007-11-25
P1433published inNature ImmunologyQ1071725
P1476titleThe sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
P478volume9

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cites work (P2860)
Q45980190A B cell-dependent mechanism restrains T cell transendothelial migration.
Q38704129A robust in vitro model for trans-lymphatic endothelial migration
Q30537889A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes
Q52900554Accumulation and local proliferation of antigen‐specific CD4+ T cells in antigen‐bearing tissue
Q35545433An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease
Q34805735Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis
Q42664459Arthritis: where are the T cells?
Q33977201Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management
Q30490219B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.
Q33489877Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model
Q30577349CD28 and ITK signals regulate autoreactive T cell trafficking.
Q92402334CD4 T cell sphingosine 1-phosphate receptor (S1PR)1 and S1PR4 and endothelial S1PR2 regulate afferent lymphatic migration
Q58063831CD69 modulates sphingosine-1-phosphate-induced migration of skin dendritic cells
Q33979875Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics
Q90854590Cellular traffic through afferent lymphatic vessels
Q35890970Chemoattractant receptors and lymphocyte egress from extralymphoid tissue: changing requirements during the course of inflammation.
Q37730789Chemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa
Q89899047Chikungunya virus evades antiviral CD8+ T cell responses to establish persistent infection in joint-associated tissues
Q39402889Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation
Q26781324Development and Function of Protective and Pathologic Memory CD4 T Cells
Q40627996Dietary B Vitamins and Serum C-Reactive Protein in Persons With Human Immunodeficiency Virus Infection: The Positive Living With HIV (POLH) Study
Q37711740Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration.
Q40092134Dynamics of influenza-induced lung-resident memory T cells underlie waning heterosubtypic immunity
Q50086043ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an Infectious Diseases perspective (Immune checkpoint inhibitors, cell adhesion inhibitors, sphingosine-1-phosphat
Q36063581Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation
Q37412329Epigenetic mechanisms of regulation of Foxp3 expression
Q37701937Evolving paradigms that determine the fate of an allograft
Q28081129Exit Strategies: S1P Signaling and T Cell Migration
Q47940254Exploiting lymphatic vessels for immunomodulation: Rationale, opportunities, and challenges.
Q33920116Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations
Q30503966FTY720 blocks egress of T cells in part by abrogation of their adhesion on the lymph node sinus
Q46246510FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow
Q64271793Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells
Q27026175Fingolimod for the treatment of neurological diseases-state of play and future perspectives
Q36108239From optical bench to cageside: intravital microscopy on the long road to rational vaccine design
Q42149313Functional specialization of islet dendritic cell subsets
Q37385266G protein-coupled receptors as potential drug targets for lymphangiogenesis and lymphatic vascular diseases
Q36124850Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic
Q28069933High Endothelial Venules and Lymphatic Vessels in Tertiary Lymphoid Organs: Characteristics, Functions, and Regulation
Q35587221Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease
Q37191908Human immunodeficiency virus type 1 gp120 reprogramming of CD4+ T-cell migration provides a mechanism for lymphadenopathy
Q40112735Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity
Q42511998IFN-γ promotes transendothelial migration of CD4+ T cells across the blood-brain barrier
Q40046462IL-7 plays a critical role for the homeostasis of allergen-specific memory CD4 T cells in the lung and airways
Q44221230Identification of FABP7 in fibroblastic reticular cells of mouse lymph nodes.
Q46505723Impaired initiation of contact hypersensitivity by FTY720.
Q33522245In situ patrolling of regulatory T cells is essential for protecting autoimmune exocrinopathy
Q54354196Inflammatory cytokines IL-6 and TNF-α regulate lymphocyte trafficking through the local lymph node.
Q28728804Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats
Q38173858Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.
Q90342813Insulin resistance disrupts cell integrity, mitochondrial function, and inflammatory signaling in lymphatic endothelium
Q37508056Integrin function in T-cell homing to lymphoid and nonlymphoid sites: getting there and staying there
Q36190599Interface between hemostasis and adaptive immunity
Q34340057Interleukin-1β expression is required for lysophosphatidic Acid-induced lymphangiogenesis in human umbilical vein endothelial cells
Q37246683Interstitial leukocyte migration and immune function
Q51832369Introduction: T Cell Trafficking in Inflammation and Immunity.
Q35032485LIGHT regulates inflamed draining lymph node hypertrophy.
Q64092961Leucocyte Trafficking via the Lymphatic Vasculature- Mechanisms and Consequences
Q36949921Local antigen in nonlymphoid tissue promotes resident memory CD8+ T cell formation during viral infection
Q36952932Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza
Q38151694Location, location, location: the impact of migratory heterogeneity on T cell function
Q35131321Low molecular weight hyaluronan induces lymphangiogenesis through LYVE-1-mediated signaling pathways
Q35733802Lymph node B lymphocyte trafficking is constrained by anatomy and highly dependent upon chemoattractant desensitization.
Q28742322Lymphangiogenesis is required for pancreatic islet inflammation and diabetes
Q92700267Lymphatic Migration of Immune Cells
Q38997287Lymphatic Regulation of Cellular Trafficking
Q90482453Lymphatic Vessel Network Structure and Physiology
Q26778332Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer
Q36405877Lymphatic reprogramming by Kaposi sarcoma herpes virus promotes the oncogenic activity of the virus-encoded G-protein-coupled receptor.
Q37602241Lymphatic vessels and tertiary lymphoid organs
Q37130397Lymphocyte homing and its role in the pathogenesis of IBD.
Q38095525Mechanistic perspective on the relationship between pyridoxal 5'-phosphate and inflammation
Q60046093MicroRNA-31 Reduces the Motility of Proinflammatory T Helper 1 Lymphocytes
Q26783009Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease
Q35691180Molecular mechanisms of CD8(+) T cell trafficking and localization
Q36284953Molecular regulation of lymphangiogenesis in development and tumor microenvironment
Q53129178N,N-dimethylsphingosine attenuates myocardial ischemia-reperfusion injury by recruiting regulatory T cells through PI3K/Akt pathway in mice.
Q33598397Naïve T cells re-distribute to the lungs of selectin ligand deficient mice
Q27329905Neutrophil recruitment limited by high-affinity bent β2 integrin binding ligand in cis.
Q33763039Novel trafficking routes for hematopoietic stem and progenitor cells
Q41649263Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction
Q35722619Outer Membrane Vesicle-Mediated Export of Processed PrtV Protease from Vibrio cholerae
Q33907800Persistence in Temporary Lung Niches: A Survival Strategy of Lung-Resident Memory CD8+ T Cells
Q30497438Podoplanin-expressing cells derived from bone marrow play a crucial role in postnatal lymphatic neovascularization
Q42146832Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels
Q41860308Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
Q33831778Quantitative lymphatic vessel trait analysis suggests Vcam1 as candidate modifier gene of inflammatory bowel disease.
Q93015477Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis
Q35551835Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors
Q36924404Regulation of the roles of sphingosine 1-phosphate and its type 1 G protein-coupled receptor in T cell immunity and autoimmunity
Q34966662Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.
Q52760412Regulatory T cells with superior immunosuppressive capacity emigrate from the inflamed colon to draining lymph nodes.
Q91782570S1P-S1PR1 Signaling: the "Sphinx" in Osteoimmunology
Q30498266Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II
Q36356934Shaping the landscape: metabolic regulation of S1P gradients
Q91801206Sphingosine-1-Phosphate Facilitates Skin Wound Healing by Increasing Angiogenesis and Inflammatory Cell Recruitment with Less Scar Formation
Q47137537Sphingosine-1-Phosphate Promotes the Persistence of Activated CD4 T Cells in Inflamed Sites.
Q26766425Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential
Q58498450Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function
Q34474363Sphingosine-1-phosphate and immune regulation: trafficking and beyond
Q36240870Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function
Q28235893Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection
Q39618723Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
Q38166250Sphingosine-1-phosphate: a master regulator of lymphocyte egress and immunity
Q33845720Systemic hematogenous maintenance of memory inflation by MCMV infection.
Q37521315T Cell Trafficking through Lymphatic Vessels.
Q36646448T cell-intrinsic S1PR1 regulates endogenous effector T-cell egress dynamics from lymph nodes during infection.
Q51890214T cells as pioneers: antigen-specific T cells condition inflamed sites for high-rate antigen-non-specific effector cell recruitment.
Q38798843T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function.
Q55640649Tanshinone IIA promotes the differentiation of bone marrow mesenchymal stem cells into neuronal-like cells in a spinal cord injury model.
Q47725521Targeting S1P in Inflammatory bowel disease: new avenues for modulating intestinal leukocyte migration
Q42272995Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival
Q64093075Th2-T Maintain Life-Long Allergic Memory in Experimental Asthma in Mice
Q42913146The Origin and Maturity of Dendritic Cells Determine the Pattern of Sphingosine 1-Phosphate Receptors Expressed and Required for Efficient Migration
Q37010807The alliance of sphingosine-1-phosphate and its receptors in immunity
Q53451931The cooperative role of S1P3 with LYVE-1 in LMW-HA-induced lymphangiogenesis.
Q53622050The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes.
Q37293864The influence of sphingosine-1-phosphate receptor signaling on lymphocyte trafficking: how a bioactive lipid mediator grew up from an "immature" vascular maturation factor to a "mature" mediator of lymphocyte behavior and function.
Q38100061The integration of T cell migration, differentiation and function
Q34744147The interaction between LYVE-1 with hyaluronan on the cell surface may play a role in the diversity of adhesion to cancer cells
Q34015299The lymphatic system in health and disease
Q37449565The molecular signature of tissue resident memory CD8 T cells isolated from the brain
Q37319760The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.
Q35035148Therapeutic use of a selective S1P1 receptor modulator ponesimod in autoimmune diabetes
Q33817100Thymic emigration: when and how T cells leave home
Q26829804Tissue-resident memory T cells
Q37352068Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells
Q27341886Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
Q64076907Triggering the Resolution of Immune Mediated Inflammatory Diseases: Can Targeting Leukocyte Migration Be the Answer?
Q42369832Unique Features of Pancreatic-Resident Regulatory T Cells in Autoimmune Type 1 Diabetes
Q37293908Vascular biology: the role of sphingosine 1-phosphate in both the resting state and inflammation
Q42650601Vascular endothelial growth factor c/vascular endothelial growth factor receptor 3 signaling regulates chemokine gradients and lymphocyte migration from tissues to lymphatics
Q37318829Visualizing dendritic cell migration within the skin
Q52909911[Tissue retention of T cells as a therapeutic target in rheumatoid arthritis].