Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons

scientific article published on February 1999

Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1046/J.1471-4159.1999.0720716.X
P698PubMed publication ID9930745
P5875ResearchGate publication ID227934770

P2093author name stringD K Kim
Y H Kim
J Y Koh
J H Seo
J Y Hwang
P2860cites workRiluzole specifically blocks inactivated Na channels in myelinated nerve fibreQ43795777
21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell culturesQ44082608
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosisQ45291121
Riluzole anesthesia: use-dependent block of presynaptic glutamate fibersQ46162561
Trolox attenuates cortical neuronal injury induced by iron, ultraviolet light, glucose deprivation, or AMPA.Q48158059
Neuroprotective effects of glutamate antagonists and extracellular acidityQ48268510
Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivoQ48396095
Inhibition of synaptosomal veratridine-induced sodium influx by antidepressants and neuroleptics used in chronic painQ48830167
NMDA excitotoxicity and free radical generation in rat brain homogenates: application of a chemiluminescence assayQ48853050
Analysis of the functional effects of a mutation in SOD1 associated with familial amyotrophic lateral sclerosisQ57419138
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentationQ24642901
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosisQ28131805
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutationQ29547561
Assay for lipid peroxides in animal tissues by thiobarbituric acid reactionQ29616762
Mutations in copper-zinc superoxide dismutase that cause amyotrophic lateral sclerosis alter the zinc binding site and the redox behavior of the proteinQ30425734
Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytesQ34306269
Altered Na(+)-channel function as an in vitro model of the ischemic penumbra: action of lubeluzole and other neuroprotective drugsQ34416753
Glutamate neurotoxicity and diseases of the nervous systemQ34560997
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosisQ34736976
Neuroprotective effects of riluzole on N-methyl-D-aspartate- or veratridine-induced neurotoxicity in rat hippocampal slicesQ36712664
A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxideQ37550536
The arachidonic acid cascade, eicosanoids, and signal transduction.Q40642491
Arachidonic acid as a neurotoxic and neurotrophic substanceQ40937091
Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acidsQ41083216
Volume-sensitive chloride channels blocked by neuroprotective drugs in human glial cells (U-138MG).Q41170148
Staurosporine-induced neuronal apoptosis.Q41672506
Purification of a 100 kDa phospholipase A2 from spleen, lung and kidney: antiserum raised to pig spleen phospholipase A2 recognizes a similar form in bovine lung, kidney and platelets, and immunoprecipitates phospholipase A2 activityQ42030487
Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of actionQ42154486
Effect of oxidative stress on excitatory amino acid release by cerebral cortical synaptosomesQ42491109
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)716-723
P577publication date1999-02-01
P1433published inJournal of NeurochemistryQ6295643
P1476titleAntioxidative and proapoptotic effects of riluzole on cultured cortical neurons
P478volume72

Reverse relations

cites work (P2860)
Q39356957Effect of glutamate and riluzole on manganese-induced apoptotic cell signaling in neuronally differentiated mouse P19 Cells
Q40238809Effect of riluzole on Ca2+ movement and cytotoxicity in Madin-Darby canine kidney cells
Q40881474In vitro antioxidant neuroprotective activity of BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation
Q39279068Intracerebroventricular administration of riluzole prevents morphine-induced apoptosis in the lumbar region of the rat spinal cord.
Q37711265Low molecular weight phospholipases A2 in mammalian brain and neural cells: roles in functions and dysfunctions
Q36513407Models of multiple system atrophy
Q43782689Neuroprotective effect of riluzole in MPTP-treated mice
Q26801239Oxidative Stress in Neurodegenerative Diseases
Q92227676Riluzole Selective Antioxidant Effects in Cell Models Expressing Amyotrophic Lateral Sclerosis Endophenotypes
Q40307571Specific regulation of rat glial cell line-derived neurotrophic factor gene expression by riluzole in C6 glioma cells
Q92277261The Effects of Riluzole on Cisplatin-induced Ototoxicity
Q34974850Therapeutic developments in the treatment of amyotrophic lateral sclerosis

Search more.