Thrombin stimulates insulin secretion via protease-activated receptor-3

scientific article published on 8 January 2016

Thrombin stimulates insulin secretion via protease-activated receptor-3 is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/19382014.2015.1118195
P932PMC publication ID4878264
P698PubMed publication ID26742564

P50authorAnnika S AxelssonQ88313482
Claes B WollheimQ88313489
Anders H RosengrenQ88313495
Yunzhao TangQ89347267
Sonja HänzelmannQ114418422
Robert CasteloQ42551515
Enming ZhangQ43266380
Emre GuneyQ48975661
Albert SalehiQ55324938
P2093author name stringJinling Wang
Ivan G Costa
Eva Zetterberg
Erik Berntorp
Hannah Nenonen
P2860cites workStimulatory effect of bradykinin on insulin release from the perfused rat pancreasQ72268036
How obesity causes diabetes in Zucker diabetic fatty ratsQ81066858
Metabolic syndrome, haemostasis and thrombosisQ81389911
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Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitusQ44205749
A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1.Q44297979
Tethered ligand-derived peptides of proteinase-activated receptor 3 (PAR3) activate PAR1 and PAR2 in Jurkat T cellsQ44899120
Effects of hyperglycemia and hyperinsulinemia on circulating tissue factor procoagulant activity and platelet CD40 ligandQ46870198
Zucker Diabetic Fatty rats exhibit hypercoagulability and accelerated thrombus formation in the Arterio-Venous shunt model of thrombosis.Q51141879
Protease-activated receptor 3 is a second thrombin receptor in humansQ24310957
Pathway level analysis of gene expression using singular value decompositionQ24814174
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.Q27863762
Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized ratsQ28363779
Hierarchical organization of modularity in metabolic networksQ29618451
Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handlingQ30430981
IUPHAR-DB: updated database content and new featuresQ30485756
Reverse engineering molecular regulatory networks from microarray data with qp-graphs.Q33403836
Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetesQ34310863
An atlas and functional analysis of G-protein coupled receptors in human islets of LangerhansQ34345899
Exploiting protein-protein interaction networks for genome-wide disease-gene prioritizationQ34426791
Quantitative study of insulin secretion and clearance in normal and obese subjectsQ35809498
Five stages of evolving beta-cell dysfunction during progression to diabetesQ35961960
Minimal model: perspective from 2005.Q36378808
Effects of hyperglycemia and hyperinsulinemia on the tissue factor pathway of blood coagulationQ36839933
Novel mechanisms for activated protein C cytoprotective activities involving noncanonical activation of protease-activated receptor 3.Q37065714
Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusQ37141727
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetesQ37443837
Mitochondrial signals drive insulin secretion in the pancreatic β-cellQ37904355
Diabetes mellitus and the β cell: the last ten yearsQ37994282
Proteinase-activated receptors (PARs) and calcium signaling in cancerQ37997713
Incretin-based therapies for type 2 diabetes mellitus: a review of direct comparisons of efficacy, safety and patient satisfactionQ38069507
High glucose levels enhance platelet activation: involvement of multiple mechanismsQ38313872
Oscillations of phospholipase C activity triggered by depolarization and Ca2+ influx in insulin-secreting cellsQ40573518
A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance: evidence for a pathogenic role of relative hyperinsulinemia.Q40734688
Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pitsQ40868681
Mechanisms of bradykinin-induced insulin secretion in clonal beta cell line RINm5F.Q41088439
Activation of protease-activated receptors 3 and 4 accelerates tissue factor-induced thrombin generation on the surface of vascular smooth muscle cellsQ42320997
Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathwayQ42470903
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P433issue4
P304page(s)e1118195
P577publication date2015-01-01
P1433published inIsletsQ26853851
P1476titleThrombin stimulates insulin secretion via protease-activated receptor-3
P478volume7

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