Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma

scientific article published on 24 July 2013

Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BM400619V
P932PMC publication ID3758899
P698PubMed publication ID23841817

P2093author name stringErin B Lavik
Andrew J Shoffstall
Jeffrey S Ustin
Lydia M Everhart
Matthew E Varley
Adam M Shick
Eric S Soehnlen
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Controlling Ligand Surface Density Optimizes Nanoparticle Binding to ICAM-1Q39648047
Fibrin sealant foam sprayed directly on liver injuries decreases blood loss in resuscitated ratsQ40750768
Intravenous hemostatic nanoparticles increase survival following blunt trauma injuryQ41215308
Intravenous hemostat: nanotechnology to halt bleeding.Q41470605
Functionalized poly(lactic-co-glycolic acid) enhances drug delivery and provides chemical moieties for surface engineering while preserving biocompatibilityQ41826178
Influence of Targeting Ligand Flexibility on Receptor Binding of Particulate Drug Delivery SystemsQ42833947
A simple synthetic route to the formation of a block copolymer of poly(lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applicationsQ43586658
Acute toxicity of intravenously administered microfabricated silicon dioxide drug delivery particles in mice: preliminary findingsQ43765615
Liver injury as a model of uncontrolled hemorrhagic shock: resuscitation with different hypertonic regimensQ46309466
Preparation of poly(ethylene glycol) protected nanoparticles with variable bioconjugate ligand densityQ46401536
Resuscitation of uncontrolled liver hemorrhage: effects on bleeding, oxygen delivery, and oxygen consumptionQ46833271
Size and shape effects in the biodistribution of intravascularly injected particles.Q47588670
Immobilized Arg-Gly-Asp (RGD) peptides of varying lengths as structural probes of the platelet glycoprotein IIb/IIIa receptorQ50132660
Mimicking adhesive functionalities of blood platelets using ligand-decorated liposomes.Q51759013
Injury Severity and Causes of Death From Operation Iraqi Freedom and Operation Enduring Freedom: 2003???2004 Versus 2006Q56807533
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Trauma and pulmonary thromboembolism: an experimental study on their correlationQ80670603
Peptide-decorated liposomes promote arrest and aggregation of activated platelets under flow on vascular injury relevant protein surfaces in vitroQ83790128
Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhageQ83937026
Heteromultivalent liposomal nanoconstructs for enhanced targeting and shear-stable binding to active platelets for site-selective vascular drug deliveryQ84927729
In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstructQ85982195
P433issue8
P921main subjectnanoparticleQ61231
P304page(s)2790-2797
P577publication date2013-07-24
P1433published inBiomacromoleculesQ1768006
P1476titleTuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma
P478volume14

Reverse relations

cites work (P2860)
Q37531135Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and -spheres in mice
Q60998516Engineering Intravenously Administered Nanoparticles to Reduce Infusion Reaction and Stop Bleeding in a Large Animal Model of Trauma
Q37278074Hemostatic Nanoparticles Improve Survival Following Blunt Trauma Even after 1 Week Incubation at 50 °C.
Q57376754Hemostatic polymers: the concept, state of the art and perspectives
Q38168784Hemostatic strategies for traumatic and surgical bleeding
Q30584438Intravenously administered nanoparticles increase survival following blast trauma
Q41915826Materials design at the interface of nanoparticles and innate immunity.
Q50915888Peptide valency plays an important role in the activity of a synthetic fibrin-crosslinking polymer.
Q38813909Surgical adjuncts to noncompressible torso hemorrhage as tools for patient blood management
Q35858739Synthetic Strategies for Engineering Intravenous Hemostats
Q48267294Thrombin@Fe3O4 nanoparticles for use as a hemostatic agent in internal bleeding.
Q27026630Vascular targeting of nanocarriers: perplexing aspects of the seemingly straightforward paradigm

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