Studies of activated GPIIb/IIIa receptors on the luminal surface of adherent platelets. Paradoxical loss of luminal receptors when platelets adhere to high density fibrinogen

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Studies of activated GPIIb/IIIa receptors on the luminal surface of adherent platelets. Paradoxical loss of luminal receptors when platelets adhere to high density fibrinogen is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI116899
P932PMC publication ID288480
P698PubMed publication ID8254034

P2093author name stringB S Coller
L E Scudder
D K Galanakis
J L Kutok
S M West
G S Rudomen
K T Springer
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Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix.Q52485526
Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report--Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis.Q53424158
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Interaction of thrombin-stimulated platelets with vitronectin (S-protein of complement) substrate: inhibition by a monoclonal antibody to glycoprotein IIb-IIIa complexQ68054237
Modulation of platelet function through adhesion receptors. A dual role for glycoprotein IIb-IIIa (integrin alpha IIb beta 3) mediated by fibrinogen and glycoprotein Ib-von Willebrand factorQ68142029
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An integrin receptor on normal and thrombasthenic platelets that binds thrombospondinQ69108026
Increased surface expression of the membrane glycoprotein IIb/IIIa complex induced by platelet activation. Relationship to the binding of fibrinogen and platelet aggregationQ69117879
The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complexQ69822042
Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human plateletsQ69871824
Thrombin-induced platelet aggregates have a dynamic structure. Time-dependent redistribution of glycoprotein IIb-IIIa complexes and secreted adhesive proteinsQ70150082
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2796-2806
P577publication date1993-12-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleStudies of activated GPIIb/IIIa receptors on the luminal surface of adherent platelets. Paradoxical loss of luminal receptors when platelets adhere to high density fibrinogen
P478volume92

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cites work (P2860)
Q77336159Activation of the GP IIb-IIIa complex induced by platelet adhesion to collagen is mediated by both alpha2beta1 integrin and GP VI
Q35266443Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells
Q41125713Immunocytochemical aspects of platelet membrane glycoproteins and adhesive proteins during activation.
Q30479586Ligand density dramatically affects integrin alpha IIb beta 3-mediated platelet signaling and spreading
Q40943762PAR1 activation initiates integrin engagement and outside-in signalling in megakaryoblastic CHRF-288 cells
Q48017537Peptide LSARLAF activates alpha(IIb)beta3 on resting platelets and causes resting platelet aggregate formation without platelet shape change
Q39781545Platelet GPIIb/IIIa antagonists: the first anti-integrin receptor therapeutics
Q56945638Randomised trial of coronary intervention with antibody against platelet IIb/IIIa iritegrin for reduction of clinical restenosis: results at six months
Q74587116Reactivity of human platelets with immobilized fibrinogen is dictated by the chemical character of the surface
Q27301036Swing-out of the β3 hybrid domain is required for αIIbβ3 priming and normal cytoskeletal reorganization, but not adhesion to immobilized fibrinogen
Q35858739Synthetic Strategies for Engineering Intravenous Hemostats
Q42579276Tuning ligand density on intravenous hemostatic nanoparticles dramatically increases survival following blunt trauma

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