A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa

scientific article

A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI110973
P932PMC publication ID1129188
P698PubMed publication ID6308050

P2093author name stringE I Peerschke
C A Sullivan
B S Coller
L E Scudder
P2860cites workgamma and alpha chains of human fibrinogen possess sites reactive with human platelet receptorsQ24301146
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Continuous cultures of fused cells secreting antibody of predefined specificityQ26776979
A Film Detection Method for Tritium-Labelled Proteins and Nucleic Acids in Polyacrylamide GelsQ29547782
Molecular differences of exposed surface proteins on thrombasthenic platelet plasma membranesQ33339989
Defective ristocetin-induced platelet aggregation in von Willebrand's disease and its correction by factor VIIIQ33462122
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasisQ33463842
An Abnormal Platelet Glycoprotein Pattern in Three Cases of Glanzmann's ThrombastheniaQ33463846
Thromboxane Synthesis and the Platelet Release Reaction in Bernard-Soulier Syndrome, Thrombasthenia Glanzmann and Hermansky-Pudlak SyndromeQ33471694
Exposure of platelet fibrinogen receptors by ADP and epinephrineQ33473239
Cycles of Agglutination-Disagglutination Induced by Ristocetin in Thrombasthenic PlateletsQ33473264
Relationship between fibrinogen binding and the platelet glycoprotein deficiencies in Glanzmann's thrombasthenia type I and type II.Q33478516
Antibodies against platelet membrane glycoproteins. II. Influence on ADP- and collagen-induced platelet aggregation, crossed immunoelectrophoresis studies and relevance to Glanzmann's thrombastheniaQ33478542
Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in in vivo cells from normal and leukemic patientsQ33483874
A molecular defect in thrombasthenic plateletsQ35194630
New Data on Glanzmann's ThrombastheniaQ36562989
A role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptorsQ37004238
Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogenQ37007168
Immunochemical evidence for protein abnormalities in platelets from patients with Glanzmann's thrombasthenia and Bernard-Soulier syndromeQ37021542
Isolation and quantitation of the platelet membrane glycoprotein deficient in thrombasthenia using a monoclonal hybridoma antibodyQ37026661
Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibodyQ37609861
The pH dependence of quantitative ristocetin-induced platelet aggregation: theoretical and practical implications-a new device for maintenance of platelet-rich plasma pHQ39088121
Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-SepharoseQ39218339
Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein AQ39513417
???Q64800736
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigensQ39548957
A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell linesQ39683818
Plasmin inhibition of thrombin-induced platelet aggregationQ39735110
Normal pregnancy in a patient with a prior postpartum factor VIII inhibitor: with observations on pathogenesis and prognosisQ40261271
Interrelations of Platelet Aggregation and SecretionQ40691389
Ionophore a 23187 and thrombasthenic platelets : a model for dissociating serotonin release and thromboxane formation from true aggregationQ41139007
Human platelets possess an inducible and saturable receptor specific for fibrinogenQ41629256
Studies on the factor VIII/von Willebrand factor antigen on human plateletsQ45878348
The effect of stir bar size and shape on quantitative platelet aggregationQ47342077
Studies of platelet function and proteins in 3 patients with Glanzmann's thrombastheniaQ47818855
Statistical analysis of repetitive subcloning by the limiting dilution technique with a view toward ensuring hybridoma monoclonality.Q52433899
Inhibition of von Willebrand factor-dependent platelet function by increased platelet cyclic AMP and its prevention by cytoskeleton-disrupting agentsQ52499595
Numbers of Receptor Sites from Scatchard Graphs: Facts and FantasiesQ52715482
Effects of Adenosine Diphosphate and Adrenaline on Mean Platelet ShapeQ52760646
Comparison of fibrinogen association with normal and thrombasthenic platelets on exposure to ADP or chymotrypsinQ66955875
The effects of citrate and extracellular calcium ions on the platelet release reaction induced by adenosine diphosphate and collagenQ66968585
Human Normal and Leukemia Cell Surface Antigens. Mouse Monoclonal Antibodies as ProbesQ67016230
Acquired IgG antibody occurring in a thrombasthenic patient: its effect on human platelet functionQ67325000
Effects of ADP and ATP on Bovine Fibrinogen- and Ristocetin-Induced Platelet Aggregation in Glanzmann's ThrombastheniaQ67348850
Asialofibrinogen supports platelet aggregation and adhesion to glassQ67466902
Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresisQ67556563
Clot retraction: evaluation in dilute suspensions of platelet-rich plasma and gel-separated plateletsQ67740203
The Effect of Platelet Membrane Antibodies on Aggregation and ReleaseQ68935471
Platelet Shape Change and AggregationQ69379124
Isolation, purification, and partial characterization of platelet membrane glycoproteins IIb and IIIaQ70539259
The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresisQ70549345
Glycoproteins of platelet membranes from Glanzmann's thrombasthenia. A comparison with normal using carbohydrate-specific or protein-specific labelling techniques and high-resolution two-dimensional gel electrophoresisQ70664632
Platelet membrane studies in the May-Hegglin anomalyQ70820919
Platelet Adhesion Induced by Fibrinogen Adsorbed onto GlassQ71115194
Ristocetin--a new tool in the investigation of platelet aggregationQ71153335
Interaction of normal, thrombasthenic, and Bernard-Soulier platelets with immobilized fibrinogen: defective platelet-fibrinogen interaction in thrombastheniaQ71493148
Correlation between fibrinogen binding to human platelets and platelet aggregabilityQ71496685
Crossed immunoelectrophoresis of human platelet membranes. The major antigen consists of a complex of glycoproteins, GPIIb and GPIIIa, held together by Ca2+ and missing in Glanzmann's thrombastheniaQ71606383
Fibrinogen and platelets in the primary arrest of bleeding. Studies in two patients with congenital afibrinogenemiaQ71787277
Influence of fibrinogen on the aggregation of washed human blood platelets induced by adenosine diphosphate, thrombin, collagen, and adrenalineQ72645911
Platelet function in congenital afibrinogenemiaQ72654398
Involvement of divalent cations in the complex between the platelet glycoproteins IIb and IIIaQ72656125
Exposure of platelet fibrinogen-binding sites by collagen, arachidonic acid, and ADP: inhibition by a monoclonal antibody to the glycoprotein IIb-IIIa complexQ72771425
Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodiesQ72779664
Platelet function in a patient with thrombastheniaQ72811872
Aggregation, adhesion, and viscous metamorphosis of platelets in congenital fibrinogen deficienciesQ72868848
Effects of chymotrypsin and adenosine diphosphate on the exposure of fibrinogen receptors on normal human and Glanzmann's thrombasthenic plateletsQ72895038
EFFECT OF FIBRINOGEN ON THE AGGREGATION OF PLATELETS BY ADENOSINE DIPHOSPHATEQ77201766
PLASMA THROMBOCYTE-AGGLUTINATING ACTIVITY AND FIBRINOGEN. SYNERGISM WITH ADENOSINE DIPHOSPHATEQ78308703
The preparation of human fibrinogen free of plasminogenQ79027094
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
monoclonal antibodyQ422248
P304page(s)325-338
P577publication date1983-07-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleA murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa
P478volume72

Reverse relations

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