Polyomavirus small T antigen controls viral chromatin modifications through effects on kinetics of virus growth and cell cycle progression

scientific article published on 11 July 2007

Polyomavirus small T antigen controls viral chromatin modifications through effects on kinetics of virus growth and cell cycle progression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00821-07
P932PMC publication ID2045420
P698PubMed publication ID17626093
P5875ResearchGate publication ID6212269

P2093author name stringThomas L Benjamin
Michael George
H Isaac Chen
Jean Dahl
P2860cites workMitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodesQ24290197
Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signallingQ24532278
Host range and cell cycle activation properties of polyomavirus large T-antigen mutants defective in pRB bindingQ36637042
Truncated forms of the polyomavirus middle T antigen can substitute for the small T antigen in lytic infectionQ36856756
Virion assembly defect of polyomavirus hr-t mutants: underphosphorylation of major capsid protein VP1 before viral DNA encapsidationQ36900930
A polyoma mutant that encodes small T antigen but not middle T antigen demonstrates uncoupling of cell surface and cytoskeletal changes associated with cell transformationQ36955526
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.Q37605239
Host range transforming gene of polyoma virus plays a role in virus assemblyQ37614739
Biochemical characterization of phosphorylation site mutants of simian virus 40 large T antigen: evidence for interaction between amino- and carboxy-terminal domainsQ38336379
Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A.Q39576996
Binding of polyomavirus small T antigen to protein phosphatase 2A is required for elimination of p27 and support of S-phase induction in concert with large T antigenQ39596484
Simian Virus 40 Large T Antigen Is Phosphorylated at Multiple Sites Clustered in Two Separate RegionsQ40142486
DNA sequence alterations in Hr-t deletion mutants of polyoma virusQ40237140
Dynamic changes in histone H3 lysine 9 methylations: identification of a mitosis-specific function for dynamic methylation in chromosome congression and segregationQ40337035
PP2A-dependent transactivation of the cyclin A promoter by SV40 ST is mediated by a cell cycle-regulated E2F site.Q40464019
Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.Q40789316
Induction and utilization of an ATM signaling pathway by polyomavirusQ42109796
Polyomavirus hr-t mutant-specific induction of a G2/M cell-cycle arrest that is not overcome by the expression of middle T and/or small T.Q42803618
Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A.Q42824374
Association of Polyomavirus middle tumor antigen with phospholipase C-gamma 1.Q42827436
Histone deacetylation is required for progression through mitosis in tobacco cellsQ45230151
Identification of DNA sequence changes leading to loss of transforming ability in polyoma virusQ45804021
Separation of histone variants and post-translationally modified isoforms by triton/acetic acid/urea polyacrylamide gel electrophoresisQ46761029
Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNAQ72855537
Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinasesQ24537111
Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigenQ24603984
Induction of cyclin D1 by simian virus 40 small tumor antigenQ24648223
The language of covalent histone modificationsQ27860931
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulationQ28141828
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tailsQ28216534
Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2AQ28254771
Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoterQ28346664
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domainQ28609769
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assemblyQ29614718
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensationQ29617905
Host range mutants of polyoma virusQ33703831
Transactivation of murine cyclin A by polyomavirus large and small T antigens.Q33843350
Role of middle T-small T in the lytic cycle of polyomavirus: control of the early-to-late transcriptional switch and viral DNA replicationQ33853931
Histone H4 acetylation of euchromatin and heterochromatin is cell cycle dependent and correlated with replication rather than with transcriptionQ33926085
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.Q34181194
Histone H3 phosphorylation and cell divisionQ34290245
Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activationQ34308397
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.Q34345750
Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeastQ34443938
Cell transformation by the middle T-antigen of polyoma virusQ34468798
Protein phosphatase 2A antagonizes ATM and ATR in a Cdk2- and Cdc7-independent DNA damage checkpointQ34519707
Deficiency in histone acetylation in nontransforming host range mutants of polyoma virusQ34996018
Independent contributions of polyomavirus middle T and small T to the regulation of early and late gene expression and DNA replicationQ35023729
An epigenetic road map for histone lysine methylationQ35120983
Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth controlQ35539933
Protein phosphatase 2A activity affects histone H3 phosphorylation and transcription in Drosophila melanogasterQ35661433
Histone hyperacetylation in the coding region of chromatin undergoing transcription in SV40 minichromosomes is a dynamic process regulated directly by the presence of RNA polymerase II.Q35741523
Enhancer-mediated role for polyomavirus middle T/small T in DNA replication.Q35829772
Phosphorylation sites in polyomavirus large T antigen that regulate its function in viral, but not cellular, DNA synthesisQ35891127
Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigenQ36253069
Tumor induction by a transformation-defective polyoma virus mutant blocked in signaling through ShcQ36298429
Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformationQ36298676
The relationship between histone H3 phosphorylation and acetylation throughout the mammalian cell cycle.Q36579410
P4510describes a project that usesImageJQ1659584
P433issue18
P407language of work or nameEnglishQ1860
P304page(s)10064-10071
P577publication date2007-07-11
P1433published inJournal of VirologyQ1251128
P1476titlePolyomavirus small T antigen controls viral chromatin modifications through effects on kinetics of virus growth and cell cycle progression
P478volume81

Reverse relations

cites work (P2860)
Q38751556Activation of DNA damage repair pathways by murine polyomavirus
Q38632111Comparisons between Murine Polyomavirus and Simian Virus 40 Show Significant Differences in Small T Antigen Function
Q37834897Epigenetic modulation of host: new insights into immune evasion by viruses
Q39009104Global profiling of histone modifications in the polyomavirus BK virion minichromosome
Q39473946In vitro reconstitution of SV40 particles that are composed of VP1/2/3 capsid proteins and nucleosomal DNA and direct efficient gene transfer
Q90592503Murine polyomavirus DNA transitions through spatially distinct nuclear replication subdomains during infection
Q35774163Viral epigenetics

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