| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Ting Zhou | |
| Jiming Kong | |||
| Michael Namaka | |||
| Jessica Truong | |||
| Tina Khorshid Ahmad | |||
| Kiana Gozda | |||
| P2860 | cites work | Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) | Q24201081 |
| Oxidant treatment causes a dose-dependent phenotype of apoptosis in cultured motoneurons | Q77696049 | ||
| Motor neurone disease | Q78306103 | ||
| Astroglial alterations in amyotrophic lateral sclerosis (ALS) model of slow glutamate excitotoxicity in vitro | Q79236027 | ||
| Hypothesis: gut as source of motor neuron toxin in the development of ALS | Q81374531 | ||
| Linking hypoxic and oxidative insults to cell death mechanisms in models of ALS | Q82632554 | ||
| Multiple sclerosis and amyotrophic lateral sclerosis: is there a link? | Q82832644 | ||
| A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement | Q24299243 | ||
| Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia | Q24600027 | ||
| Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis | Q24619298 | ||
| Exome sequencing reveals VCP mutations as a cause of familial ALS | Q24631513 | ||
| A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD | Q24634583 | ||
| Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology | Q26744749 | ||
| Amyotrophic lateral sclerosis and environmental factors | Q26749342 | ||
| Recent advances in amyotrophic lateral sclerosis | Q26749521 | ||
| A comprehensive review of amyotrophic lateral sclerosis | Q26775401 | ||
| Amyotrophic Lateral Sclerosis: New Perpectives and Update | Q26781051 | ||
| Brain-Specific Cytoskeletal Damage Markers in Cerebrospinal Fluid: Is There a Common Pattern between Amyotrophic Lateral Sclerosis and Primary Progressive Multiple Sclerosis? | Q26799233 | ||
| The role of glutamine synthetase and glutamate dehydrogenase in cerebral ammonia homeostasis | Q26851324 | ||
| State of play in amyotrophic lateral sclerosis genetics | Q26864816 | ||
| Oxidative stress and mitochondrial damage: importance in non-SOD1 ALS | Q27023941 | ||
| Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS | Q28078651 | ||
| Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Q28131672 | ||
| Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
| Early and selective loss of neuromuscular synapse subtypes with low sprouting competence in motoneuron diseases | Q28139487 | ||
| Multiple sclerosis | Q28214785 | ||
| Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis | Q28236796 | ||
| Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis | Q28237200 | ||
| A perspective on the role of class III semaphorin signaling in central nervous system trauma | Q28251368 | ||
| Endocannabinoids in Multiple Sclerosis and Amyotrophic Lateral Sclerosis | Q28267822 | ||
| Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases | Q28269333 | ||
| NEK1 variants confer susceptibility to amyotrophic lateral sclerosis | Q28277378 | ||
| Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons | Q28298056 | ||
| The role of microbiome in central nervous system disorders | Q28304749 | ||
| Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis | Q28482111 | ||
| Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q28585525 | ||
| A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis | Q28728672 | ||
| Acute exercise increases brain region-specific expression of MCT1, MCT2, MCT4, GLUT1, and COX IV proteins. | Q54370103 | ||
| Inhibition of CNS remyelination by the presence of semaphorin 3A. | Q54383932 | ||
| SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis | Q55671566 | ||
| Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits | Q57187240 | ||
| Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish | Q57244941 | ||
| Axonal Loss and Neurofilament Phosphorylation Changes Accompany Lesion Development and Clinical Progression in Multiple Sclerosis | Q57562094 | ||
| MS and autoimmune disorders | Q57912288 | ||
| Epidemiology of Amyotrophic Lateral Sclerosis and Effect of Riluzole on Disease Course | Q58050262 | ||
| Amyotrophic lateral sclerosis | Q59219368 | ||
| Apoptosis-inducing factor and cyclophilin A cotranslocate to the motor neuronal nuclei in amyotrophic lateral sclerosis model mice. | Q64957450 | ||
| Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus | Q71358977 | ||
| White matter injury in amyotrophic lateral sclerosis (ALS) | Q71498208 | ||
| The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids | Q73263349 | ||
| Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man | Q75310510 | ||
| Leaky intestine and impaired microbiome in an amyotrophic lateral sclerosis mouse model | Q35588631 | ||
| Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways | Q35624305 | ||
| Roles of mitochondria in health and disease. | Q35641708 | ||
| White matter injury mechanisms | Q35699486 | ||
| Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination | Q35753667 | ||
| Potential role of gut microbiota and tissue barriers in Parkinson's disease and amyotrophic lateral sclerosis | Q35779264 | ||
| The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration | Q35836498 | ||
| Roles of white matter in central nervous system pathophysiologies | Q35846494 | ||
| CSF neurofilament light chain reflects corticospinal tract degeneration in ALS. | Q35935100 | ||
| Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1 | Q36112113 | ||
| Monocarboxylate transporters in the central nervous system: distribution, regulation and function. | Q36161586 | ||
| The Emerging Role of the Gut Microbiome in Adult Patients With Multiple Sclerosis | Q36185511 | ||
| Apoptosis in amyotrophic lateral sclerosis--what is the evidence? | Q36201880 | ||
| Amyotrophic lateral sclerosis and the clinical potential of dexpramipexole | Q36202825 | ||
| Golgi fragmentation in amyotrophic lateral sclerosis, an overview of possible triggers and consequences. | Q36211097 | ||
| FoxG1 promotes the survival of postmitotic neurons | Q36267774 | ||
| Tract-specific white matter correlates of fatigue and cognitive impairment in benign multiple sclerosis | Q36295194 | ||
| Male-specific differences in proliferation, neurogenesis, and sensitivity to oxidative stress in neural progenitor cells derived from a rat model of ALS | Q36384621 | ||
| BDNF in sensory neurons and chronic pain | Q36413814 | ||
| Therapeutic Advances and Future Prospects in Progressive Forms of Multiple Sclerosis | Q36484443 | ||
| Neurotrophic factors--a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases? | Q36952207 | ||
| Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls | Q37040077 | ||
| The Brain-Gut-Microbiome Axis: What Role Does It Play in Autism Spectrum Disorder? | Q37065375 | ||
| Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS. | Q37087752 | ||
| Motor Cortex Excitability and BDNF Levels in Chronic Musculoskeletal Pain According to Structural Pathology | Q37096934 | ||
| Structural and Functional Brain Correlates of Cognitive Impairment in Euthymic Patients with Bipolar Disorder. | Q37119297 | ||
| Axon-glial signaling and the glial support of axon function | Q37193060 | ||
| The role of dorsal root ganglia activation and brain-derived neurotrophic factor in multiple sclerosis. | Q37294255 | ||
| Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism | Q37369313 | ||
| Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model. | Q37406411 | ||
| Emerging Concepts on the Gut Microbiome and Multiple Sclerosis. | Q37428539 | ||
| The role of CNS glia in preserving axon function | Q37600162 | ||
| Riluzole, neuroprotection and amyotrophic lateral sclerosis. | Q37727244 | ||
| The "dying-back" phenomenon of motor neurons in ALS. | Q37807909 | ||
| White matter damage in Alzheimer disease and its relationship to gray matter atrophy | Q37823007 | ||
| Effects of gender in amyotrophic lateral sclerosis | Q37825010 | ||
| Multiple sclerosis as a neurodegenerative disease: pathology, mechanisms and therapeutic implications. | Q37860106 | ||
| VIP-induced neuroprotection of the developing brain | Q37869518 | ||
| Central nervous system myelin: structure, synthesis and assembly | Q37901690 | ||
| Sporadic amyotrophic lateral sclerosis: new hypothesis regarding its etiology and pathogenesis suggests that astrocytes might be the primary target hosting a still unknown external agent | Q37923822 | ||
| Stem cell challenges in the treatment of neurodegenerative disease. | Q37954422 | ||
| Cellular and molecular mechanisms of mitochondrial function | Q38061270 | ||
| The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol | Q38131625 | ||
| Oligodendroglia: metabolic supporters of axons | Q38132499 | ||
| The role of oligodendroglial dysfunction in amyotrophic lateral sclerosis | Q38237223 | ||
| ER stress and unfolded protein response in amyotrophic lateral sclerosis-a controversial role of protein disulphide isomerase | Q38292610 | ||
| Transcriptional Regulation of Brain-Derived Neurotrophic Factor (BDNF) by Methyl CpG Binding Protein 2 (MeCP2): a Novel Mechanism for Re-Myelination and/or Myelin Repair Involved in the Treatment of Multiple Sclerosis (MS). | Q38314584 | ||
| Flavonoid-based therapies in the early management of neurodegenerative diseases | Q38320199 | ||
| Endoplasmic reticulum stress and proteasomal system in amyotrophic lateral sclerosis | Q38527426 | ||
| Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and Disease | Q38560934 | ||
| Myelin plasticity in the central nervous system | Q38568475 | ||
| SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS. | Q38632098 | ||
| Excitotoxicity in ALS: Overstimulation, or overreaction? | Q38638552 | ||
| Amyotrophic Lateral Sclerosis (ALS) and Related Motor Neuron Diseases: An Overview | Q38657045 | ||
| Recent progress towards an effective treatment of amyotrophic lateral sclerosis using the SOD1 mouse model in a preclinical setting | Q38787800 | ||
| Protein Folding Alterations in Amyotrophic Lateral Sclerosis. | Q38804226 | ||
| ALS: Recent Developments from Genetics Studies | Q38817325 | ||
| Astrocytes in multiple sclerosis. | Q38840390 | ||
| Elevated caspase 3 activity and cytosolic cytochrome c in NT2 cybrids containing amyotrophic lateral sclerosis subject mtDNA. | Q38844121 | ||
| The role of semaphorin3A in myogenic regeneration and the formation of functional neuromuscular junctions on new fibres | Q38863834 | ||
| The role of the Wnt canonical signaling in neurodegenerative diseases | Q38883866 | ||
| The Axon Guidance Protein Semaphorin 3A Is Increased in the Motor Cortex of Patients With Amyotrophic Lateral Sclerosis | Q38902666 | ||
| Management and therapeutic perspectives in amyotrophic lateral sclerosis | Q38958585 | ||
| Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions | Q39009182 | ||
| Mutations of optineurin in amyotrophic lateral sclerosis | Q29614836 | ||
| ALS: a disease of motor neurons and their nonneuronal neighbors | Q29618000 | ||
| Remyelination in the CNS: from biology to therapy | Q30040587 | ||
| Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma | Q30308666 | ||
| Oligodendroglial alterations and the role of microglia in white matter injury: relevance to schizophrenia | Q30405077 | ||
| Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis | Q30883848 | ||
| White matter injury in ischemic stroke | Q31080285 | ||
| Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole | Q33529864 | ||
| White matter astrocytes in health and disease | Q33594651 | ||
| Axonal mitochondrial clusters containing mutant SOD1 in transgenic models of ALS. | Q33742751 | ||
| Non-invasive diffusion tensor imaging detects white matter degeneration in the spinal cord of a mouse model of amyotrophic lateral sclerosis. | Q33780459 | ||
| Mechanisms for neuronal degeneration in amyotrophic lateral sclerosis and in models of motor neuron death (Review). | Q33796727 | ||
| Semaphorin 3A signaling through neuropilin-1 is an early trigger for distal axonopathy in the SOD1G93A mouse model of amyotrophic lateral sclerosis | Q33811484 | ||
| Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice | Q33832905 | ||
| VIP neuroprotection against excitotoxic lesions of the developing mouse brain | Q33838449 | ||
| ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2. | Q33980322 | ||
| Oligodendroglia metabolically support axons and contribute to neurodegeneration. | Q34032818 | ||
| Neuroprotective effect of combination therapy of glatiramer acetate and epigallocatechin-3-gallate in neuroinflammation | Q34055604 | ||
| Oxidative stress, mitochondrial damage and neurodegenerative diseases | Q34094532 | ||
| A review of the neural mechanisms of action and clinical efficiency of riluzole in treating amyotrophic lateral sclerosis: what have we learned in the last decade? | Q34104378 | ||
| Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons. | Q34170853 | ||
| Axon physiology | Q34181026 | ||
| A randomized controlled phase II trial of riluzole in early multiple sclerosis | Q34286809 | ||
| Brain white matter damage in aging and cognitive ability in youth and older age. | Q34357262 | ||
| The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis. | Q34468304 | ||
| The gut microbiome and the brain | Q34652493 | ||
| Programmed cell death in amyotrophic lateral sclerosis | Q34831541 | ||
| Riluzole stimulates BDNF release from human platelets | Q34988697 | ||
| What is myelin? | Q35001588 | ||
| White matter injury, neural connectivity and the pathophysiology of psychiatric disorders | Q35011657 | ||
| Amyotrophic lateral sclerosis: progress and prospects for treatment | Q35048032 | ||
| Cellular mechanisms of toll-like receptor-3 activation in the thalamus are associated with white matter injury in the developing brain | Q35081704 | ||
| Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis - vulnerability of lower motor neurons to proximal excitotoxicity | Q35144020 | ||
| Gut microbiome and multiple sclerosis. | Q35245013 | ||
| An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy. | Q35246605 | ||
| Excitotoxicity mediated by non-NMDA receptors causes distal axonopathy in long-term cultured spinal motor neurons. | Q39100374 | ||
| Neuron-glia interactions underlie ALS-like axonal cytoskeletal pathology | Q39106329 | ||
| Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis | Q39200143 | ||
| Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production | Q39250599 | ||
| The neuroprotection exerted by memantine, minocycline and lithium, against neurotoxicity of CSF from patients with amyotrophic lateral sclerosis, is antagonized by riluzole | Q39290825 | ||
| Semaphorin 7A as a Potential Therapeutic Target for Multiple Sclerosis | Q39313856 | ||
| Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity | Q39492965 | ||
| Transplanted neural precursors enhance host brain-derived myelin regeneration | Q39762323 | ||
| Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis. | Q40165089 | ||
| Cerebrospinal Fluid from Sporadic Amyotrophic Lateral Sclerosis Patients Induces Mitochondrial and Lysosomal Dysfunction. | Q40233562 | ||
| Differential activation of ER stress pathways in myelinating cerebellar tracts. | Q40616916 | ||
| Directional guidance of oligodendroglial migration by class 3 semaphorins and netrin-1. | Q40717787 | ||
| Prevention of motoneuron death by adenovirus-mediated neurotrophic factors | Q41113386 | ||
| Chronic inhibitory effect of riluzole on trophic factor production | Q41464979 | ||
| Effects of dexpramipexole on brain mitochondrial conductances and cellular bioenergetic efficiency | Q42153700 | ||
| Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis | Q42266182 | ||
| Pramipexole, a Dopamine D2/D3 Receptor-Preferring Agonist, Prevents Experimental Autoimmune Encephalomyelitis Development in Mice. | Q42487975 | ||
| Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system | Q42594603 | ||
| Effects of pioglitazone on diffusion tensor imaging indices in multiple sclerosis patients | Q43167015 | ||
| Specific induction of Akt3 in spinal cord motor neurons is neuroprotective in a mouse model of familial amyotrophic lateral sclerosis. | Q43551571 | ||
| Riluzole suppresses experimental autoimmune encephalomyelitis: implications for the treatment of multiple sclerosis | Q44616100 | ||
| Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients. | Q44848574 | ||
| Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study | Q45298177 | ||
| Sexual dimorphism in ALS: exploring gender-specific neuroimaging signatures. | Q45911042 | ||
| A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice | Q46070173 | ||
| Hypoxia-Induced Iron Accumulation in Oligodendrocytes Mediates Apoptosis by Eliciting Endoplasmic Reticulum Stress. | Q46677308 | ||
| The effect of epigallocatechin gallate on suppressing disease progression of ALS model mice | Q46852629 | ||
| Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor | Q47316873 | ||
| Clinical, cognitive, and behavioural correlates of white matter damage in progressive supranuclear palsy | Q47907955 | ||
| Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle | Q48019378 | ||
| BDNF Serum Levels with Respect to Multidimensional Assessment in Amyotrophic Lateral Sclerosis | Q48066807 | ||
| Is riluzole a potential therapy for Rett syndrome? | Q48085997 | ||
| Are multiple sclerosis and amyotrophic lateral sclerosis autoimmune disorders of endogenous vasoactive neuropeptides? | Q48130371 | ||
| AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS. | Q48444548 | ||
| Up-regulated methyl CpG binding protein-2 in intractable temporal lobe epilepsy patients and a rat model | Q48469869 | ||
| Transplanted modified muscle progenitor cells expressing a mixture of neurotrophic factors delay disease onset and enhance survival in the SOD1 mouse model of ALS. | Q48480002 | ||
| White matter damage of patients with Alzheimer's disease correlated with the decreased cognitive function | Q48584283 | ||
| White matter pathology in ALS and lower motor neuron ALS variants: a diffusion tensor imaging study using tract-based spatial statistics | Q48651223 | ||
| Riluzole exerts central and peripheral modulating effects in amyotrophic lateral sclerosis. | Q48726185 | ||
| Tissue damage within normal appearing white matter in early multiple sclerosis: assessment by the ratio of T1- and T2-weighted MR image intensity | Q48737508 | ||
| Cognitive functions and white matter tract damage in amyotrophic lateral sclerosis: a diffusion tensor tractography study | Q48827615 | ||
| Brain MR Imaging in Patients with Lower Motor Neuron-Predominant Disease. | Q48846499 | ||
| Time and dose dependent effects of oxidative stress induced by cumene hydroperoxide in neuronal excitability of rat motor cortex neurons. | Q48906615 | ||
| T helper-17 activation dominates the immunologic milieu of both amyotrophic lateral sclerosis and progressive multiple sclerosis. | Q51001060 | ||
| Mitochondrial Dysfunction during the Early Stages of Excitotoxic Spinal Motor Neuron Degeneration in Vivo. | Q51531688 | ||
| Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis. | Q51751501 | ||
| Expression of semaphorin 3A, semaphorin 7A and their receptors in multiple sclerosis lesions. | Q52148517 | ||
| Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation. | Q52812058 | ||
| Hypothesis: a motor neuron toxin produced by a clostridial species residing in gut causes ALS. | Q53883308 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivatives | Q6937225 |
| P433 | issue | 4 | |
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| white matter | Q822050 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 4379-4392 | |
| P577 | publication date | 2017-08-07 | |
| 2017-10-01 | |||
| P1433 | published in | Molecular Medicine Reports | Q26842180 |
| P1476 | title | Implications of white matter damage in amyotrophic lateral sclerosis (Review). | |
| P478 | volume | 16 |
| Q41662736 | Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration? |
| Q64814767 | Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases |
| Q90294083 | Precentral degeneration and cerebellar compensation in amyotrophic lateral sclerosis: A multimodal MRI analysis |
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