| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/CMDC.201000100 |
| P8608 | Fatcat ID | release_jou5cfg4kzabtkm36vglmbmx2y |
| P698 | PubMed publication ID | 20491137 |
| P50 | author | Hans Bräuner-Osborne | Q37831020 |
| P2093 | author name string | Olivier Taboureau | |
| Flemming Steen Jørgensen | |||
| Søren Skovstrup | |||
| P2860 | cites work | Driving forces for ligand migration in the leucine transporter | Q46323912 |
| Proximity of transmembrane domains 1 and 3 of the gamma-aminobutyric acid transporter GAT-1 inferred from paired cysteine mutagenesis | Q46499559 | ||
| Inhibition of GABA uptake in rat brain slices by nipecotic acid, various isoxazoles and related compounds | Q48427274 | ||
| Selective amino acid substitutions convert the creatine transporter to a gamma-aminobutyric acid transporter. | Q51990209 | ||
| Structure-based rationalization of antitumor drugs mechanism of action by a MIF approach | Q58137126 | ||
| A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function | Q80035224 | ||
| Identification of a lithium interaction site in the gamma-aminobutyric acid (GABA) transporter GAT-1 | Q83938300 | ||
| LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake | Q24598921 | ||
| Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures | Q24655640 | ||
| Antidepressant binding site in a bacterial homologue of neurotransmitter transporters | Q27647095 | ||
| A competitive inhibitor traps LeuT in an open-to-out conformation | Q27653127 | ||
| VMD: visual molecular dynamics | Q27860554 | ||
| Comparative protein modelling by satisfaction of spatial restraints | Q27860866 | ||
| Synaptic uptake and beyond: the sodium- and chloride-dependent neurotransmitter transporter family SLC6 | Q28201669 | ||
| The interaction of the gamma-aminobutyric acid transporter GAT-1 with the neurotransmitter is selectively impaired by sulfhydryl modification of a conformationally sensitive cysteine residue engineered into extracellular loop IV | Q28202347 | ||
| Transmembrane domain I of the gamma-aminobutyric acid transporter GAT-1 plays a crucial role in the transition between cation leak and transport modes | Q28215794 | ||
| The aqueous accessibility in the external half of transmembrane domain I of the GABA transporter GAT-1 Is modulated by its ligands | Q28240888 | ||
| Tyrosine 140 of the gamma-aminobutyric acid transporter GAT-1 plays a critical role in neurotransmitter recognition | Q28241690 | ||
| Role of the conserved glutamine 291 in the rat gamma-aminobutyric acid transporter rGAT-1 | Q28569505 | ||
| Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters | Q29616590 | ||
| Structure-activity relationships of selective GABA uptake inhibitors. | Q33999938 | ||
| The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate | Q34062044 | ||
| GABAergic mechanisms in epilepsy | Q34087973 | ||
| Mechanism of chloride interaction with neurotransmitter:sodium symporters. | Q34664153 | ||
| GABAergic dysfunction in mood disorders. | Q35187929 | ||
| GABA, gamma-hydroxybutyric acid, and neurological disease | Q35189066 | ||
| Inhibition of gamma-aminobutyric acid uptake: anatomy, physiology and effects against epileptic seizures | Q35581505 | ||
| The GABA-glutamate connection in schizophrenia: which is the proximate cause? | Q35903154 | ||
| The M-Coffee web server: a meta-method for computing multiple sequence alignments by combining alternative alignment methods | Q35914038 | ||
| Identification of a chloride ion binding site in Na+/Cl -dependent transporters. | Q35921659 | ||
| Cloning and characterization of a functional human gamma-aminobutyric acid (GABA) transporter, human GAT-2. | Q40133028 | ||
| Elucidating conformational changes in the gamma-aminobutyric acid transporter-1. | Q42554749 | ||
| The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site | Q42909481 | ||
| Engineered Zn(2+) switches in the gamma-aminobutyric acid (GABA) transporter-1. Differential effects on GABA uptake and currents | Q43723442 | ||
| Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N- | Q44072243 | ||
| Intracellular domains of a rat brain GABA transporter that govern transport. | Q44854900 | ||
| Transmembrane domains I and II of the gamma-aminobutyric acid transporter GAT-4 contain molecular determinants of substrate specificity | Q44904916 | ||
| P433 | issue | 7 | |
| P304 | page(s) | 986-1000 | |
| P577 | publication date | 2010-07-01 | |
| P1433 | published in | ChemMedChem | Q2962252 |
| P1476 | title | Homology modelling of the GABA transporter and analysis of tiagabine binding | |
| P478 | volume | 5 |
| Q41439937 | A binding mode hypothesis of tiagabine confirms liothyronine effect on γ-aminobutyric acid transporter 1 (GAT1) |
| Q27300859 | A steered molecular dynamics study of binding and translocation processes in the GABA transporter |
| Q42605543 | An acidic amino acid transmembrane helix 10 residue conserved in the neurotransmitter:sodium:symporters is essential for the formation of the extracellular gate of the γ-aminobutyric acid (GABA) transporter GAT-1. |
| Q39768840 | An historical perspective on GABAergic drugs |
| Q86938754 | Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions |
| Q51167808 | Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents. |
| Q48144959 | Development of Non-GAT1-Selective Inhibitors: Challenges and Achievements |
| Q88679493 | Development of Positron Emission Tomography Radiotracers for the GABA Transporter 1 |
| Q40068020 | Different Binding Modes of Small and Large Binders of GAT1. |
| Q45093894 | Evidence for a Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters |
| Q61805435 | GRID-independent molecular descriptor analysis and molecular docking studies to mimic the binding hypothesis of γ-aminobutyric acid transporter 1 (GAT1) inhibitors |
| Q34769682 | Homology modeling of human γ-butyric acid transporters and the binding of pro-drugs 5-aminolevulinic acid and methyl aminolevulinic acid used in photodynamic therapy |
| Q90028050 | Immunomodulatory Action of Substituted 1,3,4-Thiadiazines on the Course of Myocardial Infarction |
| Q42143662 | Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures |
| Q60953415 | Modeling and Simulation of GAT1: A Mechanistic Investigation of the GABA Transport Process |
| Q55665570 | Pairwise structural comparison of tiagabine analogs gives new insights into their protein binding modes. |
| Q46111785 | Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters |
| Q41074219 | Sodium-assisted formation of binding and traverse conformations of the substrate in a neurotransmitter sodium symporter model |
| Q58750861 | Structure, Function, and Modulation of γ-Aminobutyric Acid Transporter 1 (GAT1) in Neurological Disorders: A Pharmacoinformatic Prospective |
| Q38572969 | Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the 5-HT transporter |
Search more.