Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study

scientific article published on 13 July 2014

Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PSC.2675
P698PubMed publication ID25044713
P5875ResearchGate publication ID263931924

P50authorSubbulakshmi ChidambaramQ42704828
P2093author name stringSulochana Konerirajapuram Natarajan
Arun Mohankumar
Bhuvanasundar Renganathan
Coral Karunakaran
P2860cites workThe tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.Q42831276
The catalytic function of bovine lysyl oxidase in the absence of copperQ43632091
Effects of lipoxin A(4) on CoCl(2)-induced angiogenesis and its possible mechanisms in human umbilical vein endothelial cellsQ43675495
Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis.Q46516361
Lysyl oxidase activity in the ocular tissues and the role of LOX in proliferative diabetic retinopathy and rhegmatogenous retinal detachmentQ46529839
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanismQ46853176
Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesisQ27026936
Tumor angiogenesis: therapeutic implicationsQ27860595
Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cellQ28208372
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasisQ28236828
The cross-linking of collagen and elastin: enzymatic conversion of lysine in peptide linkage to alpha-aminoadipic-delta-semialdehyde (allysine) by an extract from boneQ28251134
Lysyl oxidase mediates hypoxic control of metastasisQ28271667
Mechanisms of angiogenesis and arteriogenesisQ29617257
The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cellsQ30439639
Vascular endothelial growth factor as an anti-angiogenic target for cancer therapyQ30455612
Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS.Q31011527
Binding of copper (II) ion to an Alzheimer's tau peptide as revealed by MALDI-TOF MS, CD, and NMR.Q33218167
Thalidomide attenuates nitric oxide-driven angiogenesis by interacting with soluble guanylyl cyclaseQ33569519
Matrix metalloproteinases in angiogenesis: a moving target for therapeutic interventionQ33606833
Nitric oxide and angiogenesisQ34178838
Lysyl oxidase: properties, regulation and multiple functions in biologyQ34462312
Copper and angiogenesis: unravelling a relationship key to cancer progressionQ34503515
A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samplesQ34520249
Endothelial cell migration during angiogenesisQ34613912
CTR1 silencing inhibits angiogenesis by limiting copper entry into endothelial cellsQ34988260
Therapeutic peptidesQ35587596
Copper-induced activation of aortic lysyl oxidase in vivoQ35983980
Properties and Function of Lysyl OxidaseQ36520735
Paradoxical roles for lysyl oxidases in cancer--a prospectQ36807572
The rationale for targeting the LOX family in cancerQ38027412
Identification of the copper-binding ligands of lysyl oxidase.Q39614826
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis.Q39898008
Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.Q40514759
Copper is required for cobalt-induced transcriptional activity of hypoxia-inducible factor-1.Q42717951
Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma.Q42720975
P433issue11
P304page(s)837-849
P577publication date2014-07-13
P1433published inJournal of Peptide ScienceQ3186932
P1476titlePeptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study
P478volume20

Reverse relations

cites work (P2860)
Q57150248Authors' Response
Q38723997Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer
Q47405880Peptides derived from histidine and methionine-rich regions of copper transporter 1 exhibit anti-angiogenic property by chelating extracellular Cu.

Search more.