| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Philip C. Trackman | Q40642250 |
| P2860 | cites work | The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells | Q24301022 |
| The lysyl oxidase propeptide interacts with the receptor-type protein tyrosine phosphatase kappa and inhibits β-catenin transcriptional activity in lung cancer cells | Q24307235 | ||
| Lysyl oxidase-like 2 deaminates lysine 4 in histone H3 | Q24311943 | ||
| A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression | Q24314451 | ||
| Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane | Q24321781 | ||
| Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche | Q24606366 | ||
| Matrix crosslinking forces tumor progression by enhancing integrin signaling | Q24646370 | ||
| Further insight into the mechanism of stereoselective proton abstraction by bacterial copper amine oxidase | Q27651200 | ||
| Detection of the reaction intermediates catalyzed by a copper amine oxidase | Q27666349 | ||
| Lysyl oxidases: a novel multifunctional amine oxidase family | Q28201099 | ||
| Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell | Q28208372 | ||
| A molecular role for lysyl oxidase in breast cancer invasion | Q28216721 | ||
| RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis | Q28236828 | ||
| Elastic fiber homeostasis requires lysyl oxidase-like 1 protein | Q28240976 | ||
| Characterization of the native lysine tyrosylquinone cofactor in lysyl oxidase by Raman spectroscopy | Q28253795 | ||
| Structural and catalytic properties of copper in lysyl oxidase | Q28259509 | ||
| 67 laminin receptor promotes the malignant potential of tumour cells up-regulating lysyl oxidase-like 2 expression in cholangiocarcinoma | Q38998711 | ||
| Regulation of heterochromatin transcription by Snail1/LOXL2 during epithelial-to-mesenchymal transition | Q39062720 | ||
| LOXL2 expression is associated with invasiveness and negatively influences survival in breast cancer patients. | Q39112374 | ||
| Lysyl oxidase-like-2 promotes tumour angiogenesis and is a potential therapeutic target in angiogenic tumours | Q39130025 | ||
| Brief report: lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis | Q39244065 | ||
| Nonpeptidyl amine inhibitors are substrates of lysyl oxidase | Q39264349 | ||
| The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms | Q39451293 | ||
| Identification of the copper-binding ligands of lysyl oxidase. | Q39614826 | ||
| Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment | Q39659310 | ||
| Lysyl oxidase silencing impairs keratinocyte differentiation in a reconstructed-epidermis model. | Q39660303 | ||
| Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway | Q39822163 | ||
| Lysyl oxidase propeptide inhibits prostate cancer cell growth by mechanisms that target FGF-2-cell binding and signaling. | Q39825713 | ||
| Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells | Q39866831 | ||
| Functional analysis of the 5' flanking domain of the LOXL4 gene in head and neck squamous cell carcinoma cells. | Q39925767 | ||
| Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas | Q39971722 | ||
| LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer | Q40141667 | ||
| Selective upregulation and amplification of the lysyl oxidase like-4 (LOXL4) gene in head and neck squamous cell carcinoma | Q40160044 | ||
| Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice. | Q40174932 | ||
| Lysyl oxidase propeptide stimulates osteoblast and osteoclast differentiation and enhances PC3 and DU145 prostate cancer cell effects on bone in vivo | Q40251892 | ||
| Lysyl oxidase regulates actin filament formation through the p130(Cas)/Crk/DOCK180 signaling complex | Q40324343 | ||
| Sex-Linked Skeletal Phenotype of Lysyl Oxidase Like-1 Mutant Mice. | Q40354992 | ||
| Expression of lysyl oxidase isoforms in MC3T3-E1 osteoblastic cells. | Q40470613 | ||
| The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. | Q40531209 | ||
| A role for lysyl oxidase regulation in the control of normal collagen deposition in differentiating osteoblast cultures | Q40557286 | ||
| Alternatively spliced lysyl oxidase-like 4 isoforms have a pro-metastatic role in cancer | Q38323507 | ||
| Modulation of lysyl oxidase-like 2 enzymatic activity by an allosteric antibody inhibitor | Q38344322 | ||
| Novel combination of collagen dynamics analysis and transcriptional profiling reveals fibrosis-relevant genes and pathways | Q38490432 | ||
| Lysyl oxidase promotes epithelial-to-mesenchymal transition during paraquat-induced pulmonary fibrosis | Q38811599 | ||
| Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma. | Q38826075 | ||
| Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide | Q38841862 | ||
| LOXL2 Is Highly Expressed in Cancer-Associated Fibroblasts and Associates to Poor Colon Cancer Survival. | Q38849770 | ||
| Tumour-suppressive microRNA-29s directly regulate LOXL2 expression and inhibit cancer cell migration and invasion in renal cell carcinoma | Q38861461 | ||
| Orthotopic non-metastatic and metastatic oral cancer mouse models | Q38909572 | ||
| Identification of a novel lysyl oxidase-like 2 alternative splicing isoform, LOXL2 Δe13, in esophageal squamous cell carcinoma | Q38951237 | ||
| Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer | Q38965504 | ||
| Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma. | Q38973071 | ||
| Effects of tumor-suppressor lysyl oxidase propeptide on prostate cancer xenograft growth and its direct interactions with DNA repair pathways | Q38989588 | ||
| The Pro-regions of lysyl oxidase and lysyl oxidase-like 1 are required for deposition onto elastic fibers | Q28279129 | ||
| Metalloproteinase activity secreted by fibrogenic cells in the processing of prolysyl oxidase. Potential role of procollagen C-proteinase | Q28279434 | ||
| Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis | Q28280138 | ||
| The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer | Q28304399 | ||
| Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice | Q28510969 | ||
| Lysyl oxidase and P-ATPase-7A expression during embryonic development in the rat | Q28577158 | ||
| Lysyl oxidase-like-2 (LOXL2) is a major isoform in chondrocytes and is critically required for differentiation | Q28587970 | ||
| Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice | Q28854384 | ||
| Metalloproteinase Activity Secreted by Fibrogenic Cells in the Processing of Prolysyl Oxidase | Q29544584 | ||
| Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide | Q30009534 | ||
| Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence | Q33500041 | ||
| The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1 | Q33673803 | ||
| Lysyl oxidase propeptide inhibits FGF-2-induced signaling and proliferation of osteoblasts | Q33748104 | ||
| An Impermeant Ganetespib Analog Inhibits Extracellular Hsp90-Mediated Cancer Cell Migration that Involves Lysyl Oxidase 2-like Protein | Q33820289 | ||
| Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures | Q33943363 | ||
| Central nervous system, uterus, heart, and leukocyte expression of the LOXL3 gene, encoding a novel lysyl oxidase-like protein | Q33949334 | ||
| High glucose-induced altered basement membrane composition and structure increases trans-endothelial permeability: implications for diabetic retinopathy | Q33968771 | ||
| Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma | Q34005664 | ||
| Intra- and extracellular enzymes of collagen biosynthesis as biological and chemical targets in the control of fibrosis | Q34038442 | ||
| Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis | Q34068215 | ||
| Cloning and characterization of a fifth human lysyl oxidase isoenzyme: the third member of the lysyl oxidase-related subfamily with four scavenger receptor cysteine-rich domains | Q34100206 | ||
| Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts | Q34170606 | ||
| Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivo | Q34187677 | ||
| Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas | Q34197948 | ||
| Transforming growth factor alpha is a critical mediator of radiation lung injury | Q34213244 | ||
| High glucose increases lysyl oxidase expression and activity in retinal endothelial cells: mechanism for compromised extracellular matrix barrier function | Q34355294 | ||
| LOXL3, encoding lysyl oxidase-like 3, is mutated in a family with autosomal recessive Stickler syndrome | Q34461814 | ||
| N-acetyl-seryl-aspartyl-lysyl-proline reduces cardiac collagen cross-linking and inflammation in angiotensin II-induced hypertensive rats | Q34554693 | ||
| A tissue-specific variant of the human lysyl oxidase-like protein 3 (LOXL3) functions as an amine oxidase with substrate specificity | Q34571275 | ||
| Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells | Q34764399 | ||
| Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. | Q34784159 | ||
| Failure of elastic fiber homeostasis leads to pelvic floor disorders | Q35087974 | ||
| Control of megakaryocyte expansion and bone marrow fibrosis by lysyl oxidase | Q35144992 | ||
| Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension | Q35169710 | ||
| A novel function for lysyl oxidase in pluripotent mesenchymal cell proliferation and relevance to inflammation-associated osteopenia | Q35196329 | ||
| The copper chelator tetrathiomolybdate regressed bleomycin-induced pulmonary fibrosis in mice, by reducing lysyl oxidase expressions | Q35370201 | ||
| Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression. | Q35527142 | ||
| Prevention of phenytoin-induced gingival overgrowth by lovastatin in mice | Q35669027 | ||
| Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-κB signaling | Q35688339 | ||
| The Role of LOX and LOXL2 in the Pathogenesis of an Experimental Model of Choroidal Neovascularization. | Q35741400 | ||
| Identifying specific proteins involved in eggshell membrane formation using gene expression analysis and bioinformatics. | Q35809137 | ||
| Mechanism of post-translational quinone formation in copper amine oxidases and its relationship to the catalytic turnover | Q35974365 | ||
| Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy. | Q36000813 | ||
| Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea | Q36076679 | ||
| Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway | Q36093199 | ||
| Lysyl oxidase-like-1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved | Q36126637 | ||
| Tetrathiomolybdate inhibits mitochondrial complex IV and mediates degradation of hypoxia-inducible factor-1α in cancer cells | Q36163903 | ||
| Molecular Mechanism Responsible for Fibronectin-controlled Alterations in Matrix Stiffness in Advanced Chronic Liver Fibrogenesis. | Q36419309 | ||
| Histologic changes during selenite cataractogenesis: a light microscopy study | Q36496086 | ||
| Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma | Q36498118 | ||
| Properties and Function of Lysyl Oxidase | Q36520735 | ||
| Lysyl oxidase: an oxidative enzyme and effector of cell function | Q36565804 | ||
| Up-regulation of lysyl oxidase in spontaneous revertants of H-ras-transformed rat fibroblasts | Q36697240 | ||
| LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis | Q36903532 | ||
| LOXL4 is induced by transforming growth factor β1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling. | Q36978251 | ||
| The lysyl oxidase pro-peptide attenuates fibronectin-mediated activation of focal adhesion kinase and p130Cas in breast cancer cells | Q37041619 | ||
| The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase. | Q37126990 | ||
| MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal transition (EMT) phenotype and are highly invasive in vitro. | Q37233956 | ||
| A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer | Q37312261 | ||
| Tumor-secreted LOXL2 activates fibroblasts through FAK signaling | Q37324753 | ||
| Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03. | Q37347497 | ||
| The role of lysyl oxidase-like 2 in the odontogenic differentiation of human dental pulp stem cells | Q37462233 | ||
| Disruption of the blood-aqueous barrier and lens abnormalities in mice lacking lysyl oxidase-like 1 (LOXL1). | Q37577216 | ||
| Vascular basement membrane thickening in diabetic retinopathy. | Q37798548 | ||
| The rationale for targeting the LOX family in cancer | Q38027412 | ||
| A new role for LOX and LOXL2 proteins in transcription regulation | Q38237959 | ||
| Dysregulation of Lysyl Oxidase Expression in Lesions and Endometrium of Women With Endometriosis | Q38299088 | ||
| Update on pseudoexfoliation syndrome pathogenesis and associations with intraocular pressure, glaucoma and systemic diseases. | Q38320827 | ||
| The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation | Q40811068 | ||
| Quantitative polymerase chain reaction of lysyl oxidase mRNA in malignantly transformed human cell lines demonstrates that their low lysyl oxidase activity is due to low quantities of its mRNA and low levels of transcription of the respective gene. | Q41295028 | ||
| Post-translational glycosylation and proteolytic processing of a lysyl oxidase precursor. | Q41628295 | ||
| Lysyl oxidase and rrg messenger RNA. | Q41669222 | ||
| Expression of Gene rrg Is Associated with Reversion of NIH 3Tt3 Transformed by LTR-c-H- ras | Q41724661 | ||
| Megakaryocyte polyploidy is inhibited by lysyl oxidase propeptide | Q41898229 | ||
| LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition. | Q41957208 | ||
| Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome | Q42580624 | ||
| Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study | Q42704767 | ||
| The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer. | Q42831276 | ||
| TGF-beta1 causes airway fibrosis and increased collagen I and III mRNA in mice | Q43059347 | ||
| Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy | Q43160577 | ||
| The catalytic function of bovine lysyl oxidase in the absence of copper | Q43632091 | ||
| Reaction pathway of bovine aortic lysyl oxidase | Q44181626 | ||
| Lysyl oxidase is required for vascular and diaphragmatic development in mice | Q44243394 | ||
| Lysyl oxidase-like 4 is alternatively spliced in an anatomic site-specific manner in tumors involving the serosal cavities | Q44963178 | ||
| Mitochondrial cytochrome c oxidase: mechanism of action and role in regulating oxidative phosphorylation | Q45417827 | ||
| A crosslinked cofactor in lysyl oxidase: redox function for amino acid side chains. | Q45946202 | ||
| Lysyl oxidase like-2 reinforces unsatisfactory ossification induced by bone morphogenetic protein-2: relating nanomechanical properties and molecular changes | Q46063004 | ||
| Lower urogenital tract anatomical and functional phenotype in lysyl oxidase like-1 knockout mice resembles female pelvic floor dysfunction in humans | Q46582486 | ||
| Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis | Q46611973 | ||
| The Formation of lysine tyrosylquinone (LTQ) is a self-processing reaction. Expression and characterization of a Drosophila lysyl oxidase | Q46674808 | ||
| Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanism | Q46853176 | ||
| LOXL2 Oxidizes Methylated TAF10 and Controls TFIID-Dependent Genes during Neural Progenitor Differentiation | Q47035968 | ||
| Disruption of collagen homeostasis can reverse established age-related myocardial fibrosis | Q50451339 | ||
| Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma. | Q50540766 | ||
| Lysyl oxidase-like 2 (LOXL2) and E47 EMT factor: novel partners in E-cadherin repression and early metastasis colonization. | Q50677852 | ||
| Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction. | Q50947326 | ||
| Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase? | Q51040164 | ||
| Lysyl oxidase promotes bleomycin-induced lung fibrosis through modulating inflammation. | Q51688171 | ||
| Lysyl oxidase modulates the osteoblast differentiation of primary mouse calvaria cells. | Q53189505 | ||
| Injury-Driven Stiffening of the Dermis Expedites Skin Carcinoma Progression. | Q53241307 | ||
| Deficient production of lysyl oxidase in cultures of malignantly transformed human cells. | Q53538666 | ||
| Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway. | Q54191996 | ||
| Down-regulation of lysyl oxidase-like 2 (LOXL2) is associated with disease progression in lung adenocarcinomas. | Q54376072 | ||
| Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. | Q54508335 | ||
| Ancestral LOXL1 variants are associated with pseudoexfoliation in Caucasian Australians but with markedly lower penetrance than in Nordic people | Q57252101 | ||
| Cloning of rat aorta lysyl oxidase cDNA: complete codons and predicted amino acid sequence [Erratum to document cited in CA112(25):230629x] | Q58029495 | ||
| Induction of lung lysyl oxidase activity and lysyl oxidase protein by exposure of rats to cadmium chloride: properties of the induced enzyme | Q58029508 | ||
| Comparative sensitivities of purified preparations of lysyl oxidase and other amine oxidases to active site-directed enzyme inhibitors | Q69374350 | ||
| Increased expression of lysyl oxidase in skin with scleroderma | Q70883119 | ||
| Mechanism of collagen network stabilization in human irreversible granulomatous liver fibrosis | Q71235024 | ||
| Lysyl oxidase copper-talon complex: a model | Q72232196 | ||
| The activity of lysyl oxidase in experimental hepatic fibrosis | Q72530120 | ||
| Reaction of aortic lysyl oxidase with beta-aminopropionitrile | Q72548394 | ||
| Regulation of lysyl oxidase, collagen, and connective tissue growth factor by TGF-beta1 and detection in human gingiva | Q73314005 | ||
| Differentially expressed genes associated with the metastatic phenotype in breast cancer | Q78244545 | ||
| LOXL4 as a selective molecular marker in primary and metastatic head/neck carcinoma | Q82658415 | ||
| Inhibition of aldosterone synthase (CYP11B2) by torasemide prevents atrial fibrosis and atrial fibrillation in mice | Q85319588 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 935-945 | |
| P577 | publication date | 2016-02-05 | |
| P1433 | published in | Expert Opinion on Therapeutic Targets | Q5421214 |
| P1476 | title | Lysyl Oxidase Isoforms and Potential Therapeutic Opportunities for Fibrosis and Cancer | |
| P478 | volume | 20 |
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