Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.

scientific article

Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONC.2012.202
P698PubMed publication ID22641216
P5875ResearchGate publication ID225068998

P50authorThomas R CoxQ47097322
Janine T. ErlerQ55299167
Ann-Marie BakerQ57599302
P2093author name stringG Lang
D Bird
P2860cites workActomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growthQ24613142
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Biomechanics and biophysics of cancer cellsQ34048694
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environmentQ36215812
A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growthQ37143147
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.Q37347497
The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growthQ39607305
Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumorsQ43864443
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanismQ46853176
High-resolution tensor MR elastography for breast tumour detection.Q52077047
The presence of a fibrotic focus is an independent predictor of early metastasis in lymph node-negative breast cancer patientsQ77212742
Exploiting glycation to stiffen and strengthen tissue equivalents for tissue engineeringQ77838590
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)1863-1868
P577publication date2012-05-28
P1433published inOncogeneQ1568657
P1476titleLysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
P478volume32

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