Measurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses

scientific article

Measurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1476-5381.1991.TB12357.X
P932PMC publication ID1908181
P698PubMed publication ID1912982
P5875ResearchGate publication ID21242972

P2093author name stringGreen AR
Baldwin HA
Murray TK
Cross AJ
Sarna GS
De Souza RJ
P2860cites workThe mechanism of tetrahydroaminoacridine-evoked release of endogenous 5-hydroxytryptamine and dopamine from rat brain tissue prismsQ28354362
9-Amino-1,2,3,4-tetrahydroacridine (THA) is a potent blocker of cardiac potassium channelsQ35755032
Drug treatments of dementiaQ38371116
Inhibitory effect of 1,2,3,4-tetrahydro-9-aminoacridine on the depolarization-induced release of GABA from cerebral cortexQ42144280
Correlation of brain levels of 9-amino-1,2,3,4-tetrahydroacridine (THA) with neurochemical and behavioral changesQ42193084
The cholinergic pharmacology of tetrahydroaminoacridine in vivo and in vitroQ42847596
Influence of tetrahydro-9-aminoacridine on excitatory amino acid releaseQ44130586
Excitatory actions of tetrahydro-9-aminoacridine (THA) on hippocampal pyramidal neuronsQ46223543
Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's diseaseQ48161693
Tetrahydroaminoacridine blocks voltage-dependent ion channels in hippocampal neuronsQ48195378
9-Amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease, inhibits acetylcholinesterase activity and slow outward K+ currentQ48208220
Monitoring the effect of a tryptophan load on brain indole metabolism in freely moving rats by simultaneous cerebrospinal fluid sampling and brain dialysisQ48505886
Tetrahydro-9-aminoacridine (THA) interacts with the phencyclidine (PCP) receptor site.Q51771071
Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type.Q52259713
Tetrahydroaminoacridine blocks potassium channels and inhibits sodium inactivation in Myxicola.Q54398592
Determination of tacrine hydrochloride in human serum by chloroform extraction, reversed-phase high-performance liquid chromatography and fluorimetric detectionQ68049023
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1946-1950
P577publication date1991-08-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleMeasurements of tacrine and monoamines in brain by in vivo microdialysis argue against release of monoamines by tacrine at therapeutic doses
P478volume103

Reverse relations

cites work (P2860)
Q48244513A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066.
Q40472033Clinical Pharmacokinetics of Tacrine
Q48360983Distribution of tacrine across the blood-brain barrier in awake, freely moving rats using in vivo microdialysis sampling
Q46965271Dose-related effects of the acetylcholinesterase inhibitor tacrine on cocaine and food self-administration in rats.
Q43690891Effect of distigmine bromide on the central cholinergic system
Q48707439Effects of R(−)-1-(benzo[b]thiophen-5-yl)-2-[2-(N,N-diethylamino) ethoxy]ethanol hydrochloride (T-588), a novel cognitive enhancer, on noradrenaline release in rat cerebral cortical slices
Q46092796Independent effects of cholinergic and serotonergic lesions on acetylcholine and serotonin release in the neocortex of the rat
Q52546994Metrifonate effects on acetylcholine and biogenic amines in rat cortex.
Q28378688Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine
Q40392124Tacrine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease
Q22242019The cholinergic hypothesis of Alzheimer's disease: a review of progress

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