Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.

scientific article published on 11 June 2012

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.25689
P698PubMed publication ID22383097
P5875ResearchGate publication ID221881753

P50authorJohn K. OlynykQ37830523
Kevin CroftQ56085649
P2093author name stringAnita C G Chua
Debbie Trinder
Ross M Graham
Janina E E Tirnitz-Parker
Eng K Gan
Roheeth D Delima
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Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liverQ28506594
A population-based study of the clinical expression of the hemochromatosis geneQ33872904
Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosisQ33894300
The importance of non-transferrin bound iron in disorders of iron metabolismQ34094818
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Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlationsQ36116795
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Iron-mediated inhibition of mitochondrial manganese uptake mediates mitochondrial dysfunction in a mouse model of hemochromatosis.Q36481958
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Pathophysiology of iron toxicity.Q40610814
Function of the hemochromatosis protein HFE: Lessons from animal modelsQ42619912
Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cellsQ43005719
Mitochondrial damage, cytotoxicity and apoptosis in iron-potentiated alcoholic liver fibrosis: amelioration by taurineQ46043125
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Cancer risk in patients with hereditary hemochromatosis and in their first-degree relativesQ47360264
Hepatic stellate cell activation in genetic haemochromatosis. Lobular distribution, effect of increasing hepatic iron and response to phlebotomy.Q50530429
HFE genotype in patients with hemochromatosis and other liver diseases.Q51562649
Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.Q54459192
Enhanced γ-Glutamyl Transpeptidase Expression and Selective Loss of CuZn Superoxide Dismutase in Hepatic Iron OverloadQ54975586
Autosomal-dominant hemochrom-atosis is associated with a mutation in the ferroportin (SLC11A3) geneQ59512946
Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosisQ61895889
Liver gene expression during chronic dietary iron overload in ratsQ67660492
Biochemical liver profile in hemochromatosis. A survey of 100 patientsQ70222548
1,N6-Ethenodeoxyadenosine and 3,N4-ethenodeoxycytidine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabellingQ72112941
Iron overload facilitates hepatic fibrosis in the rat alcohol/low-dose carbon tetrachloride modelQ72131178
Formation of 1,N6-ethenoadenine and 3,N4-ethenocytosine by lipid peroxidation products and nucleic acid basesQ72278048
Evidence for a sub-morphological inflammatory process in the liver in haemochromatosisQ73187936
Is there a threshold of hepatic iron concentration that leads to cirrhosis in C282Y hemochromatosis?Q73572635
An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometryQ74482358
Clinical and pathologic findings in hemochromatosis type 3 due to a novel mutation in transferrin receptor 2 geneQ78028899
Studies on intermediary iron metabolism. V. The measurement of non-haemoglobin tissue ironQ78619747
Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3Q80174432
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)585-593
P577publication date2012-06-11
P1433published inHepatologyQ15724398
P1476titleDisruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice
P478volume56

Reverse relations

cites work (P2860)
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