Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma.

scientific article published on April 1995

Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JNCI/87.7.506
P698PubMed publication ID7707437

P50authorSteve Charnock-JoneQ57177791
Andrew Marck SharkeyQ41633924
P2093author name stringK A Wright
S K Smith
J McLaren
P J Barker
P R Twentyman
C A Boocock
P4510describes a project that usesOV17RQ54936883
OV25RQ54936887
OV7Q54936905
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
cell lineQ21014462
P304page(s)506-516
P577publication date1995-04-01
P1433published inJournal of the National Cancer InstituteQ400279
P1476titleExpression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma
P478volume87

Reverse relations

described by source (P1343)
Q54936883OV17R
Q54936887OV25R
Q54936898OV56
Q54936899OV58
Q54936905OV7

cites work (P2860)
Q47743059A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse
Q77733808A novel gene delivery system targeting cells expressing VEGF receptors
Q30429122Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trial
Q75196511All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells
Q38349912Angiogenesis and the expression of vascular endothelial growth factor in endometrium and placenta
Q36746626Angiogenesis in cancer
Q33919078Angiogenesis in epithelian ovarian cancer
Q73954429Angiogenesis in ovarian carcinoma: a formidable biomarker
Q73760972Angiogenesis in primary and metastatic epithelial ovarian carcinoma
Q34461788Angiogenesis inhibitors in the treatment of lung cancer
Q36431516Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia
Q33825273Angiogenesis of the ovary
Q53376658Angiogenetic protooncogene ets-1 induced neovascularization is involved in the metastatic process of testicular germ cell tumors.
Q37739569Anti-tumour activity of tivozanib, a pan-inhibitor of VEGF receptors, in therapy-resistant ovarian carcinoma cells
Q40677359Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4.
Q36134259Association of vascular endothelial growth factor expression with intratumoral microvessel density and tumour cell proliferation in human epidermoid lung carcinoma
Q74505899Association of vascular endothelial growth factor expression with tumor angiogenesis, survival and thymidine phosphorylase/platelet-derived endothelial cell growth factor expression in human colorectal cancer
Q37159495Bevacizumab for the treatment of advanced non-small-cell lung cancer
Q73112514Cell-retained isoforms of vascular endothelial growth factor (VEGF) are correlated with poor prognosis in osteosarcoma
Q33610969Chronic cocaine induces HIF-VEGF pathway activation along with angiogenesis in the brain
Q36089989Cisplatin plus paclitaxel and maintenance of bevacizumab on tumour progression, dissemination, and survival of ovarian carcinoma xenograft models
Q36623505Clinical implications of expression of vascular endothelial growth factor in metastatic lesions of ovarian cancers
Q73614411Clinical relevance of Flt1 and Tie1 angiogenesis receptors expression in B-cell chronic lymphocytic leukemia (CLL)
Q41372744Clinical significance of the determination of angiogenic factors
Q45798976Clinicopathological significance of hypoxia-inducible factor-1 alpha (HIF-1α) expression in gastric cancer
Q59799628Combination of triapine, olaparib, and cediranib suppresses progression of BRCA-wild type and PARP inhibitor-resistant epithelial ovarian cancer
Q34023344Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy
Q61896370Comparative analysis of loss of heterozygosity and expression profi le in normal tissue, DCIS and invasive breast cancer
Q36292714Concentration of vascular endothelial growth factor (VEGF) in the serum of patients with suspected ovarian cancer
Q36622433Concentration of vascular endothelial growth factor in the tumour tissue as a prognostic factor of soft tissue sarcomas
Q48909870Contrast-enhanced ultrasonography for assessment of tumor vascularity in hepatocellular carcinoma
Q41778639Correlation of vascular endothelial growth factor expression with fibroblast growth factor-8 expression and clinico-pathologic parameters in human prostate cancer
Q38137570Current and future biologic markers for disease progression and relapse in testicular germ cell tumors: a review
Q41111895Cytokines in tumour growth, migration and metastasis
Q34129693DNA methylation regulates expression of VEGF-R2 (KDR) and VEGF-R3 (FLT4).
Q46122468Differential expression of VEGF ligands and receptors in prostate cancer
Q44251620Differential expression of VEGF receptors in adrenal atrophy induced by dexamethasone: a protective role of ACTH.
Q36293040Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E.
Q38431573Disease-free and overall survival at 3.5 years for neoadjuvant bevacizumab added to docetaxel followed by fluorouracil, epirubicin and cyclophosphamide, for women with HER2 negative early breast cancer: ARTemis Trial
Q78704136Distribution of vascular endothelial growth factor (VEGF) in prostate disease
Q35098085Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment
Q34748791Double suicide genes driven by kinase domain insert containing receptor promoter selectively kill human lung cancer cells
Q39419250Down-modulation of TNFSF15 in ovarian cancer by VEGF and MCP-1 is a pre-requisite for tumor neovascularization
Q35922535ETS-1 protein regulates vascular endothelial growth factor-induced matrix metalloproteinase-9 and matrix metalloproteinase-13 expression in human ovarian carcinoma cell line SKOV-3.
Q40593958Effects of vascular endothelial growth factor expression on pathological characteristics and prognosis of osteosarcoma
Q35560094Effusion cytology in ovarian cancer: new molecular methods as aids to diagnosis and prognosis
Q44611371Endometriosis-associated ovarian carcinoma: differential expression of vascular endothelial growth factor and estrogen/progesterone receptors
Q48122829Enzymatic rationale and preclinical support for a potent protein kinase C beta inhibitor in cancer therapy
Q40612609Estrogen regulation of vascular endothelial growth factor gene expression in ZR-75 breast cancer cells through interaction of estrogen receptor alpha and SP proteins
Q36865053Evaluation of potentially predictive markers for anti-angiogenic therapy with sunitinib in recurrent ovarian cancer patients
Q79661656Evaluation of serum vascular endothelial growth factor (VEGF) and microvessel density (MVD) as prognostic indicators in carcinoma breast
Q36777298Evaluation of the angiogenesis inhibitor KR-31831 in SKOV-3 tumor-bearing mice using (64)Cu-DOTA-VEGF(121) and microPET.
Q37347027Evidence of a genetic link between endometriosis and ovarian cancer
Q43997195Expression and endocytosis of VEGF and its receptors in human colonic vascular endothelial cells
Q73668795Expression of angiogenesis factors in monolayer culture, multicellular spheroid and in vivo transplanted tumor by human ovarian cancer cell lines
Q34678882Expression of sorafenib targets in melanoma patients treated with carboplatin, paclitaxel and sorafenib
Q36671720Expression of the VEGF and angiopoietin genes in endometrial atypical hyperplasia and endometrial cancer.
Q78128696Expression of vascular endothelial growth factor (VEGF) and its receptors in human neuroblastoma
Q36431375Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: correlation with clinicopathology and patient survival, and analysis of serum VEGF levels
Q73294135Expression of vascular endothelial growth factor and its receptors in the rhesus monkey (Macaca mulatta) endometrium and placenta during early pregnancy
Q53425142Expression of vascular endothelial growth factor in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis.
Q50950759Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: an immunohistochemical study.
Q73289328Expression of vascular endothelial growth factor isoforms and platelet-derived endothelial cell growth factor in bladder cancer
Q42477154Expression of vascular endothelial growth factor receptors in human prostate cancer
Q53346120Expression of vascular endothelial growth factor related to 72-kilodalton metalloproteinase immunostaining in patients with serous ovarian tumors.
Q35746653Expresson of vascular endothelial growth factor, its receptors (FLT-1, KDR) and TSP-1 related to microvessel density and patient outcome in vertical growth phase melanomas
Q24608649GADD45 proteins: central players in tumorigenesis
Q36922247Gene therapy of gynaecological diseases
Q36464907Gene transfer approaches for gynecological diseases
Q35748149Generation of a syngeneic mouse model to study the effects of vascular endothelial growth factor in ovarian carcinoma.
Q41086267Hepatocyte growth factor stimulates motility, chemotaxis and mitogenesis in ovarian carcinoma cells expressing high levels of c-met
Q36608597High efficacy of CpG-ODN, cetuximab and cisplatin combination for very advanced ovarian xenograft tumors
Q35562421Identification of common mechanisms between endometriosis and ovarian cancer.
Q38710046Imaging-guided delivery of RNAi for anticancer treatment
Q34901858Immunization with synthetic VEGF peptides in ovarian cancer
Q30750084Immunolocalisation of the VEGF receptors FLT-1, KDR, and FLT-4 in diabetic retinopathy
Q42794629Importance of vascular phenotype by basic fibroblast growth factor, and influence of the angiogenic factors basic fibroblast growth factor/fibroblast growth factor receptor-1 and ephrin-A1/EphA2 on melanoma progression
Q40580539In vivo inhibition of tumor angiogenesis by a soluble VEGFR-2 fragment
Q43184381Incisor degeneration in rats induced by vascular endothelial growth factor/fibroblast growth factor receptor tyrosine kinase inhibition
Q44719653Induction of protein growth factor systems in the ovaries of transgenic mice overexpressing human type 2 lysophosphatidic acid G protein-coupled receptor (LPA2).
Q47273203Inhibition of both the autocrine and the paracrine growth of human leukemia with a fully human antibody directed against vascular endothelial growth factor receptor 2.
Q39880781Inhibition of cell proliferation, vascular endothelial growth factor and tumor growth by albendazole
Q31135653Inhibition of human leukemia in an animal model with human antibodies directed against vascular endothelial growth factor receptor 2. Correlation between antibody affinity and biological activity
Q22254113Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins
Q40211907Integrin regulation by vascular endothelial growth factor in human brain microvascular endothelial cells: role of alpha6beta1 integrin in angiogenesis
Q36824041Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene
Q45862137Intraperitoneal gene therapy by rAAV provides long-term survival against epithelial ovarian cancer independently of survivin pathway
Q38152755Intravenous aflibercept in patients with platinum-resistant, advanced ovarian cancer: results of a randomized, double-blind, phase 2, parallel-arm study.
Q33897202Kinase inhibitors in cancer therapy: a look ahead
Q40416729LPA-induced epithelial ovarian cancer (EOC) in vitro invasion and migration are mediated by VEGF receptor-2 (VEGF-R2).
Q81101590Localization of the VEGF and angiopoietin genes in uterine carcinosarcoma
Q36722080Loss of ovarian function promotes angiogenesis in human ovarian carcinoma
Q38252667Macrophage colony-stimulating factor and cancer: a review
Q35903683Malignant effusions: from diagnosis to biology
Q46830786Micro-vessel density and the expression of vascular endothelial growth factor (VEGF) and platelet-derived endothelial cell growth factor (PdEGF) in classical Hodgkin lymphoma (HL).
Q35842085Molecular determinants of ovarian cancer plasticity
Q36904860Novel agents in ovarian cancer.
Q39692519Novel compounds with antiangiogenic and antiproliferative potency for growth control of testicular germ cell tumours
Q35085430Novel function for vascular endothelial growth factor receptor-1 on epidermal keratinocytes
Q37024446Novel soluble Flt-1 isoforms in plasma and cultured placental explants from normotensive pregnant and preeclamptic women.
Q28543021Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes
Q40412257Ovarian carcinoma cells and IL-1beta-activated human peritoneal mesothelial cells are possible sources of vascular endothelial growth factor in inflammatory and malignant peritoneal effusions
Q34781970Overexpression of Tumor Vascular Endothelial Growth Factor A May Portend an Increased Likelihood of Progression in a Phase II Trial of Bevacizumab and Erlotinib in Resistant Ovarian Cancer
Q34722935Pathological significance of vascular endothelial growth factor A isoform expression in human cancer
Q36791086Primary extraosseous Ewing sarcoma of the lung in children
Q36617666Production of VEGF and expression of the VEGF receptors Flt-1 and KDR in primary cultures of epithelial and stromal cells derived from breast tumours
Q36621710Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma
Q36077140Prognostic significance of vascular endothelial growth factor serum determination in women with ovarian cancer
Q36621924Prognostic value of vascular endothelial growth factor (VEGF) in head and neck squamous cell carcinomas
Q73670868Prognostic value of vascular endothelial growth factor expression in colorectal cancer patients
Q53664103Prognostic value of vascular endothelial growth factor in Stage IB carcinoma of the uterine cervix.
Q39384319Promoter methylation status of VEGF receptor genes: a possible epigenetic biomarker to anticipate the efficacy of intracellular-acting VEGF-targeted drugs in cancer cells.
Q33770947Purinergic mechanisms in breast cancer support intravasation, extravasation and angiogenesis
Q73226531Quantification of VEGF mRNA expression in non-small cell lung cancer using a real-time quantitative reverse transcription-PCR assay and a comparison with quantitative competitive reverse transcription-PCR
Q28480617Quercetin-4'-O-β-D-glucopyranoside (QODG) inhibits angiogenesis by suppressing VEGFR2-mediated signaling in zebrafish and endothelial cells
Q40884078Release and complex formation of soluble VEGFR-1 from endothelial cells and biological fluids
Q36292232Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology.
Q45873437Retroviral hybrid LTR vector strategy: functional analysis of LTR elements and generation of endothelial cell specificity
Q35829525Role of endothelin-1 in neovascularization of ovarian carcinoma
Q41060744Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines
Q35753569Role of vascular endothelial growth factor in ovarian cancer: inhibition of ascites formation by immunoneutralization
Q33771212Role of vascular endothelial growth factor inhibitors in the treatment of gynecologic malignancies
Q39628302SR16388: a steroidal antiangiogenic agent with potent inhibitory effect on tumor growth in vivo
Q36394925Science and technology of the emerging nanomedicines in cancer therapy: A primer for physicians and pharmacists
Q38472672Serum vascular endothelial growth factor is a candidate biomarker of metastatic tumor response to ex vivo gene therapy of renal cell cancer
Q35954103Significance of vascular endothelial growth factor in growth and peritoneal dissemination of ovarian cancer
Q34774019Soluble flt-1 and the angiopoietins in the development and regulation of placental vasculature
Q84491268Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study
Q24315888Src homology 2 (SH2) domain containing protein tyrosine phosphatase-1 (SHP-1) dephosphorylates VEGF Receptor-2 and attenuates endothelial DNA synthesis, but not migration
Q34878868Targeted therapies in epithelial ovarian cancer: Molecular mechanisms of action
Q39747275Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Q24307613The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells
Q22010690The effects of angiogenic growth factors on extravillous trophoblast invasion and motility
Q36623444The expression of vascular endothelial growth factor C and its receptors in non-small cell lung cancer
Q33706710The rationale and future potential of angiogenesis inhibitors in neoplasia
Q37937859The role of targeted therapy in ovarian cancer
Q36627750The tumor microenvironment: key to early detection
Q35011885Therapies directed at vascular endothelial growth factor
Q64229289Thymoquinone, an Active Constituent of Black Seed Attenuates CCl4 Induced Liver Injury in Mice via Modulation of Antioxidant Enzymes, PTEN, P53 and VEGF Protein
Q64997568Tubeimoside-1 inhibits the proliferation and metastasis by promoting miR-126-5p expression in non-small cell lung cancer cells.
Q37308766Tumor cell expression of vascular endothelial growth factor receptor 2 is an adverse prognostic factor in patients with squamous cell carcinoma of the lung
Q30359568Ultrasound Molecular Imaging of Angiogenesis Using Vascular Endothelial Growth Factor-Conjugated Microbubbles.
Q35093616VEGF blocking therapy in the treatment of cancer
Q38293320VEGF expression and enhanced production by gonadotropins in ovarian epithelial tumors
Q81326073VEGF receptor inhibition slows the progression of polycystic kidney disease
Q81019483VEGF significance in peritoneal recurrence from gastric cancer
Q80531924VEGF, VEGFRs expressions and activated STATs in ovarian epithelial carcinoma
Q36677407VEGF/VEGFR signalling as a target for inhibiting angiogenesis
Q39797640VEGFR-2 silencing by small interference RNA (siRNA) suppresses LPA-induced epithelial ovarian cancer (EOC) invasion
Q36621786Vascular endothelial growth factor (VEGF) expression is a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix
Q40706795Vascular endothelial growth factor (VEGF) is expressed by neoplastic Hodgkin-Reed-Sternberg cells in Hodgkin's disease
Q36292182Vascular endothelial growth factor (VEGF) mRNA isoform expression pattern is correlated with liver metastasis and poor prognosis in colon cancer
Q80565368Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinoma
Q73179856Vascular endothelial growth factor and its correlation with angiogenesis and p53 expression in prostate cancer
Q73585854Vascular endothelial growth factor and its receptors in normal human testicular tissue
Q52129432Vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression in the chick embryo area vasculosa.
Q37059490Vascular endothelial growth factor expression and inhibition in uveal melanoma cell lines
Q36414088Vascular endothelial growth factor expression correlates with serum CA125 and represents a useful tool in prediction of refractoriness to platinum-based chemotherapy and ascites formation in epithelial ovarian cancer
Q53359012Vascular endothelial growth factor expression in early stage ovarian carcinoma
Q42047538Vascular endothelial growth factor expression in ovarian serous carcinomas and its effect on tumor proliferation
Q38445978Vascular endothelial growth factor expression in serous ovarian carcinoma: relationship with topoisomerase II alpha and prognosis
Q36621192Vascular endothelial growth factor expression is independent of hypoxia in human malignant glioma spheroids and tumours
Q79085959Vascular endothelial growth factor in adnexal masses
Q35678769Vascular endothelial growth factor in females of reproductive age.
Q34107669Vascular endothelial growth factor in ovarian cancer
Q53328978Vascular endothelial growth factor in ovarian cyst fluid.
Q37357790Vascular endothelial growth factor is produced by peritoneal fluid macrophages in endometriosis and is regulated by ovarian steroids.
Q73047951Vascular endothelial growth factor measured in platelet poor plasma allows optimal separation between cancer patients and volunteers: a key to study an angiogenic marker in vivo?
Q28469224Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1
Q57005503Vascular endothelial growth factor messenger ribonucleic acid expression in human ovarian and endometrial cancer
Q40688027Vascular endothelial growth factor modulates the transendothelial migration of MDA-MB-231 breast cancer cells through regulation of brain microvascular endothelial cell permeability
Q34166351Vascular endothelial growth factor receptor-1 activation mediates epithelial to mesenchymal transition in hepatocellular carcinoma cells
Q24305184Vascular endothelial growth factor receptor-1 promotes migration and invasion in pancreatic carcinoma cell lines
Q28345678Vascular endothelial growth factor receptor-2-mediated mitogenesis is negatively regulated by vascular endothelial growth factor receptor-1 in tumor epithelial cells
Q35747351Vascular endothelial growth factor-165 overexpression stimulates angiogenesis and induces cyst formation and macrophage infiltration in human ovarian cancer xenografts
Q39664069Vascular endothelial growth factor-C promotes the growth and invasion of gallbladder cancer via an autocrine mechanism
Q41078547Vascular endothelial growth factor: environmental controls and effects in angiogenesis.
Q41221212Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas
Q41510549Visualization of tumor angiogenesis using MR imaging contrast agent Gd-DTPA-anti-VEGF receptor 2 antibody conjugate in a mouse tumor model
Q35753158What is the role of vascular endothelial growth factor-related molecules in tumor angiogenesis?
Q40967208Wide spectrum of antitumor activity of a neutralizing monoclonal antibody to human vascular endothelial growth factor

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