Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study

scientific article published on 01 July 2011

Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YGYNO.2011.06.019
P698PubMed publication ID21723597

P50authorCezary SzczylikQ9188497
Lubomir BodnarQ87887128
P2093author name stringMaria Górnas
P2860cites workPhase II clinical trial of sorafenib in metastatic medullary thyroid cancerQ27851560
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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesisQ29617585
Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluidQ29617640
Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trialQ30429122
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Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancerQ36623268
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Sorafenib efficacy in ovarian clear cell carcinoma revealed by transcriptome profiling.Q39637482
The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitorsQ40182316
Autocrine activation of PDGFRalpha promotes the progression of ovarian cancer.Q40343201
A front-line window of opportunity phase 2 study of sorafenib in patients with advanced nonsmall cell lung cancer: North Central Cancer Treatment Group Study N0326.Q42759889
Expression of vascular endothelial growth factor and its receptors flt and KDR in ovarian carcinoma.Q42805124
Sorafenib in Combination With Gemcitabine in Recurrent Epithelial Ovarian Cancer: A Study of the Princess Margaret Hospital Phase II ConsortiumQ42905241
Salvage therapy with topotecan in heavily pretreated ovarian cancer patientsQ46228021
Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome?Q46904135
Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinoma.Q52581305
Vascular endothelial growth factor expression in early stage ovarian carcinomaQ53359012
Randomized phase III trial of gemcitabine compared with pegylated liposomal doxorubicin in patients with platinum-resistant ovarian cancer.Q53965542
Sample Size Estimation: How Many Individuals Should Be Studied?Q73356424
Vascular endothelial growth factor C and vascular endothelial growth factor receptor 2 are related closely to the prognosis of patients with ovarian carcinomaQ80565368
P433issue1
P921main subjectovarian cancerQ172341
P304page(s)33-36
P577publication date2011-07-01
P1433published inGynecologic OncologyQ5625182
P1476titleSorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II study
P478volume123

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cites work (P2860)
Q52628568A phase II trial of Sunitinib malate in recurrent and refractory ovarian, fallopian tube and peritoneal carcinoma.
Q51065459A randomized phase II trial of maintenance therapy with Sorafenib in front-line ovarian carcinoma.
Q35205410Anti-vascular therapies in ovarian cancer: moving beyond anti-VEGF approaches.
Q38813996Clinical outcome of treatment with serine-threonine kinase inhibitors in recurrent epithelial ovarian cancer: a systematic review of literature.
Q98386430Clinical outcomes and safety of apatinib monotherapy in the treatment of patients with advanced epithelial ovarian carcinoma who progressed after standard regimens and the analysis of the VEGFR2 polymorphism
Q38038489Clinical trials and future potential of targeted therapy for ovarian cancer
Q39710264Design and Reporting of Targeted Anticancer Preclinical Studies: A Meta-Analysis of Animal Studies Investigating Sorafenib Antitumor Efficacy
Q91789025Efficacy And Safety Of Apatinib Treatment In Platinum-Resistant Recurrent Epithelial Ovarian Cancer: A Real World Study
Q36270115Inefficiencies and Patient Burdens in the Development of the Targeted Cancer Drug Sorafenib: A Systematic Review
Q37185385Network analysis identifies an HSP90-central hub susceptible in ovarian cancer
Q35837949Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
Q48012324Phase II study of paclitaxel associated with lipid core nanoparticles (LDE) as third-line treatment of patients with epithelial ovarian carcinoma
Q90408668Preclinical assessment of the VEGFR inhibitor axitinib as a therapeutic agent for epithelial ovarian cancer
Q26751280Profile of bevacizumab in the treatment of platinum-resistant ovarian cancer: current perspectives
Q87424383Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer
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Q50345037The rise of genomic profiling in ovarian cancer
Q36910794Translational predictive biomarker analysis of the phase 1b sorafenib and bevacizumab study expansion cohort.
Q37610081Two cases of recurrent ovarian clear cell carcinoma treated with sorafenib

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