Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer

scientific article published on 12 March 2014

Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10637-014-0078-5
P698PubMed publication ID24619298

P50authorPingfu FuQ63677685
P2093author name stringJohn J Wright
Robert M Wenham
Afshin Dowlati
Nancy Fusco
Vivian E von Gruenigen
Steven Waggoner
Heidi Frasure
Susan Eaton
Anita Schwandt
P2860cites workMutations of the BRAF gene in human cancerQ27860760
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of CanadaQ27860904
Sorafenib in advanced hepatocellular carcinomaQ27861075
Sorafenib in advanced clear-cell renal-cell carcinomaQ28282767
Activity of sorafenib in recurrent ovarian cancer and primary peritoneal carcinomatosis: a gynecologic oncology group trialQ30429122
Sorafenib in combination with weekly topotecan in recurrent ovarian cancer, a phase I/II study of the Hoosier Oncology Group.Q33397386
Risk of serious toxicity in 1181 patients treated in phase I clinical trials of predominantly targeted anticancer drugs: the M. D. Anderson Cancer Center experienceQ33399986
Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicityQ33658626
A phase 3 trial of bevacizumab in ovarian cancerQ34030022
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer.Q36610990
Association of c-Raf expression with survival and its targeting with antisense oligonucleotides in ovarian cancerQ36623268
Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trialQ36680034
Cutaneous squamous cell carcinoma and inflammation of actinic keratoses associated with sorafenibQ36781452
OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancerQ36822179
Sorafenib in Combination With Gemcitabine in Recurrent Epithelial Ovarian Cancer: A Study of the Princess Margaret Hospital Phase II ConsortiumQ42905241
Incorporation of bevacizumab in the primary treatment of ovarian cancerQ44579933
Keratoacanthomas and squamous cell carcinomas in patients receiving sorafenib.Q45930106
Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study.Q46029883
Multiple keratoacanthomas arising in the setting of sorafenib therapy: novel chemoprophylaxis with bexaroteneQ46200338
Optimal two-stage designs for phase II clinical trialsQ46412217
Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnibQ46535532
Point mutation of the ras oncogene in human ovarian cancerQ70477544
Second-line therapy with paclitaxel and carboplatin for recurrent disease following first-line therapy with paclitaxel and platinum in ovarian or peritoneal carcinomaQ74463809
Skin tumors induced by sorafenib; paradoxic RAS-RAF pathway activation and oncogenic mutations of HRAS, TP53, and TGFBR1Q82567338
Sorafenib as a third line therapy in patients with epithelial ovarian cancer or primary peritoneal cancer: a phase II studyQ84491268
P433issue4
P921main subjectuterine tubeQ1233836
fallopian tube cancerQ4818922
fallopian tube carcinomaQ18554948
phase II clinical trialQ42824440
P304page(s)729-738
P577publication date2014-03-12
P1433published inInvestigational New DrugsQ2312231
P1476titleRandomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer
P478volume32

Reverse relations

cites work (P2860)
Q26779120Beyond Bevacizumab: An Outlook to New Anti-Angiogenics for the Treatment of Ovarian Cancer
Q38813996Clinical outcome of treatment with serine-threonine kinase inhibitors in recurrent epithelial ovarian cancer: a systematic review of literature.
Q36270115Inefficiencies and Patient Burdens in the Development of the Targeted Cancer Drug Sorafenib: A Systematic Review
Q47096976Systemic therapy for recurrent epithelial ovarian cancer: a clinical practice guideline
Q98164379Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence
Q50345037The rise of genomic profiling in ovarian cancer
Q55385227Tumor angiogenesis and anti-angiogenic gene therapy for cancer.

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