Abstract is: Katherine J. Franz (born 1972) is the Chair of the Department Chemistry at Duke University. She studies metal ion coordination in biological systems and looks to use the insight to manage species such as copper and iron. Franz was awarded the American Chemical Society Award for Encouraging Women into Careers in the Chemical Sciences.
human | Q5 |
P2671 | Google Knowledge Graph ID | /g/11hds0t7v2 |
P496 | ORCID iD | 0000-0002-9015-0998 |
P3829 | Publons author ID | 1551980 |
P1053 | ResearcherID | D-3501-2011 |
P1153 | Scopus author ID | 7005385472 |
P166 | award received | ACS Award for Encouraging Women into Careers in the Chemical Sciences | Q4650822 |
P69 | educated at | Massachusetts Institute of Technology | Q49108 |
Wellesley College | Q49205 | ||
P108 | employer | Duke University | Q168751 |
P734 | family name | Franz | Q2696104 |
Franz | Q2696104 | ||
Franz | Q2696104 | ||
P735 | given name | Katherine | Q108631 |
Katherine | Q108631 | ||
P106 | occupation | chemist | Q593644 |
P21 | sex or gender | female | Q6581072 |
Q35696303 | A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence |
Q46858243 | A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination |
Q62083471 | A Pro-Chelator Triggered by Hydrogen Peroxide Inhibits Iron-Promoted Hydroxyl Radical Formation |
Q36630665 | A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding |
Q62083465 | A comparison of methionine, histidine and cysteine in copper(i)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments |
Q36167142 | A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress |
Q46420793 | A photolabile ligand for light-activated release of caged copper |
Q31137213 | A powerful combinatorial screen to identify high-affinity terbium(III)-binding peptides |
Q33815126 | A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation |
Q33824308 | A prochelator activated by hydrogen peroxide prevents metal-induced amyloid Beta aggregation |
Q53671360 | A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity. |
Q34132325 | A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting |
Q67185187 | Aminotroponiminates as Ligands for Potential Metal-Based Nitric Oxide Sensors |
Q62083464 | Application of inorganic chemistry for non-cancer therapeutics |
Q37387617 | Application of metal coordination chemistry to explore and manipulate cell biology |
Q102204656 | Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo-β-Lactamase NDM-1 |
Q38741123 | Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury |
Q62083462 | Characterization of a Photoswitching Chelator with Light-Modulated Geometric, Electronic, and Metal-Binding Properties |
Q36957543 | Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. |
Q48932251 | Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans. |
Q36791445 | Clawing back: broadening the notion of metal chelators in medicine |
Q34568034 | Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. |
Q37972055 | Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function |
Q42820956 | Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1. |
Q52647045 | Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria. |
Q67185181 | Copper shares a piece of the π |
Q38947366 | Copper signaling axis as a target for prostate cancer therapeutics |
Q90175020 | Correction to Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria |
Q46829936 | Counterions influence reactivity of metal ions with cysteinyldopa model compounds |
Q42925524 | Development of next-generation photolabile copper cages with improved copper binding properties |
Q43157898 | Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand |
Q93080390 | Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit |
Q34219760 | Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection |
Q34516910 | Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid |
Q96433249 | Fluconazole analogues with metal-binding motifs impact metal-dependent processes and demonstrate antifungal activity in Candida albicans |
Q62083469 | Introduction to “Cellular Metal Homeostasis and Trafficking” |
Q93126833 | Introduction: Metals in Medicine |
Q39932670 | Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide. |
Q37829985 | Keys for unlocking photolabile metal-containing cages |
Q35071893 | LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH) |
Q67185185 | Lanthanide-Binding Tags as Versatile Protein Coexpression Probes |
Q67185143 | Leveraging γ-Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells |
Q62083463 | Light uncages a copper complex to induce nonapoptotic cell death |
Q115652066 | Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli |
Q67185188 | Metal-Based NO Sensing by Selective Ligand Dissociation |
Q50147715 | Metal-binding hydrazone photoswitches for visible light reactivity and variable relaxation kinetics. |
Q43076637 | Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I). |
Q33813567 | Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease |
Q40641754 | Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1. |
Q35636795 | Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1. |
Q46907970 | Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress |
Q67185145 | Modifying aroylhydrazone prochelators for hydrolytic stability and improved cytoprotection against oxidative stress |
Q36391328 | Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe |
Q67185189 | Nitrosyl Transfer from Manganese to Iron in Tropocoronand Complexes |
Q42806086 | Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains |
Q35587484 | Pharmacological activity of metal binding agents that alter copper bioavailability |
Q46583981 | Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding |
Q62083470 | Phosphorylation-dependent metal binding by α-synuclein peptide fragments |
Q49084250 | Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA. |
Q36630737 | Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols |
Q36188483 | Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation |
Q33943982 | Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress |
Q58062307 | Protein Alignment by a Coexpressed Lanthanide-Binding Tag for the Measurement of Residual Dipolar Couplings |
Q104284997 | Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli |
Q48004595 | Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans |
Q43285401 | Stimulus-Responsive Prochelators for Manipulating Cellular Metals |
Q63296601 | Structural Origin of the High Affinity of a Chemically Evolved Lanthanide-Binding Peptide |
Q62083473 | Synthesis and Characterization of Copper(II) Complexes of Cysteinyldopa and Benzothiazine Model Ligands Related to Pheomelanin |
Q53707141 | The highways and byways of bioinorganic chemistry. |
Q46332165 | The hydrolytic susceptibility of prochelator BSIH in aqueous solutions |
Q34070368 | Toward the detection of cellular copper(II) by a light-activated fluorescence increase |
Q33805704 | Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress |
Katherine Franz | wikipedia |
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