Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide

scientific article published on November 5, 2010

Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BBRC.2010.10.137
P953full work available at URLhttps://api.elsevier.com/content/article/PII:S0006291X10020413?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006291X10020413?httpAccept=text/plain
P698PubMed publication ID21056550

P50authorLei JiangQ92616685
P2093author name stringJianbo Wu
Chong-Yun Xing
Kang Yu
Lihui Yin
Shen-meng Gao
Chiqi Chen
Yanxia Tan
Aifang Ye
P2860cites workmiR-15 and miR-16 induce apoptosis by targeting BCL2Q24536069
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
MiR-15a and miR-16-1 cluster functions in human leukemiaQ24647555
Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphomaQ24655119
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAsQ27861053
The enigma of arsenic carcinogenesis: role of metabolismQ28199536
miR-15a and miR-16-1 in cancer: discovery, function and future perspectivesQ28247489
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cellsQ28278471
The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activitiesQ28297958
A systems biology understanding of the synergistic effects of arsenic sulfide and Imatinib in BCR/ABL-associated leukemiaQ28387697
miRNA-21 regulates arsenic-induced anti-leukemia activity in myelogenous cell linesQ33530333
Regulation of cell death by the Abl tyrosine kinaseQ34103653
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxideQ34478428
BCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instabilityQ35022527
Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.Q35561038
The biology of CML blast crisisQ35675089
MicroRNAs and haematology: small molecules, big functionQ36835898
MicroRNAs in carcinogenesisQ37000285
MicroRNA: An emerging therapeutic target and intervention toolQ37135817
MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.Q38305314
Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosisQ38346521
Correcting miR-15a/16 genetic defect in New Zealand Black mouse model of CLL enhances drug sensitivityQ39805065
The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.Q39877545
MicroRNAs modulate the chemosensitivity of tumor cellsQ40026480
Nanomolar concentration of NSC606985, a camptothecin analog, induces leukemic-cell apoptosis through protein kinase Cdelta-dependent mechanisms.Q40465461
Combined effects of As4S4 and imatinib on chronic myeloid leukemia cells and BCR-ABL oncoproteinQ40520596
MicroRNAs and cancer: short RNAs go a long way.Q41906288
Synergistic mitosis-arresting effects of arsenic trioxide and paclitaxel on human malignant lymphocytesQ43271217
Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cellsQ43614308
Current therapy concepts in chronic myeloid leukemia. Study IV of the German CML Study GroupQ44276252
Down-regulation of stathmin is required for TGF-beta inducible early gene 1 induced growth inhibition of pancreatic cancer cellsQ46310536
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)203-208
P577publication date2010-11-05
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleSynergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxide
P478volume403

Reverse relations

cites work (P2860)
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Q35632171miR-15a and miR-16-1 inhibit the proliferation of leukemic cells by down-regulating WT1 protein level
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