Arsenic-Induced Carcinogenesis: The Impact of miRNA Dysregulation

scientific article published on 01 October 2018

Arsenic-Induced Carcinogenesis: The Impact of miRNA Dysregulation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/TOXSCI/KFY128
P932PMC publication ID6154275
P698PubMed publication ID29846715

P50authorJ C StatesQ69996897
P2093author name stringAna P Ferragut Cardoso
Laila Al-Eryani
P2860cites workMost mammalian mRNAs are conserved targets of microRNAsQ24655061
Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin: a dose-response studyQ24811866
Molecular mechanisms of epithelial-mesenchymal transitionQ27013743
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Role of reactive oxygen species in arsenic-induced transformation of human lung bronchial epithelial (BEAS-2B) cellsQ28385304
Cell lines: Valuable tools or useless artifactsQ39354412
Cyclooxygenase-2 expression is up-regulated by 2-aminobiphenyl in a ROS and MAPK-dependent signaling pathway in a bladder cancer cell lineQ39404382
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MicroRNA-181a modulates gene expression of zinc finger family members by directly targeting their coding regionsQ39686536
MicroRNA: Biogenesis, Function and Role in CancerQ42004179
Synergistic apoptosis induction in leukemic cells by miR-15a/16-1 and arsenic trioxideQ42833356
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Estimating the High-Arsenic Domestic-Well Population in the Conterminous United StatesQ45070353
Mouse skin tumor promotion by sodium arsenate is associated with enhanced PCNA expressionQ46487303
Vitamin E and organoselenium prevent the cocarcinogenic activity of arsenite with solar UVR in mouse skinQ46598627
Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in The TP53 Axis and Carcinogenesis Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic.Q47214159
MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cellsQ47249637
MicroRNA‑141 inhibits epithelial‑mesenchymal transition, and ovarian cancer cell migration and invasionQ47811207
The putative tumor suppressor, miR-199a, regulated by Snail, modulates clear cell renal cell carcinoma aggressiveness by repressing ROCK1.Q49263735
MicroRNA responses to cellular stress.Q52001739
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.Q52582850
Arsenic, metals, fibres, and dusts.Q53261539
Blockade of p53 by HIF-2α, but not HIF-1α, is involved in arsenite-induced malignant transformation of human bronchial epithelial cells.Q53272390
The role of MicroRNAs in human cancerQ89700410
Arsenic-Associated Changes to the Epigenome: What Are the Functional Consequences?Q28386272
Arsenic responsive microRNAs in vivo and their potential involvement in arsenic-induced oxidative stressQ28389940
Inorganic Arsenic-induced cellular transformation is coupled with genome wide changes in chromatin structure, transcriptome and splicing patternsQ28390396
RETRACTED ARTICLE: Oncogenic transformation of human lung bronchial epithelial cells induced by arsenic involves ROS-dependent activation of STAT3-miR-21-PDCD4 mechanismQ28394712
Effects of arsenic exposure on DNA methylation and epigenetic gene regulationQ28395938
Chronic arsenic exposure and angiogenesis in human bronchial epithelial cells via the ROS/miR-199a-5p/HIF-1α/COX-2 pathwayQ28397396
microRNA functionsQ29547393
MicroRNAs: tools for cancer diagnosticsQ33575602
Negative regulation of tumor suppressor p53 by microRNA miR-504Q33979178
Arsenite is a cocarcinogen with solar ultraviolet radiation for mouse skin: an animal model for arsenic carcinogenesis.Q34093044
An Emerging Role for Epigenetic Dysregulation in Arsenic Toxicity and CarcinogenesisQ34478447
Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.Q35164353
MicroRNA (miRNA) in cancerQ35583538
Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylationQ36440499
Arsenic contamination in groundwater: a global perspective with emphasis on the Asian scenario.Q36695114
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Arsenic-exposed Keratinocytes Exhibit Differential microRNAs Expression Profile; Potential Implication of miR-21, miR-200a and miR-141 in Melanoma PathwayQ36762980
Functional integration of microRNAs into oncogenic and tumor suppressor pathwaysQ37125039
Induction of cytoplasmic accumulation of p53: a mechanism for low levels of arsenic exposure to predispose cells for malignant transformation.Q37281055
Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteinsQ37721696
Identification and consequences of miRNA-target interactions--beyond repression of gene expressionQ38229290
MicroRNAs in cancer: biomarkers, functions and therapyQ38229952
Anti-miR-21 oligonucleotide sensitizes leukemic K562 cells to arsenic trioxide by inducing apoptosisQ38346521
Disruption of Mitotic Progression by Arsenic.Q38386478
MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells.Q38688222
Increased microRNA 21 expression contributes to arsenic induced skin lesions, skin cancers and respiratory distress in chronically exposed individualsQ38722254
The role of microRNAs in metal carcinogen-induced cell malignant transformation and tumorigenesisQ38745324
MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours.Q38768383
MicroRNA-21 activation of ERK signaling via PTEN is involved in arsenite-induced autophagy in human hepatic L-02 cellsQ38776012
Census and evaluation of p53 target genes.Q38911126
MicroRNA-21, up-regulated by arsenite, directs the epithelial-mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4.Q38935870
The acquisition of cancer stem cell-like properties and neoplastic transformation of human keratinocytes induced by arsenite involves epigenetic silencing of let-7c via Ras/NF-κB.Q39007522
Arsenite evokes IL-6 secretion, autocrine regulation of STAT3 signaling, and miR-21 expression, processes involved in the EMT and malignant transformation of human bronchial epithelial cellsQ39100333
MicroRNA-191, an estrogen-responsive microRNA, functions as an oncogenic regulator in human breast cancerQ39173393
P433issue2
P407language of work or nameEnglishQ1860
P921main subjecttoxicologyQ7218
carcinogenesisQ1637543
P304page(s)284-290
P577publication date2018-10-01
P1433published inToxicological SciencesQ2446966
P1476titleArsenic-Induced Carcinogenesis: The Impact of miRNA Dysregulation
P478volume165

Reverse relations

cites work (P2860)
Q64099547Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS
Q95276151MicroRNAs and Xenobiotic Toxicity: An Overview

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