Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity

scientific article published on 3 June 2011

Unsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.243485
P932PMC publication ID3143652
P698PubMed publication ID21642425

P50authorSucharit BhakdiQ1473437
Gerald GimplQ61793598
Karina ReissQ90781672
Matthias HusmannQ100292079
P2093author name stringIsabell Cornelsen
P2860cites workG-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent proteinQ45185003
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beta-Amyloid peptide decreases membrane fluidity.Q52017631
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Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesionQ74351422
An essential role for ectodomain shedding in mammalian developmentQ77544828
ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitisQ80503595
The shedding activity of ADAM17 is sequestered in lipid raftsQ24305222
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)Q24306455
Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin sheddingQ24307862
ADAM17 deficiency by mature neutrophils has differential effects on L-selectin sheddingQ24685839
The ADAM metalloproteinasesQ28292696
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell lineQ29547520
Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injuryQ30156106
Pore-forming Staphylococcus aureus alpha-toxin triggers epidermal growth factor receptor-dependent proliferationQ30159638
Dynamics of putative raft-associated proteins at the cell surfaceQ33203351
Fourier transform infrared imaging showing reduced unsaturated lipid content in the hippocampus of a mouse model of Alzheimer's diseaseQ33764514
Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidityQ33784636
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.Q33878896
L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowthQ34097273
Hyperfluidization-coupled membrane microdomain reorganization is linked to activation of the heat shock response in a murine melanoma cell lineQ35808829
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.Q35897595
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.Q36074351
On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moietyQ36365606
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alphaQ37127274
Part-time alpha-secretases: the functional biology of ADAM 9, 10 and 17.Q37130668
Regulation of the proteolytic disintegrin metalloproteinases, the 'Sheddases'.Q37289019
The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer.Q37308499
The ADAMs: signalling scissors in the tumour microenvironmentQ37324256
The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functionsQ37339450
PUFA for prevention and treatment of dementia?Q37664786
Human oxytocin receptors in cholesterol-rich vs. cholesterol-poor microdomains of the plasma membraneQ40883416
Role of fatty acids in the pathogenesis of insulin resistance and NIDDM.Q41275648
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin.Q41840639
Isolation and characterization of a complement-activating lipid extracted from human atherosclerotic lesionsQ41954726
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic siteQ42382724
A disintegrin and metalloprotease 10 is a novel mediator of vascular endothelial growth factor-induced endothelial cell function in angiogenesis and is associated with atherosclerosis.Q42674129
Enzymatically modified nonoxidized low-density lipoprotein induces interleukin-8 in human endothelial cells: role of free fatty acidsQ44213383
Possible protective role for C-reactive protein in atherogenesis: complement activation by modified lipoproteins halts before detrimental terminal sequenceQ44810016
A cellular metalloproteinase activates Vibrio cholerae pro-cytolysinQ44832222
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectfatty acidQ61476
cell adhesionQ187640
P304page(s)26931-26942
P577publication date2011-06-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleUnsaturated fatty acids drive disintegrin and metalloproteinase (ADAM)-dependent cell adhesion, proliferation, and migration by modulating membrane fluidity
P478volume286

Reverse relations

cites work (P2860)
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Q64262926Elevated serum HER-2 predicts poor prognosis in breast cancer and is correlated to ADAM10 expression
Q36836028Enzymatically Modified Low-Density Lipoprotein Is Present in All Stages of Aortic Valve Sclerosis: Implications for Pathogenesis of the Disease
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