Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase

scientific article published on August 4, 2010

Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/KI.2010.265
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/ki.2010.265
P953full work available at URLhttp://www.kidney-international.org/article/S0085253815546619/pdf
P698PubMed publication ID20686447

P50authorToyoshi InoguchiQ90437954
P2093author name stringJing Zheng
Ryoichi Takayanagi
Yasutaka Maeda
Kunihisa Kobayashi
Shuji Sasaki
Masakazu Fujii
P2860cites workIdentification of renox, an NAD(P)H oxidase in kidneyQ22254385
Bilirubin is an antioxidant of possible physiological importanceQ28288206
Mechanisms underlying endothelial dysfunction in diabetes mellitusQ31829307
Melatonin decreases neurovascular oxidative/nitrosative damage and protects against early increases in the blood-brain barrier permeability after transient focal cerebral ischemia in miceQ33252362
A novel superoxide-producing NAD(P)H oxidase in kidneyQ33921569
Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in ratsQ33989668
Protein kinase C-dependent increase in reactive oxygen species (ROS) production in vascular tissues of diabetes: role of vascular NAD(P)H oxidaseQ34216090
Vascular NAD(P)H oxidases: specific features, expression, and regulationQ35175526
Heme oxygenase and the cardiovascular-renal systemQ36144605
Heme oxygenase and atherosclerosisQ36195421
NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndromeQ36198742
Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004.Q37001252
Protein glycation and oxidative stress in diabetes mellitus and ageingQ37192112
Role of oxidative stress in development of complications in diabetesQ37681089
Induction of haem oxygenase as a defence against oxidative stressQ37928482
Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesityQ38340354
Free radicals and diabetesQ39578509
Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systemsQ41069909
A new method for large scale isolation of kidney glomeruli from miceQ42047954
Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetesQ43867580
Accumulation of 8-hydroxy-2'-deoxyguanosine and mitochondrial DNA deletion in kidney of diabetic ratsQ43972574
Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatmentQ44589042
Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic NephropathyQ44599816
Relationship of serum bilirubin concentrations to kidney function and albuminuria in the United States adult population. Findings from the National Health and Nutrition Examination Survey 2001-2006.Q45918859
Statin attenuates high glucose-induced and diabetes-induced oxidative stress in vitro and in vivo evaluated by electron spin resonance measurementQ46617952
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidneyQ46681131
Higher serum bilirubin is associated with decreased risk for early familial coronary artery disease.Q51034508
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cellsQ63365807
Bilirubin inhibits the activation of superoxide-producing NADPH oxidase in a neutrophil cell-free systemQ67913939
Serum bilirubin and risk of ischemic heart disease in middle-aged British menQ71808154
DNA damage in the kidneys of diabetic rats exhibiting microalbuminuriaQ71999728
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cellsQ73190327
Pitavastatin ameliorates albuminuria and renal mesangial expansion by downregulating NOX4 in db/db miceQ80477528
Relationship between Gilbert syndrome and prevalence of vascular complications in patients with diabetesQ81352389
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectdiabetic nephropathyQ1129105
P304page(s)905-919
P577publication date2010-08-04
P1433published inKidney InternationalQ6404823
P1476titleBilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase
P478volume78

Reverse relations

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