| scholarly article | Q13442814 |
| editorial | Q871232 |
| P50 | author | Jeffrey A Bluestone | Q87186905 |
| P2093 | author name string | Bernhard O Boehm | |
| P2860 | cites work | CD28/B7 costimulation: a review | Q22003996 |
| Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation | Q24675931 | ||
| A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells | Q28137753 | ||
| The immunological synapse: a molecular machine controlling T cell activation | Q28139151 | ||
| B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes | Q28143530 | ||
| Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease | Q28201947 | ||
| PD-L2 is a second ligand for PD-1 and inhibits T cell activation | Q28202471 | ||
| Genetics of type 1 diabetes mellitus | Q28215982 | ||
| Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A | Q28216798 | ||
| Molecular basis of T cell inactivation by CTLA-4 | Q28291723 | ||
| Toll-like receptors in innate immunity | Q28297257 | ||
| An autoimmune disease-associated CTLA-4 splice variant lacking the B7 binding domain signals negatively in T cells | Q28610420 | ||
| The effect of infections on susceptibility to autoimmune and allergic diseases | Q29618525 | ||
| Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4 | Q29619280 | ||
| B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha | Q30807749 | ||
| Low dose streptozotocin-induced diabetes in rat insulin promoter-mCD80-transgenic mice is T cell autoantigen-specific and CD28 dependent | Q31839111 | ||
| Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes | Q33197128 | ||
| T cell co-stimulatory molecules other than CD28. | Q33664723 | ||
| Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation | Q34178136 | ||
| Towards a network theory of the immune system. | Q34202813 | ||
| Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses | Q34503361 | ||
| Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. | Q34509694 | ||
| The B7-CD28 superfamily | Q34575331 | ||
| Structural mechanisms of costimulation | Q34614732 | ||
| Genetic control of autoimmunity in Type I diabetes and associated disorders | Q34728213 | ||
| Control of autoimmune diseases by the B7-CD28 family molecules. | Q35644278 | ||
| The roles of the new negative T cell costimulatory pathways in regulating autoimmunity | Q35772868 | ||
| Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse | Q36364541 | ||
| B7-1 or B7-2 is required to produce the lymphoproliferative phenotype in mice lacking cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) | Q36367912 | ||
| Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen | Q36402656 | ||
| B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28. | Q36851775 | ||
| Role of the CD28 receptor in T-cell activation | Q37881494 | ||
| The third signal in T cell-mediated autoimmune disease? | Q38339806 | ||
| Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. | Q40051110 | ||
| The role of CD40 in the regulation of humoral and cell-mediated immunity | Q40393797 | ||
| Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse. | Q40501687 | ||
| Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays | Q40797897 | ||
| CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease | Q40841269 | ||
| The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A. | Q40850973 | ||
| Regulation of T cell activation by CD28 and CTLA4. | Q41204378 | ||
| Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1. | Q41417560 | ||
| CTLA-4-Ig regulates tryptophan catabolism in vivo. | Q44170968 | ||
| Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease | Q44285977 | ||
| Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells. | Q44835546 | ||
| CTLA-4 regulates the requirement for cytokine-induced signals in T(H)2 lineage commitment | Q46457840 | ||
| Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function | Q46468450 | ||
| T-cell-antigen recognition and the immunological synapse | Q46522042 | ||
| Expression of the B7.1 costimulatory molecule on pancreatic beta cells abrogates the requirement for CD4 T cells in the development of type 1 diabetes | Q47232005 | ||
| Beta cell-specific CD80 (B7-1) expression disrupts tissue protection from autoantigen-specific CTL-mediated diabetes. | Q53939811 | ||
| Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33 | Q56906182 | ||
| CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes | Q56908828 | ||
| A search for type 1 diabetes susceptibility genes in families from the United Kingdom | Q64134325 | ||
| CD28 costimulation promotes the production of Th2 cytokines | Q71968314 | ||
| Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells | Q73112924 | ||
| IL-1 enhances T cell-dependent antibody production through induction of CD40 ligand and OX40 on T cells | Q74064935 | ||
| Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice | Q78431873 | ||
| Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig | Q79290408 | ||
| P433 | issue | 4 | |
| P921 | main subject | type-1 diabetes | Q124407 |
| P304 | page(s) | 156-164 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | The review of diabetic studies : RDS | Q26853988 |
| P1476 | title | Differential roles of costimulatory signaling pathways in type 1 diabetes mellitus | |
| P478 | volume | 1 |
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