Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation

scientific article published on April 1996

Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ3150041
P932PMC publication ID1217194
P698PubMed publication ID8670130
P5875ResearchGate publication ID14531496

P2093author name stringMartin H
Aitken A
Wheeler-Jones CP
Learmonth MP
P2860cites workActivation of Raf-1 by 14-3-3 proteinsQ24324360
Characterization of 14-3-3 proteins in adrenal chromaffin cells and demonstration of isoform-specific phospholipid bindingQ24528262
Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathwaysQ27729753
Association of a phospholipase A2 (14-3-3 protein) with the platelet glycoprotein Ib-IX complexQ28245163
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteinsQ28293607
Protein kinase recognition sequence motifsQ29620224
Studies and perspectives of protein kinase C.Q34162282
14-3-3: modulators of signaling proteins?Q34324416
14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteinsQ35624026
Molecular mechanisms of platelet activationQ38264192
Expression and structural analysis of 14-3-3 proteins.Q38299549
The use of inhibitors of protein kinases and protein phosphatases to investigate the role of protein phosphorylation in platelet activation.Q40765743
Association of the protein kinases c-Bcr and Bcr-Abl with proteins of the 14-3-3 familyQ41436352
Effect of alpha-protein kinase C neutralizing antibodies and the pseudosubstrate peptide on phosphorylation, migration, and growth of REF52 cells.Q41561116
Identification and functional characterization of protein kinase C isozymes in platelets and HEL cellsQ41624365
A pseudosubstrate peptide inhibits protein kinase C-mediated phosphorylation in permeabilized Rat-1 cellsQ41744163
Mastoparan promotes exocytosis and increases intracellular cyclic AMP in human platelets. Evidence for the existence of a Ge-like mechanism of secretionQ41813400
Effect of phorbol ester treatment on receptor-mediated versus G-protein-activator-mediated responses in platelets. Evidence for a two-site action of phorbol ester at the level of G-protein functionQ41868334
Effect of tumour-promoting phorbol ester, thrombin and vasopressin on translocation of three distinct protein kinase C isoforms in human platelets and regulation by calciumQ42161374
Identification of a key domain in annexin and 14-3-3 proteins that stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cellsQ42620975
Mechanism of inhibition of protein kinase C by 14-3-3 isoforms. 14-3-3 isoforms do not have phospholipase A2 activityQ42752618
Receptor- and phorbol-ester-mediated redistribution of protein kinase C in human platelets. Evidence that aggregation promotes degradation of protein kinase C.Q42804358
p42 mitogen-activated protein kinase and p90 ribosomal S6 kinase are selectively phosphorylated and activated during thrombin-induced platelet activation and aggregationQ43181448
Cloning and expression of a human 14-3-3 protein mediating phospholipolysis. Identification of an arachidonoyl-enzyme intermediate during catalysis.Q43798751
Multiple isoforms of a protein kinase C inhibitor (KCIP-1/14-3-3) from sheep brain. Amino acid sequence of phosphorylated formsQ44926293
Kinase and neurotransmittersQ45016157
Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzymeQ45971419
Purification of 14-3-3 protein and analysis of isoforms in chicken brain.Q48087654
Protein kinase C inhibitor proteins. Purification from sheep brain and sequence similarity to lipocortins and 14-3-3 proteinQ48259445
Exo1 and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cellsQ48525974
Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cellsQ52779025
Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein.Q54649952
Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicityQ68149927
Regulation of platelet protein kinase C by oleic acid. Kinetic analysis of allosteric regulation and effects on autophosphorylation, phorbol ester binding, and susceptibility to inhibitionQ68354530
Protein kinase C isotypes and signal-transduction in human neutrophils: selective substrate specificity of calcium-dependent beta-PKC and novel calcium-independent nPKCQ70656409
Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase CQ70920291
14-3-3 proteins on the MAPQ72139467
14-3-3 alpha and delta are the phosphorylated forms of raf-activating 14-3-3 beta and zeta. In vivo stoichiometric phosphorylation in brain at a Ser-Pro-Glu-Lys MOTIFQ72631513
Subcellular localisation of 14-3-3 isoforms in rat brain using specific antibodiesQ72815795
P407language of work or nameEnglishQ1860
P304page(s)41-47
P577publication date1996-04-01
P1433published inBiochemical JournalQ864221
P1476titleIdentification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation
P478volume315 ( Pt 1)

Reverse relations

cites work (P2860)
Q5233062214-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.
Q4448081614-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta
Q2731040614-3-3ζ interacts with stat3 and regulates its constitutive activation in multiple myeloma cells
Q34718342Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in platelets.
Q53763933Expression of 14-3-3 zeta and interaction with protein kinase C in the rat retina in early diabetes.
Q34997206Global analysis of the rat and human platelet proteome - the molecular blueprint for illustrating multi-functional platelets and cross-species function evolution.
Q45205636Human red blood cells contain antifibrogenic factors that stimulate MMP-1 expression in dermal fibroblasts
Q51778499Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets.
Q42927395Platelet apoptosis by cold‐induced glycoprotein Ibα clustering
Q40168622Proliferative effect of calcitonin gene-related peptide is induced by at least five proteins as identified by proteome profiling
Q28139665Protein kinase C mu is negatively regulated by 14-3-3 signal transduction proteins
Q33246067Proteomic analysis of differential protein expression in atherosclerosis
Q35881717The Effect of Oxytocin on Social and Non-Social Behaviour and Striatal Protein Expression in C57BL/6N Mice
Q33538365The regulation of neurotransmitter secretion by protein kinase C.
Q29547190The structural basis for 14-3-3:phosphopeptide binding specificity
Q28139698alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

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