The p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2.

scientific article published on 12 December 2012

The p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VIRUSRES.2012.12.005
P932PMC publication ID7114515
P698PubMed publication ID23246447
P5875ResearchGate publication ID233940204

P50authorJude Juventus AweyaQ37842960
P2093author name stringYee-Joo Tan
Seng Gee Lim
Tze Minn Mak
P2860cites workIdentification and characterization of CPP32/Mch2 homolog 1, a novel cysteine protease similar to CPP32Q24317687
Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene familyQ24324217
The natural history of hepatitis C virus (HCV) infectionQ27473116
The hepatitis C virus p7 protein forms an ion channel that is inhibited by long-alkyl-chain iminosugar derivativesQ27477454
Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious VirionsQ27480902
Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C terminiQ27485927
Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In VitroQ27488995
Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistenceQ27489673
Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-ComplementationQ27490303
NMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C VirusQ27663637
Production of infectious hepatitis C virus in tissue culture from a cloned viral genomeQ27860899
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1Q28282333
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complexQ28283294
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymeraseQ28302692
A drug screening method based on the autophagy pathway and studies of the mechanism of evodiamine against influenza A virusQ28482183
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin AQ28610837
Genetic diversity and evolution of hepatitis C virus--15 years onQ29547888
The Beclin 1 network regulates autophagy and apoptosisQ29616539
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, AmantadineQ29620670
Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.Q30491528
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosisQ33779488
Caspase inhibitors.Q33782509
A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assemblyQ33981285
Generation of a cell culture-adapted hepatitis C virus with longer half life at physiological temperatureQ33988533
Viroporins.Q34230206
Death by design: apoptosis, necrosis and autophagyQ34365753
Major DNA fragmentation is a late event in apoptosisQ34431596
Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomesQ35013357
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 proteinQ35097566
Cation channels, cell volume and the death of an erythrocyteQ35194861
Beclin-1 targeting for viral immune escapeQ35261527
Impact of the autophagy machinery on hepatitis C virus infectionQ35261712
Ion channels and membrane rafts in apoptosis.Q35741073
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL proteinQ35857154
Knockdown of autophagy enhances the innate immune response in hepatitis C virus-infected hepatocytesQ35910776
Beyond apoptosis: nonapoptotic cell death in physiology and disease.Q36290514
K+ channels in apoptosisQ36473830
Alternate functions of viral regulators of cell deathQ36495167
Caspase function in programmed cell deathQ36643566
Hepatitis C virus infection and apoptosisQ36935539
Targeting Beclin 1 for viral subversion of macroautophagy.Q37653910
Modulation of programmed cell death pathways by the hepatitis C virusQ37825167
Hepatitis C virus p7: molecular function and importance in hepatitis C virus life cycle and potential antiviral target.Q37860404
The crosstalk between autophagy and apoptosis: where does this lead?Q37982296
Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapyQ38615924
Dysfunction of autophagy participates in vacuole formation and cell death in cells replicating hepatitis C virusQ39458949
The Beclin 1 interactomeQ40011745
Viroporins from RNA viruses induce caspase-dependent apoptosisQ40062300
The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomesQ40250494
Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope proteinQ40310467
A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondriaQ40532455
Caspase-dependent apoptosis and -independent poly(ADP-ribose) polymerase cleavage induced by transforming growth factor beta1.Q40612084
Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7.Q40927226
Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell deathQ41717170
Inhibition of human caspases by peptide-based and macromolecular inhibitorsQ42538024
Expression of a full-length hepatitis C virus cDNA up-regulates the expression of CC chemokines MCP-1 and RANTES.Q43041449
Hepatitis C virus infection enhances TNFα-induced cell death via suppression of NF-κB.Q43418500
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C.Q45414305
Life and death partners: apoptosis, autophagy and the cross-talk between themQ46072576
The ion channel activity of the SARS-coronavirus 3a protein is linked to its pro-apoptotic function.Q47931510
Methods for monitoring autophagy using GFP-LC3 transgenic mice.Q50603642
Hepatitis C and liver transplantationQ59098576
P4510describes a project that usesImageJQ1659584
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectHepatitis C virusQ708693
influenza A virusQ834390
cell deathQ2383867
P304page(s)24-34
P577publication date2012-12-12
P1433published inVirus ResearchQ15749215
P1476titleThe p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2.
P478volume172

Reverse relations

cites work (P2860)
Q37547531Adenovirus death protein (ADP) is required for lytic infection of human lymphocytes.
Q34069393Autophagy in HCV infection: keeping fat and inflammation at bay
Q40084069Hepatitis C Virus-Induced Autophagy and Host Innate Immune Response
Q52716681Hepatitis C virus NS5A protein promotes the lysosomal degradation of hepatocyte nuclear factor 1α via chaperone-mediated autophagy.
Q36652533Hepatitis C virus and autophagy
Q40047300NS2A comprises a putative viroporin of Dengue virus 2.
Q38933203NS5B induces up-regulation of the BH3-only protein, BIK, essential for the hepatitis C virus RNA replication and viral release
Q40718894Porcine reproductive and respiratory syndrome virus envelope (E) protein interacts with mitochondrial proteins and induces apoptosis
Q36428473Recombinant Dengue virus protein NS2B alters membrane permeability in different membrane models
Q90383656Regulation of Autophagy in Cells Infected With Oncogenic Human Viruses and Its Impact on Cancer Development
Q41504905The Molecular Switch of Telomere Phages: High Binding Specificity of the PY54 Cro Lytic Repressor to a Single Operator Site
Q36442330The Non-structural Protein of Crimean-Congo Hemorrhagic Fever Virus Disrupts the Mitochondrial Membrane Potential and Induces Apoptosis
Q27026459The elusive function of the hepatitis C virus p7 protein
Q27000898Viral Membrane Channels: Role and Function in the Virus Life Cycle
Q111086228Viroporins: structure, function, and their role in the life cycle of SARS-CoV-2
Q24567565mTOR/p70S6K signaling distinguishes routine, maintenance-level autophagy from autophagic cell death during influenza A infection

Search more.