The Non-structural Protein of Crimean-Congo Hemorrhagic Fever Virus Disrupts the Mitochondrial Membrane Potential and Induces Apoptosis

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The Non-structural Protein of Crimean-Congo Hemorrhagic Fever Virus Disrupts the Mitochondrial Membrane Potential and Induces Apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.667436
P932PMC publication ID4705379
P698PubMed publication ID26574543

P50authorYee-Joo TanQ58208732
P2093author name stringAli Mirazimi
Helen Karlberg
Bhaskar Barnwal
P2860cites workNSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinaseQ39195523
Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSsQ39601913
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Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell deathQ39776458
Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injuryQ39946452
NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcriptionQ39960501
Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cellsQ40221530
Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosisQ40270295
Crimean-Congo haemorrhagic fever virus: sequence analysis of the small RNA segments from a collection of viruses world wideQ40535959
Caspases: key mediators of apoptosisQ41760384
NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machineryQ42218809
Inhibition of human caspases by peptide-based and macromolecular inhibitorsQ42538024
The p7 protein of the hepatitis C virus induces cell death differently from the influenza A virus viroporin M2.Q42987338
Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infectionQ45778467
Non-structural and nucleocapsid proteins of Punta Toro virus induce apoptosis of hepatocytes through both intrinsic and extrinsic pathways.Q54447288
Crimean-Congo hemorrhagic feverQ56505903
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2Q24670800
Regulation of apoptosis by viral gene productsQ24678703
Inhibition of Translation and Induction of Apoptosis by Bunyaviral Nonstructural Proteins Bearing Sequence Similarity to ReaperQ27481525
Crimean-Congo haemorrhagic feverQ27860350
Protein secondary structure prediction based on position-specific scoring matricesQ27860483
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1Q28282333
Crimean-Congo hemorrhagic fever: current and future prospects of vaccines and therapiesQ28306281
Viral control of mitochondrial apoptosisQ28472776
Crimean-Congo hemorrhagic fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversityQ29041244
Caspases: enemies withinQ29547315
Mitochondrial control of cell deathQ29617739
Role of actin filaments in targeting of Crimean Congo hemorrhagic fever virus nucleocapsid protein to perinuclear regions of mammalian cellsQ30233356
Vesicular stomatitis viruses expressing wild-type or mutant M proteins activate apoptosis through distinct pathwaysQ33707420
Caspase inhibitors.Q33782509
Efficient cDNA-based rescue of La Crosse bunyaviruses expressing or lacking the nonstructural protein NSs.Q33911860
Crimean-Congo hemorrhagic fever virus-infected hepatocytes induce ER-stress and apoptosis crosstalkQ34125207
Molecular biology of the BunyaviridaeQ34204009
Topology prediction for helical transmembrane proteins at 86% accuracyQ34400903
Induction of caspase activation and cleavage of the viral nucleocapsid protein in different cell types during Crimean-Congo hemorrhagic fever virus infectionQ34536774
Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesisQ34625091
The transient nature of Bunyamwera orthobunyavirus NSs protein expression: effects of increased stability of NSs protein on virus replicationQ34718537
Bunyamwera bunyavirus nonstructural protein NSs counteracts the induction of alpha/beta interferon.Q35000433
Viral modulators of cell death provide new links to old pathwaysQ35595916
Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL proteinQ35857154
The C-terminal region of Rift Valley fever virus NSm protein targets the protein to the mitochondrial outer membrane and exerts antiapoptotic functionQ36506825
A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activationQ36525307
GRIM-19 is essential for maintenance of mitochondrial membrane potentialQ36631152
Caspase function in programmed cell deathQ36643566
Identification of virus-coded nonstructural polypeptides in bunyavirus-infected cellsQ36938630
Crimean-Congo haemorrhagic fever replication interplays with regulation mechanisms of apoptosis.Q38931688
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectOrthonairovirus haemorrhagiaeQ1788951
P304page(s)582-592
P577publication date2015-11-16
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe Non-structural Protein of Crimean-Congo Hemorrhagic Fever Virus Disrupts the Mitochondrial Membrane Potential and Induces Apoptosis
P478volume291

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