Chronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint

scientific article published in November 2012

Chronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.JOCA.2012.10.014
P932PMC publication ID3556233
P698PubMed publication ID23123358
P5875ResearchGate publication ID232811978

P50authorMack Gardner-MorseQ42074615
P2093author name stringB D Beynnon
G J Badger
A E Gauthier
F Ertem
M L Roemhildt
P2860cites workUnweighting accelerates tidemark advancement in articular cartilage at the knee joint of ratsQ46211890
Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritisQ46722069
Lipid peroxidation and antioxidant enzymes in synovial fluid of patients with primary and secondary osteoarthritis of the knee jointQ46805543
Biphasic indentation of articular cartilage--I. Theoretical analysis.Q52428577
A novel rat osteoarthrosis model to assess apoptosis and matrix degradation.Q52542178
Biphasic indentation of articular cartilage--II. A numerical algorithm and an experimental study.Q52545412
Osteoarthritis cartilage histopathology: grading and staging.Q53652403
Effects of mechanical loading on the tissues of the rabbit kneeQ57540009
High-resolution MRI and micro-CT in an ex vivo rabbit anterior cruciate ligament transection model of osteoarthritisQ60984213
The articular cartilage after osteotomy for medial gonarthrosis. Biopsies after 2 years in 19 casesQ68050725
Interspecies comparisons of in situ intrinsic mechanical properties of distal femoral cartilageQ70130231
Effects of continuous distraction on cartilage in a moving joint: an investigation on adult rabbitsQ73562674
The effects of static and intermittent compression on nitric oxide production in articular cartilage explantsQ74414367
Evaluation of the rat stifle joint after transection of the cranial cruciate ligament and partial medial meniscectomyQ77850579
Clinical benefit of joint distraction in the treatment of severe osteoarthritis of the ankle: proof of concept in an open prospective study and in a randomized controlled studyQ78505448
Remodeling of articular defects in an animal modelQ80277435
Molecular and histological analysis of a new rat model of experimental knee osteoarthritisQ80656011
Dose-response relationship for exercise on severity of experimental osteoarthritis in rats: a pilot studyQ80792907
Prolonged clinical benefit from joint distraction in the treatment of ankle osteoarthritisQ81889237
Realignment treatment for medial tibiofemoral osteoarthritis: randomised trialQ83539903
Gait alterations in rats following attachment of a device and application of altered knee loadingQ30497460
Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosisQ30500558
Animal models for osteoarthritis: processes, problems and prospectsQ33566417
Altered mechanics of cartilage with osteoarthritis: human osteoarthritis and an experimental model of joint degenerationQ33656698
Comparison of differential biomarkers of osteoarthritis with and without posttraumatic injury in the Hartley guinea pig modelQ33872728
Effects of increased chronic loading on articular cartilage material properties in the lapine tibio-femoral jointQ34069101
Material properties of articular cartilage in the rabbit tibial plateauQ34104307
In situ microindentation for determining local subchondral bone compressive modulus.Q34114957
Baseline articular contact stress levels predict incident symptomatic knee osteoarthritis development in the MOST cohortQ34310168
Animal models of osteoarthritisQ34705018
Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot studyQ35082786
Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritisQ35222605
Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritisQ35769088
Ankle joint distractionQ36317564
Pathomechanisms of cartilage destruction by mechanical injuryQ36327997
Unloading joints to treat osteoarthritis, including joint distractionQ36560170
Effects of specialized footwear on joint loads in osteoarthritis of the kneeQ36841764
Patellar taping and bracing for the treatment of chronic knee pain: a systematic review and meta-analysisQ37046671
Is osteoarthritis a heterogeneous disease that can be stratified into subsets?Q37634998
Basic methods in histopathology of joint tissuesQ37791705
The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the ratQ37791709
Fixation, decalcification, and tissue processing effects on articular cartilage proteoglycansQ38354160
Restoration of Injured or Degenerated Articular CartilageQ39483092
Tissue modification of the lateral compartment of the tibio-femoral joint following in vivo varus loading in the rat.Q39533841
Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritisQ39986023
Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritisQ41939966
Changes induced by chronic in vivo load alteration in the tibiofemoral joint of mature rabbitsQ42221607
Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilageQ43077635
Enhancement of nitric oxide and proteoglycan synthesis due to cyclic tensile strain loaded on chondrocytes attached to fibronectinQ44914201
Bone and cartilage changes following experimental varus or valgus tibial angulationQ44984306
Nitric oxide and G proteins mediate the response of bovine articular chondrocytes to fluid-induced shearQ46162001
P433issue2
P304page(s)346-357
P577publication date2012-11-01
P1433published inOsteoarthritis and CartilageQ7107605
P1476titleChronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint
P478volume21

Reverse relations

cites work (P2860)
Q42074542Changes in in vitro compressive contact stress in the rat tibiofemoral joint with varus loading
Q57148321Early Signs of Bone and Cartilage Changes Induced by Treadmill Exercise in Rats
Q91757328Gait- and postural-alignment-related prognostic factors for hip and knee osteoarthritis: Toward the prevention of osteoarthritis progression
Q37690510Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage
Q36746008Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments
Q38287819Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis.
Q39914895On the Spatiotemporal Material Anisotropy of the Vitreous Body in Tension and Compression
Q97645682Pathogenesis and clinical management of obesity-related knee osteoarthritis: Impact of mechanical loading
Q36393178The collagen microstructural changes of rat menisci and tibiofemoral cartilages under the influence of mechanical loading: An in vitro wear test of whole joints

Search more.