Is osteoarthritis a heterogeneous disease that can be stratified into subsets?

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Is osteoarthritis a heterogeneous disease that can be stratified into subsets? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1007/S10067-009-1301-1
P698PubMed publication ID19924499

P50authorJeffrey DribanQ42671219
P2093author name stringMary F Barbe
Michael R Sitler
Easwaran Balasubramanian
P2860cites workIncidental meniscal findings on knee MRI in middle-aged and elderly personsQ24620297
EULAR Recommendations 2003: an evidence based approach to the management of knee osteoarthritis: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT)Q24674132
Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part IIQ28396036
Radiological assessment of osteo-arthrosisQ29614927
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelinesQ33320085
Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiativeQ33469962
Clinical signs of early osteoarthritis: reproducibility and relation to x ray changes in 541 women in the general populationQ33563712
Etiopathogenesis of osteoarthritisQ34896401
Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritisQ35554303
EULAR report on the use of ultrasonography in painful knee osteoarthritis. Part 1: prevalence of inflammation in osteoarthritisQ35555075
High abundance synovial fluid proteome: distinct profiles in health and osteoarthritisQ35869021
Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study.Q35973947
New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targetsQ36413081
The burden of musculoskeletal disease--a global perspectiveQ36446201
Osteoarthritis of the knee: association between clinical features and MR imaging findingsQ36484251
Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targetsQ36737776
Quadriceps strength and the risk of cartilage loss and symptom progression in knee osteoarthritisQ36843097
Joint space narrowing and Kellgren-Lawrence progression in knee osteoarthritis: an analytic literature synthesisQ37086756
The genetic influence on radiographic osteoarthritis is site specific at the hand, hip and kneeQ37100636
How close are we to having structure-modifying drugs available?Q37237910
Identification of progressors in osteoarthritis by combining biochemical and MRI-based markersQ37350908
Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics.Q37546387
Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factorsQ37594768
Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patientsQ38288322
Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblastsQ38319364
Expression of ICAM-1 by osteoblasts in healthy individuals and in patients suffering from osteoarthritis and osteoporosisQ38338638
Association of health-related quality of life with dual use of prescription and over-the-counter nonsteroidal antiinflammatory drugsQ39324342
Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism AssociationQ39513001
The differential expression of osteoprotegerin (OPG) and receptor activator of nuclear factor kappaB ligand (RANKL) in human osteoarthritic subchondral bone osteoblasts is an indicator of the metabolic state of these disease cellsQ39970700
Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritisQ40262163
Financial cost of osteoarthritis in France. The "COART" France studyQ40381153
Knee and ankle: human joints with different susceptibility to osteoarthritis reveal different cartilage cellularity and matrix synthesis in vitroQ43693595
Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findingsQ46357364
Responder analysis and correlation of outcome measures: pooled results from two identical studies comparing etoricoxib, celecoxib, and placebo in osteoarthritisQ46565841
Lipid peroxidation and antioxidant enzymes in synovial fluid of patients with primary and secondary osteoarthritis of the knee jointQ46805543
Correlation of plasma and synovial fluid osteopontin with disease severity in knee osteoarthritisQ46811152
Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease.Q51767105
Confirmation of two major polyarticular osteoarthritis (POA) phenotypes--differentiation on the basis of joint topography.Q51783426
Phenotyping of chondrocytes in vivo and in vitro using cDNA array technology.Q51921446
Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells.Q52926308
Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis.Q52959492
Glucosamine sulfate in osteoarthritis of the knee.Q53017997
Association between interleukin 1 gene cluster polymorphisms and bilateral distal interphalangeal osteoarthritis.Q54469163
Phenotypic characterization of inflammatory cells from osteoarthritic synovium and synovial fluids.Q54798614
Nonsteroidal antiinflammatory drugs in rheumatoid arthritis and osteoarthritis. Support for the concept of “responders” and “nonresponders”Q57415332
Inflammatory response in patients with active and inactive osteoarthritisQ59645698
The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypesQ60704820
Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis GuidelinesQ73027994
Modification of osteoarthritis by pulsed electromagnetic field--a morphological studyQ73513488
Proteoglycans in the synovial fluid of the temporomandibular joint as an indicator of changes in cartilage metabolism during primary and secondary osteoarthritisQ74165408
Stratification of flare intensity identifies placebo responders in a treatment efficacy trial of patients with osteoarthritisQ74242413
Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritisQ79318170
Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of diseaseQ79360290
Association between radiographic joint space narrowing, function, pain and muscle power in severe osteoarthritis of the kneeQ81082797
MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptomsQ81346471
P433issue2
P921main subjectosteoarthritisQ62736
P304page(s)123-131
P577publication date2009-11-19
P1433published inClinical RheumatologyQ15754927
P1476titleIs osteoarthritis a heterogeneous disease that can be stratified into subsets?
P478volume29

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cites work (P2860)
Q92757104A 12-month prospective exploratory study of muscle and fat characteristics in individuals with mild-to-moderate hip osteoarthritis
Q33755294A Histopathological Scheme for the Quantitative Scoring of Intervertebral Disc Degeneration and the Therapeutic Utility of Adult Mesenchymal Stem Cells for Intervertebral Disc Regeneration
Q30432076A commentary on modelling osteoarthritis pain in small animals
Q47121927Association between ultrasound-detected synovitis and knee pain: a population-based case-control study with both cross-sectional and follow-up data
Q42122306Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis
Q37605100Bearings in Hip Arthroplasty: Joint Registries vs Precision Medicine: Review Article
Q34084915Biochemical comparison of osteoarthritic knees with and without effusion
Q43012050Chronic in vivo load alteration induces degenerative changes in the rat tibiofemoral joint
Q48252716Classification of patients with knee osteoarthritis in clinical phenotypes: Data from the osteoarthritis initiative
Q37308917Clinical Phenotype Classifications Based on Static Varus Alignment and Varus Thrust in Japanese Patients With Medial Knee Osteoarthritis
Q89845962Clinical phenotypes based on clinical prognostic factors in patients with secondary hip osteoarthritis: preliminary findings from a prospective cohort study
Q64120795Combined surgery and chondrocyte cell-sheet transplantation improves clinical and structural outcomes in knee osteoarthritis
Q30934647Distinct subtypes of knee osteoarthritis: data from the Osteoarthritis Initiative
Q48104464Exercise in knee osteoarthritis: do treatment outcomes relate to bone marrow lesions? A randomized trial
Q35617712Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
Q33604814Genetic influences on hand osteoarthritis in Finnish women--a replication study of candidate genes
Q92153098Health Evaluation in the Context of Satisfaction with Medical Services among Patients with Osteoarthritis: Descriptive Cross-Section Survey
Q36161925Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature
Q91871232Identification of knee osteoarthritis disability phenotypes regarding activity limitation: a cluster analysis
Q34033486Identification of phenotypes with different clinical outcomes in knee osteoarthritis: data from the Osteoarthritis Initiative.
Q37691105Intra-articular injection of collagenase in the knee of rats as an alternative model to study nociception associated with osteoarthritis
Q23914570Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder
Q64261899Macrophage proliferation distinguishes 2 subgroups of knee osteoarthritis patients
Q30978918Meniscal extrusion or subchondral damage characterize incident accelerated osteoarthritis: Data from the Osteoarthritis Initiative
Q57168634Modeling and predicting osteoarthritis progression: data from the osteoarthritis initiative
Q64054104Multiple mesenchymal progenitor cell subtypes with distinct functional potential are present within the intimal layer of the hip synovium
Q26781301On the predictive utility of animal models of osteoarthritis
Q60461784Osteoarthritis
Q38108123Post-traumatic osteoarthritis: from mouse models to clinical trials
Q93135737Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis
Q88664709Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort
Q38819017Regenerative approaches for the treatment of early OA.
Q51181091The natural history of radiographic knee osteoarthritis: a fourteen-year population-based cohort study.
Q34782275The potential of multiple synovial-fluid protein-concentration analyses in the assessment of knee osteoarthritis.
Q38867664Using mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.
Q26828365What constitutes an "animal model of osteoarthritis"--the need for consensus?
Q59809992Zhuang Gu Guan Jie Wan: Reasonable Application Can Alleviate the Liver Injury for Osteoarthritis Treatment

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