Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort

scientific article published on 22 May 2018

Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort is …
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scholarly articleQ13442814

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P356DOI10.1016/J.JOCA.2018.05.002
P932PMC publication ID6050083
P698PubMed publication ID29758352

P50authorAndrea LaCroixQ28360453
Jessica L Krok-SchoenQ54342200
Rany M SalemQ79924036
P2093author name stringC B Eaton
A Reiner
C Kooperberg
R Terkeltaub
R D Jackson
A H Shadyab
P2860cites workClinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of HealthQ28288766
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization StudyQ28600936
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant dataQ28742740
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohortsQ29614946
Racial disparities in knee and hip total joint arthroplasty: an 18-year analysis of national Medicare dataQ30667636
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Serum C reactive protein levels and genetic variation in the CRP gene are not associated with the prevalence, incidence or progression of osteoarthritis independent of body mass indexQ34118079
Osteoarthritis: a disease of the joint as an organQ34258870
Genome-wide association and population genetic analysis of C-reactive protein in African American and Hispanic American womenQ34297002
Epidemiology of knee and hip arthroplasty: a systematic reviewQ34974331
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levelsQ35138365
Biomarkers of incident radiographic knee osteoarthritis: do they vary by chronic knee symptoms?Q35146138
No association between markers of inflammation and osteoarthritis of the hands and kneesQ35344741
Increased serum C reactive protein may reflect events that precede radiographic progression in osteoarthritis of the kneeQ35548883
Severity and extent of osteoarthritis and low grade systemic inflammation as assessed by high sensitivity C reactive proteinQ35553756
Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkersQ36225451
Inflammation in osteoarthritisQ37608903
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Role of proinflammatory cytokines in the pathophysiology of osteoarthritisQ37814044
Circulating C reactive protein in osteoarthritis: a systematic review and meta-analysisQ38173342
The role of innate immunity in osteoarthritis: when our first line of defense goes on the offensiveQ38320224
Risk factors for the incidence and progression of radiographic knee osteoarthritisQ39119596
Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study GroupQ39513392
Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritisQ40262163
Editorial: inflammatory activity in symptomatic knee osteoarthritis: not all inflammation is localQ42374928
C-reactive protein levels among women of various ethnic groups living in the United States (from the Women's Health Study).Q43800238
C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort studyQ43945113
Linkage disequilibrium patterns of the human genome across populationsQ46420212
The C-reactive protein but not erythrocyte sedimentation rate is associated with clinical severity in patients with osteoarthritis of the knee or hip.Q50940200
Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive diseaseQ73284286
Increased serum C-reactive protein levels by immunonephelometry in patients with rapidly destructive hip osteoarthritisQ77920324
C-reactive protein as a biomarker of emergent osteoarthritisQ78649895
Allelic variation at the C-reactive protein gene associates to both hand osteoarthritis severity and serum high sensitive C-reactive protein levels in the GARP studyQ80137298
Cross-sectional association of 10 molecular markers of bone, cartilage, and synovium with disease activity and radiological joint damage in patients with hip osteoarthritis: the ECHODIAH cohortQ81597304
P433issue8
P921main subjectosteoarthritisQ62736
P304page(s)1038-1044
P577publication date2018-05-22
P1433published inOsteoarthritis and CartilageQ7107605
P1476titleProspective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort
P478volume26

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Q92572683Multiple plasma metals, genetic risk and serum C-reactive protein: A metal-metal and gene-metal interaction studycites workP2860

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