| scholarly article | Q13442814 |
| P2093 | author name string | James C Samuelson | |
| Shuang-yong Xu | |||
| P2860 | cites work | Structure and function of type II restriction endonucleases | Q24555230 |
| Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution | Q27621185 | ||
| Refinement of Eco RI endonuclease crystal structure: a revised protein chain tracing | Q27685433 | ||
| Structure of Bam HI endonuclease bound to DNA: partial folding and unfolding on DNA binding | Q27729783 | ||
| Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis | Q27747308 | ||
| Role of protein-induced bending in the specificity of DNA recognition: crystal structure of EcoRV endonuclease complexed with d(AAAGAT) + d(ATCTT) | Q27749068 | ||
| Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts | Q27765116 | ||
| Randomization of genes by PCR mutagenesis | Q33198019 | ||
| How the EcoRI endonuclease recognizes and cleaves DNA. | Q34541915 | ||
| Generation of large libraries of random mutants in Bacillus subtilis by PCR-based plasmid multimerization | Q36877947 | ||
| Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants | Q38295212 | ||
| Crosslinking the EcoRV restriction endonuclease across the DNA-binding site reveals transient intermediates and conformational changes of the enzyme during DNA binding and catalytic turnover | Q38331219 | ||
| Changing the hydrogen-bonding potential in the DNA binding site of EcoRI by site-directed mutagenesis drastically reduces the enzymatic activity, not, however, the preference of this restriction endonuclease for cleavage within the site-GAATTC-. | Q38344996 | ||
| Inducible DNA repair systems | Q39826678 | ||
| The 'endo-blue method' for direct cloning of restriction endonuclease genes in E. coli. | Q40229405 | ||
| Direct selection of binding proficient/catalytic deficient variants of BamHI endonuclease | Q40399034 | ||
| Cloning and characterization of the Bg/II restriction-modification system reveals a possible evolutionary footprint | Q42651983 | ||
| Temperature-sensitive mutants of the EcoRI endonuclease | Q44548743 | ||
| Mutational analysis of the function of Met137 and Ile197, two amino acids implicated in sequence-specific DNA recognition by the EcoRI endonuclease. | Q52530957 | ||
| Substrate recognition by the EcoRI endonuclease. | Q54720062 | ||
| Towards the design of rare cutting restriction endonucleases: using directed evolution to generate variants of EcoRV differing in their substrate specificity by two orders of magnitude | Q56902829 | ||
| On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target | Q57267689 | ||
| Protein engineering of the restriction endonuclease EcoRV . Structure-guided design of enzyme variants that recognize the base pairs flanking the recognition site | Q57267701 | ||
| SOS induction as an in vivo assay of enzyme-DNA interactions | Q67996221 | ||
| Effects of surrounding sequence on the suppression of nonsense codons | Q72695521 | ||
| Genetic analysis of the base-specific contacts of BamHI restriction endonuclease | Q77901522 | ||
| A mutant of BamHI restriction endonuclease which requires N6-methyladenine for cleavage | Q77901524 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | directed evolution | Q440681 |
| P304 | page(s) | 673-683 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Journal of Molecular Biology | Q925779 |
| P1476 | title | Directed evolution of restriction endonuclease BstYI to achieve increased substrate specificity | |
| P478 | volume | 319 |
| Q34482204 | A measure of the broad substrate specificity of enzymes based on 'duplicate' catalytic residues |
| Q28750208 | Alteration of Sequence Specificity of the Type IIS Restriction Endonuclease BtsI |
| Q24671370 | Catalytic domain of restriction endonuclease BmrI as a cleavage module for engineering endonucleases with novel substrate specificities |
| Q33585828 | Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases |
| Q45996974 | Conformational transitions as determinants of specificity for the DNA methyltransferase EcoRI. |
| Q42859214 | Context dependence between subdomains in the DNA binding interface of the I-CreI homing endonuclease |
| Q35539178 | Crystallization and preliminary crystallographic analysis of the type IIL restriction enzyme MmeI in complex with DNA |
| Q25257169 | Engineering a rare-cutting restriction enzyme: genetic screening and selection of NotI variants |
| Q55359800 | Engineering altered protein-DNA recognition specificity. |
| Q44356433 | Engineering of restriction endonucleases: using methylation activity of the bifunctional endonuclease Eco57I to select the mutant with a novel sequence specificity |
| Q35207823 | Engineering proteins that bind, move, make and break DNA. |
| Q36802600 | Evolution of sequence specificity in a restriction endonuclease by a point mutation |
| Q24669929 | Generation of DNA cleavage specificities of type II restriction endonucleases by reassortment of target recognition domains |
| Q31091659 | In vitro selection of restriction endonucleases by in vitro compartmentalization |
| Q38353346 | Isolation of BsoBI restriction endonuclease variants with altered substrate specificity |
| Q33222949 | Laboratory-directed protein evolution |
| Q36909769 | Massively parallel characterization of restriction endonucleases |
| Q31120721 | Milestones in directed enzyme evolution. |
| Q27652792 | Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases |
| Q31155398 | Optimising enzyme function by directed evolution. |
| Q36497080 | Rational design of a chimeric endonuclease targeted to NotI recognition site |
| Q36280611 | Rational engineering of sequence specificity in R.MwoI restriction endonuclease |
| Q42072101 | Rational engineering of type II restriction endonuclease DNA binding and cleavage specificity |
| Q37991511 | Restriction endonucleases: natural and directed evolution |
| Q34323730 | Screening for catalytically active Type II restriction endonucleases using segregation-induced methylation deficiency |
| Q35991119 | Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities. |
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