Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase

scientific article published on 6 November 2017

Key amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1711542114
P932PMC publication ID5703305
P698PubMed publication ID29109294

P2093author name stringWolf T Pecher
Priya DasSarma
Shiladitya DasSarma
Jong-Myoung Kim
Ram Karan
Victoria J Laye
P2860cites workTrimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactoseQ27639594
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Evolutionary convergence in adaptation of proteins to temperature: A4-lactate dehydrogenases of Pacific damselfishes (Chromis spp.).Q30336309
A new understanding of how temperature affects the catalytic activity of enzymesQ33606578
Understanding the adaptation of Halobacterium species NRC-1 to its extreme environment through computational analysis of its genome sequenceQ34094195
Function and biotechnology of extremophilic enzymes in low water activityQ34266261
LacZ β-galactosidase: structure and function of an enzyme of historical and molecular biological importanceQ34301945
Psychrophilic enzymes: hot topics in cold adaptationQ34307568
Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarcticaQ34335706
Key microbial drivers in Antarctic aquatic environmentsQ34444590
Halophiles and their enzymes: negativity put to good use.Q34480329
Cloning, overexpression, purification, and characterization of a polyextremophilic β-galactosidase from the Antarctic haloarchaeon Halorubrum lacusprofundiQ34548717
Adaptation of enzymes to temperature: searching for basic "strategies".Q35950710
Do all backbone polar groups in proteins form hydrogen bonds?Q36152610
Molecular adaptations to psychrophily: the impact of 'omic' technologiesQ37774451
Supercharging proteins can impart unusual resilienceQ39273315
Psychrophilic enzymes: molecular basis of cold adaptationQ41670073
Thermostable beta-galactosidase from an extreme thermophile, Thermus sp. A4: enzyme purification and characterization, and gene cloning and sequencingQ43025757
The role of internal packing interactions in determining the structure and stability of a proteinQ44077439
Terrestrial models for extraterrestrial life: methanogens and halophiles at Martian temperaturesQ58332208
Halobacterium lacusprofundi sp. nov., a Halophilic Bacterium Isolated from Deep Lake, AntarcticaQ58425343
P433issue47
P407language of work or nameEnglishQ1860
P1104number of pages6
P304page(s)12530-12535
P577publication date2017-11-06
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleKey amino acid residues conferring enhanced enzyme activity at cold temperatures in an Antarctic polyextremophilic β-galactosidase
P478volume114

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cites work (P2860)
Q49497270An Antarctic Extreme Halophile and Its Polyextremophilic Enzyme: Effects of Perchlorate Salts
Q62772968Early evolution of purple retinal pigments on Earth and implications for exoplanet biosignatures
Q90232603Enzymes from Marine Polar Regions and Their Biotechnological Applications
Q93088639Establishment of mesophilic-like catalytic properties in a thermophilic enzyme without affecting its thermal stability
Q64060311Genome Sequence and Methylation Patterns of sp. Strain BOL3-1, the First Haloarchaeon Isolated and Cultured from Salar de Uyuni, Bolivia
Q92024697Towards Rational Computational Engineering of Psychrophilic Enzymes

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