Characterization of site-specific O-glycan structures within the mucin-like domain of alpha-dystroglycan from human skeletal muscle

scientific article published on 27 May 2010

Characterization of site-specific O-glycan structures within the mucin-like domain of alpha-dystroglycan from human skeletal muscle is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/GLYCOB/CWQ082
P698PubMed publication ID20507882
P5875ResearchGate publication ID44635494

P2093author name stringGöran Larson
Jonas Nilsson
Johanna Nilsson
Ammi Grahn
P2860cites workA comparative study of alpha-dystroglycan glycosylation in dystroglycanopathies suggests that the hypoglycosylation of alpha-dystroglycan does not consistently correlate with clinical severityQ24321993
Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin alpha2 deficiency and abnormal glycosylation of alpha-dystroglycanQ24535942
POMT2 mutations cause alpha-dystroglycan hypoglycosylation and Walker-Warburg syndromeQ24674153
Dystroglycan is a binding protein of laminin and merosin in peripheral nerveQ28238540
Refining genotype phenotype correlations in muscular dystrophies with defective glycosylation of dystroglycanQ28249364
Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localizationQ28257696
Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrixQ28296676
Spectrum of brain changes in patients with congenital muscular dystrophy and FKRP gene mutationsQ28297242
Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11Q28589413
Regulation of mammalian protein O-mannosylation: preferential amino acid sequence for O-mannose modificationQ33284581
O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.Q34090655
The complexities of dystroglycanQ34134645
Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin bindingQ34405965
Mutational and functional analysis of Large in a novel CHO glycosylation mutantQ34983110
Glycosylation in congenital muscular dystrophiesQ35596665
Dystroglycan: from biosynthesis to pathogenesis of human disease.Q36367346
Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activatorQ38309412
Enhanced laminin binding by alpha-dystroglycan after enzymatic deglycosylationQ38326990
Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with lamininQ38349218
Core 1 glycans on alpha-dystroglycan mediate laminin-induced acetylcholine receptor clustering but not laminin bindingQ38350844
Initiation of mammalian O-mannosylation in vivo is independent of a consensus sequence and controlled by peptide regions within and upstream of the alpha-dystroglycan mucin domainQ39985380
Glycosylation of recombinant proteins: problems and prospectsQ40534646
Differential Vicia villosa agglutinin reactivity identifies three distinct dystroglycan complexes in skeletal muscleQ40791672
Getting the glycosylation right: implications for the biotechnology industryQ41176922
POMT2 mutation in a patient with 'MEB-like' phenotype.Q41919601
The expanding phenotype of POMT1 mutations: from Walker-Warburg syndrome to congenital muscular dystrophy, microcephaly, and mental retardation.Q41919724
Post-translational disruption of dystroglycan-ligand interactions in congenital muscular dystrophiesQ42524150
Mutations in the FKRP gene can cause muscle-eye-brain disease and Walker-Warburg syndrome.Q43073716
The phenotype of limb-girdle muscular dystrophy type 2IQ44411539
LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies.Q47375901
Phenotypic spectrum associated with mutations in the fukutin-related protein geneQ48350456
Structural analysis of sequences O-linked to mannose reveals a novel Lewis X structure in cranin (dystroglycan) purified from sheep brainQ48401243
Tissue-specific heterogeneity in alpha-dystroglycan sialoglycosylation. Skeletal muscle alpha-dystroglycan is a latent receptor for Vicia villosa agglutinin b4 masked by sialic acid modificationQ48634703
P433issue9
P304page(s)1160-1169
P577publication date2010-05-27
P1433published inGlycobiologyQ5572596
P1476titleCharacterization of site-specific O-glycan structures within the mucin-like domain of alpha-dystroglycan from human skeletal muscle
P478volume20

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cites work (P2860)
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