Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization

scientific article published on 5 June 2009

Activation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DB08-1293
P932PMC publication ID2731526
P698PubMed publication ID19502419
P5875ResearchGate publication ID26272439

P50authorMeghan KellyQ59542585
Marie-Soleil GauthierQ64039239
Asish K SahaQ43064667
Neil B RudermanQ43064674
P2860cites workInterleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal MuscleQ58449836
Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen contentQ58818196
Increase in interstitial interleukin-6 of human skeletal muscle with repetitive low-force exerciseQ59329763
Determination of glycogen in small tissue samplesQ71415797
A malonyl-CoA fuel-sensing mechanism in muscle: effects of insulin, glucose, and denervationQ72005814
Interleukin 1beta and interleukin 6, but not tumor necrosis factor alpha, inhibit insulin-stimulated glycogen synthesis in rat hepatocytesQ74530390
IL-6 increases muscle insulin sensitivity only at superphysiological levelsQ79843016
Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentrationQ22241965
Principles of interleukin (IL)-6-type cytokine signalling and its regulationQ24530173
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinaseQ28215845
Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscleQ28238008
Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytesQ28570462
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exerciseQ28581480
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolismQ29617261
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alphaQ29620443
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistanceQ33941406
Muscle-derived interleukin-6: mechanisms for activation and possible biological rolesQ34146938
Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C deltaQ34161086
Management of cellular energy by the AMP-activated protein kinase systemQ34209246
The paradigm of IL-6: from basic science to medicineQ34731226
AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise.Q35178619
Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6.Q36072891
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndromeQ36666161
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevanceQ36711158
Function of mitochondrial Stat3 in cellular respirationQ37378567
AMP-activated protein kinase phosphorylates transcription factors of the CREB familyQ40038541
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinaseQ40227253
Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cellsQ40328526
Interleukin-6 stimulates lipolysis and fat oxidation in humansQ42169595
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjectsQ42797512
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissuesQ42805365
Malonyl-CoA and the regulation of fatty acid oxidation in soleus muscleQ42991497
Interleukin-6-deficient mice develop mature-onset obesityQ43851625
Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interactionQ44166573
Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinaseQ44493386
Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1alpha in rat muscleQ44821884
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exerciseQ44953597
Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contractionQ44953893
Acute central infusion of leptin modulates fatty acid mobilization by affecting lipolysis and mRNA expression for uncoupling proteinsQ45285225
Interleukin-6 stimulates lipolysis in porcine adipocytesQ46240847
Reduced exercise endurance in interleukin-6-deficient miceQ48013970
CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.Q48588727
Hypertension produced by reductions in uterine perfusion in the pregnant rat: role of interleukin 6.Q51139503
UCP-3 expression in skeletal muscle: effects of exercise, hypoxia, and AMP-activated protein kinase.Q51554314
Role of interleukin-6 in the control of DNA synthesis of hepatocytes: involvement of PKC, p44/42 MAPKs, and PPARdelta.Q53430282
Lymphocyte and cytokines after short periods of exercise.Q53468266
Effect of exercise, training, and glycogen availability on IL-6 receptor expression in human skeletal muscleQ56240276
Substantial elevation of interleukin-6 concentration in peritendinous tissue, in contrast to muscle, following prolonged exercise in humansQ57024665
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
P304page(s)1953-1960
P577publication date2009-06-05
P1433published inDiabetesQ895262
P1476titleActivation of AMP-activated protein kinase by interleukin-6 in rat skeletal muscle: association with changes in cAMP, energy state, and endogenous fuel mobilization
P478volume58

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