Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease

scientific article published on 25 July 2013

Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2013.00212
P932PMC publication ID3722515
P698PubMed publication ID23898333
P5875ResearchGate publication ID253340104

P2093author name stringTheresa L Whiteside
Edwin K Jackson
P2860cites workAdenosine receptors: therapeutic aspects for inflammatory and immune diseasesQ24651475
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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppressionQ29615344
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Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cellsQ33748026
Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppressionQ33903025
Adenosine and prostaglandin E2 cooperate in the suppression of immune responses mediated by adaptive regulatory T cellsQ34107172
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
Type 1 T regulatory cells.Q34448429
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The prognostic value of FoxP3+ tumor-infiltrating lymphocytes in cancer: a critical review of the literatureQ34637571
Regulatory T cells negatively affect IL-2 production of effector T cells through CD39/adenosine pathway in HIV infectionQ34711777
Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers.Q35559050
AMP is an adenosine A1 receptor agonistQ35773917
The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancerQ35858991
Functional regulatory T cells produced by inhibiting cyclic nucleotide phosphodiesterase type 3 prevent allograft rejection.Q35875359
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cellsQ35995214
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulationQ36367099
Drug therapy aimed at adenylyl cyclase to regulate cyclic nucleotide signalingQ36612183
Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines.Q36787548
The tumor microenvironment and its role in promoting tumor growthQ36946019
Adenosine production by human B cells and B cell-mediated suppression of activated T cellsQ36983750
Immune modulation of T-cell and NK (natural killer) cell activities by TEXs (tumour-derived exosomes)Q37040486
Compositions for treatment of cancer and inflammationQ37090388
Inhibition of T cell and natural killer cell function by adenosine and its contribution to immune evasion by tumor cells (Review).Q37091784
Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving targetQ37111968
Is FOXP3 a bona fide marker for human regulatory T cells?Q37131913
Expression of RORγt marks a pathogenic regulatory T cell subset in human colon cancerQ37146190
Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expressionQ37245083
Indoleamine 2,3-dioxygenase-expressing mature human monocyte-derived dendritic cells expand potent autologous regulatory T cells.Q37268984
Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?Q37493607
Adenylyl cyclases as innovative therapeutic goals.Q37564706
CD4 (+)CD25 (+)Foxp3 (+) regulatory T cells and hematologic malignanciesQ37762036
Regulatory T cells in tumor immunityQ37762224
Extracellular adenosine triphosphate and adenosine in cancer.Q37775889
Phenotypical and functional specialization of FOXP3+ regulatory T cellsQ37832385
Distinct regulatory CD4+T cell subsets; differences between naïve and antigen specific T regulatory cellsQ37917132
Prognostic and predictive impact of intra- and peritumoral immune infiltratesQ37918676
The role of anti-inflammatory drugs in colorectal cancerQ38047412
Foxp3 expression in human cancer cells.Q38524958
Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinomaQ40079450
Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironmentQ40177099
T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposisQ40909943
Receptor desensitization and blockade of the suppressive effects of prostaglandin E2 and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytesQ41832380
T regulatory type 1 cells in squamous cell carcinoma of the head and neck: mechanisms of suppression and expansion in advanced diseaseQ41888065
Ecto-5'-nucleotidase: Structure function relationshipsQ42008606
Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsetsQ42066000
Modulation of tryptophan catabolism by regulatory T cells.Q44632333
Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patientsQ46312545
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase.Q46490849
Cooperation of adenosine and prostaglandin E2 (PGE2) in amplification of cAMP-PKA signaling and immunosuppressionQ46713114
The frequency and suppressor function of CD4+CD25highFoxp3+ T cells in the circulation of patients with squamous cell carcinoma of the head and neckQ46920694
Distinctive role of CCR7 in migration and functional activity of naive- and effector/memory-like Treg subsets.Q51975593
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.Q51995543
Regulatory T cells stay on course.Q52889469
Expression of Helios in Peripherally Induced Foxp3+ Regulatory T CellsQ56888758
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor zeta-chain and induce a regulatory phenotype in naive T cellsQ56902123
Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal CancerQ56932821
Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patientsQ57220173
Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late RelapseQ58211903
Transient expression of FOXP3 in human activated nonregulatory CD4+ T cellsQ58234949
Regulatory T cells in cancerQ84073243
Expanded subpopulation of FoxP3+ T regulatory cells in renal cell carcinoma co-express Helios, indicating they could be derived from natural but not induced TregsQ84099411
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)212
P577publication date2013-07-25
P1433published inFrontiers in ImmunologyQ27723748
P1476titleAdenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease
P478volume4

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cites work (P2860)
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