Specific siRNA targeting the receptor for advanced glycation end products inhibits experimental hepatic fibrosis in rats

scientific article published on 24 April 2008

Specific siRNA targeting the receptor for advanced glycation end products inhibits experimental hepatic fibrosis in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS9040638
P932PMC publication ID2635697
P698PubMed publication ID19325776
P5875ResearchGate publication ID24238368

P2093author name stringNai-Feng Liu
Jin-Rong Xia
Nai-Xun Zhu
P2860cites work[Hepatic stellate cells and oxidative stress]Q53544677
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IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammationQ59054264
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Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)Q28366662
N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expressionQ28645594
Liver fibrosisQ29547449
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Liver fibrosisQ34005628
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Advanced glycation end-products: a reviewQ34196489
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Expression of matrix metalloproteinases and their inhibitors during the resorption of schistosome egg-induced fibrosis in praziquantel-treated miceQ39466912
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CD40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cellsQ40804865
Rel/NF-kappa B and I kappa B proteins: an overviewQ41595423
Modified synthetic siRNA targeting tissue inhibitor of metalloproteinase-2 inhibits hepatic fibrogenesis in ratsQ42162327
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Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.Q43565214
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in ratsQ43720079
Markedly elevated levels of plasma advanced glycation end products in patients with liver cirrhosis - amelioration by liver transplantation.Q43862536
Growth hormone increases lung NF-kappaB activation and lung microvascular injury induced by lipopolysaccharide in rats.Q44642527
Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.Q45212249
Increased protein glycation in cirrhosis and therapeutic strategies to prevent it.Q46613224
Elevation of Nepsilon-(carboxymethyl)lysine-modified advanced glycation end products in chronic liver disease is an indicator of liver cirrhosisQ46830346
Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in miceQ47214457
AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE conceptQ47864019
Myofibroblast transdifferentiation of mesothelial cells is mediated by RAGE and contributes to peritoneal fibrosis in uraemia.Q49082283
Activation of the Receptor for Advanced Glycation End Products Triggers a p21 -dependent Mitogen-activated Protein Kinase Pathway Regulated by Oxidant StressQ50180621
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)638-661
P577publication date2008-04-24
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleSpecific siRNA targeting the receptor for advanced glycation end products inhibits experimental hepatic fibrosis in rats
P478volume9

Reverse relations

cites work (P2860)
Q42223709Ameliorative Effects of Nilotinib on CCl4 Induced Liver Fibrosis Via Attenuation of RAGE/HMGB1 Gene Expression and Oxidative Stress in Rat.
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Q43506762Receptor for advanced glycation endproducts (RAGE) is a key regulator of oval cell activation and inflammation-associated liver carcinogenesis in mice.
Q34734165Retracted: High Mobility Group Box-1 Promotes the Proliferation and Migration of Hepatic Stellate Cells via TLR4-Dependent Signal Pathways of PI3K/Akt and JNK
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Q35870539Small interfering RNA targeting receptor for advanced glycation end products suppresses the generation of proinflammatory cytokines
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