The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase.

scientific article published on 27 October 2008

The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M801816200
P932PMC publication ID2602891
P698PubMed publication ID18955496

P50authorSarah M TheissenQ79712591
P2093author name stringMichael J Caplan
Thomas Ludwig
Michael J Morton
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A di-leucine motif mediates endocytosis and basolateral sorting of macrophage IgG Fc receptors in MDCK cells.Q37633898
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Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cellsQ40213124
O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).Q40289813
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Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instabilityQ40425742
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The dileucine motif at the COOH terminus of human multidrug resistance P-glycoprotein is important for folding but not activityQ40492449
Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cellsQ40598609
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A dileucine motif targets E-cadherin to the basolateral cell surface in Madin-Darby canine kidney and LLC-PK1 epithelial cells.Q40811578
Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.Q40886684
Tyrosine-based membrane protein sorting signals are differentially interpreted by polarized Madin-Darby canine kidney and LLC-PK1 epithelial cells.Q41005449
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Sialic acids as ligands in recognition phenomena.Q41382062
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Cytoplasmic tail-dependent internalization of membrane-type 1 matrix metalloproteinase is important for its invasion-promoting activity.Q42952060
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Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinaseQ47325337
Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domainQ47850733
A dileucine sequence and an upstream glutamate residue in the intracellular carboxyl terminus of the vasopressin V2 receptor are essential for cell surface transport in COS.M6 cells.Q52993336
Functional measurement of local proteolytic activity in living cells of invasive and non-invasive tumors.Q53884383
Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chainsQ71763363
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The cytoplasmic carboxy-terminal amino acid determines the subcellular localization of proTGF-(alpha) and membrane type matrix metalloprotease (MT1-MMP)Q74482447
MT1-MMP: an enzyme with multidimensional regulationQ80382794
P433issue51
P407language of work or nameEnglishQ1860
P921main subjectglycosylationQ898365
P304page(s)35410-35418
P577publication date2008-10-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase
P478volume283

Reverse relations

cites work (P2860)
Q34395979Detection of the heterogeneous O-glycosylation profile of MT1-MMP expressed in cancer cells by a simple MALDI-MS method
Q35763112Dileucine and PDZ-binding motifs mediate synaptic adhesion-like molecule 1 (SALM1) trafficking in hippocampal neurons
Q34291116Functional analysis of a breast cancer-associated mutation in the intracellular domain of the metalloprotease ADAM12
Q26745510Glycosylation of matrix metalloproteases and tissue inhibitors: present state, challenges and opportunities
Q24337919Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen
Q30527787N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods
Q93379727Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1
Q39682060Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP
Q42617197The extracellular matrix remodeled: Interdependency of matrix proteolysis, cell adhesion, and force sensing
Q34745166The polarization of the G-protein activated potassium channel GIRK5 to the vegetal pole of Xenopus laevis oocytes is driven by a di-leucine motif

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