Degradation of leucine zipper-positive isoform of MYPT1 may contribute to development of nitrate tolerance

scientific article published on 25 November 2009

Degradation of leucine zipper-positive isoform of MYPT1 may contribute to development of nitrate tolerance is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CVR/CVP376
P698PubMed publication ID19939965
P5875ResearchGate publication ID40033187

P2093author name stringXiaoxu Zheng
Huijuan Ma
Lei Ying
Yuansheng Gao
Dou Dou
Xiaoxing Yu
Yixuan Guo
P2860cites workLong-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome.Q53024062
Captopril prevents myosin light chain phosphatase isoform switching to preserve normal cGMP-mediated vasodilatation.Q53614139
An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivationQ24535741
Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase IalphaQ28138136
Myosin light chain phosphatase: subunit composition, interactions and regulationQ28274342
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystinQ28300614
Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET-cyclic GMPSQ28569425
Proteasome inhibitors: valuable new tools for cell biologistsQ29620573
Acceleration of myosin light chain dephosphorylation and relaxation of smooth muscle by telokin. Synergism with cyclic nucleotide-activated kinaseQ30471988
Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expressionQ33428533
Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-toleranceQ34194262
Interactions between the leucine-zipper motif of cGMP-dependent protein kinase and the C-terminal region of the targeting subunit of myosin light chain phosphataseQ35026712
Clinical pharmacokinetics and pharmacodynamics of glyceryl trinitrate and its metabolitesQ35072069
Cardioprotective effects of glyceryl trinitrate: beyond vascular nitrate toleranceQ35996876
Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veinsQ36171316
Explaining the phenomenon of nitrate toleranceQ36272905
Function of cGMP-dependent protein kinases as revealed by gene deletion.Q36350063
Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteriesQ36456848
Bioactivation of nitroglycerin by the mitochondrial aldehyde dehydrogenaseQ36630533
Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the relationship of structure to enzymic activityQ39900628
Contribution of aldehyde dehydrogenase to mitochondrial bioactivation of nitroglycerin: evidence for the activation of purified soluble guanylate cyclase through direct formation of nitric oxide.Q40514133
Structure and function of cyclic nucleotide-dependent protein kinasesQ40660658
Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.Q42124934
Role of L-arginine in the vascular actions and development of tolerance to nitroglycerinQ42487860
Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate toleranceQ42544768
Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta.Q43594098
Role of myosin phosphatase isoforms in cGMP-mediated smooth muscle relaxationQ43696129
Upregulation of phosphodiesterase 1A1 expression is associated with the development of nitrate toleranceQ43790689
Functional and biochemical analysis of endothelial (dys)function and NO/cGMP signaling in human blood vessels with and without nitroglycerin pretreatmentQ43913687
Unzipping the Role of Myosin Light Chain Phosphatase in Smooth Muscle Cell RelaxationQ44608924
Role of Mitochondrial Aldehyde Dehydrogenase in Nitrate ToleranceQ44628553
Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathwayQ44760490
Vascular reactivity in heart failure: role of myosin light chain phosphataseQ45024938
Gene expression profiles of vascular smooth muscle show differential expression of mitogen-activated protein kinase pathways during captopril therapy of heart failureQ46640585
Inhibition of phosphodiesterase 5 selectively reverses nitrate tolerance in the venous circulationQ46837601
Myosin phosphatase isoform switching in vascular smooth muscle development.Q46852468
Depletion of arterial L-arginine causes reversible tolerance to endothelium-dependent relaxation.Q50885317
cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery.Q51041188
P433issue1
P304page(s)151-159
P577publication date2009-11-25
P1433published inCardiovascular ResearchQ4642329
P1476titleDegradation of leucine zipper-positive isoform of MYPT1 may contribute to development of nitrate tolerance
P478volume86

Reverse relations

cites work (P2860)
Q40301580Altered reactivity of tertiary mesenteric arteries following acute myocardial ischemia
Q36453941Endothelium-Independent Hypoxic Contraction Is Prevented Specifically by Nitroglycerin via Inhibition of Akt Kinase in Porcine Coronary Artery
Q48012184Endothelium-independent hypoxic contraction of porcine coronary arteries may be mediated by activation of phosphoinositide 3-kinase/Akt pathway
Q82156130Heterogeneity in relaxation of different sized porcine coronary arteries to nitrovasodilators: role of PKG and MYPT1
Q42060151Hypoxia modulates the expression of leucine zipper-positive MYPT1 and its interaction with protein kinase G and Rho kinases in pulmonary arterial smooth muscle cells
Q33994665Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery
Q26753129Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders
Q37887771Nitric oxide: a guardian for vascular grafts?
Q54618994Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide.
Q53085161The role of pulmonary vascular contractile protein expression in pulmonary arterial hypertension.
Q55026322The vasodilatory effect of sulfur dioxide via SGC/cGMP/PKG pathway in association with sulfhydryl-dependent dimerization.

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