| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1152/PHYSREV.00015.2005 |
| P698 | PubMed publication ID | 16371594 |
| P50 | author | Robert Feil | Q41774968 |
| P2093 | author name string | Hofmann F | |
| Kleppisch T | |||
| Schlossmann J | |||
| P2860 | cites work | The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for nitric oxide-mediated desensitization. Independent modulation of Tp alpha signaling by nitric oxide and prostacyclin. | Q44608900 |
| P433 | issue | 1 | |
| P304 | page(s) | 1-23 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Physiological Reviews | Q1091827 |
| P1476 | title | Function of cGMP-dependent protein kinases as revealed by gene deletion | |
| P478 | volume | 86 |
| Q33806987 | 'Foraging' for a place to lay eggs: A genetic link between foraging behaviour and oviposition preferences |
| Q33653633 | (D)-Amino acid analogues of DT-2 as highly selective and superior inhibitors of cGMP-dependent protein kinase Ialpha |
| Q33655686 | 8-pCPT-cGMP stimulates alphabetagamma-ENaC activity in oocytes as an external ligand requiring specific nucleotide moieties |
| Q48304000 | A cGMP-dependent protein kinase (PKG) controls synaptic transmission tolerance to acute oxidative stress at the Drosophila larval neuromuscular junction |
| Q34532151 | A genetic screen for olfactory habituation mutations in Drosophila: analysis of novel foraging alleles and an underlying neural circuit |
| Q51112525 | A genetically encoded pore for the stochastic detection of a protein kinase. |
| Q37638406 | A new Rac/PAK/GC/cGMP signaling pathway |
| Q37429047 | A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle. |
| Q42109947 | A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading |
| Q92214405 | Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways |
| Q22241964 | Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior |
| Q36678534 | Alpha1 soluble guanylyl cyclase (sGC) splice forms as potential regulators of human sGC activity |
| Q34018051 | Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse |
| Q37196730 | Altered contractile phenotypes of intestinal smooth muscle in mice deficient in myosin phosphatase target subunit 1 |
| Q36638818 | Anemia and splenomegaly in cGKI-deficient mice |
| Q43067878 | Aromatic L-amino acid decarboxylase phosphorylation and activation by PKGIalpha in vitro |
| Q35060436 | B-type natriuretic peptide-induced delayed modulation of TRPV1 and P2X3 receptors of mouse trigeminal sensory neurons |
| Q52880204 | Bifurcation of axons from cranial sensory neurons is disabled in the absence of Npr2-induced cGMP signaling. |
| Q38098831 | Biophysical techniques for detection of cAMP and cGMP in living cells |
| Q50797130 | Bladder outlet obstruction triggers neural plasticity in sensory pathways and contributes to impaired sensitivity in erectile dysfunction. |
| Q38942004 | Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization |
| Q37297849 | Brain natriuretic peptide suppresses pain induced by BmK I, a sodium channel-specific modulator, in rats. |
| Q34304206 | C-type natriuretic peptide slows down wound healing but promotes angiogenesis in SKH1-hr hairless mice |
| Q28539361 | Catalytic activity of cGMP-dependent protein kinase type I in intact cells is independent of N-terminal autophosphorylation |
| Q39910050 | Causal network analysis of head and neck keloid tissue identifies potential master regulators |
| Q34374837 | Cell membrane disruption stimulates NO/PKG signaling and potentiates cell membrane repair in neighboring cells |
| Q33784953 | Characterisation of the circulating acellular proteome of healthy sheep using LC-MS/MS-based proteomics analysis of serum. |
| Q54510490 | Characterization of nitric oxide signaling pathways in the mouse retina. |
| Q35289534 | Chronic nicotine treatment enhances vascular smooth muscle relaxation in rats. |
| Q27667600 | Co-Crystal Structures of PKG Iβ (92–227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding |
| Q37029494 | Concepts of neural nitric oxide-mediated transmission |
| Q51828997 | Context-dependent expression of the foraging gene in field colonies of ants: the interacting roles of age, environment and task. |
| Q34336542 | Correlative intravital imaging of cGMP signals and vasodilation in mice. |
| Q50199410 | Crosstalk of cyclic GMP dependent kinase I and BMP signaling. |
| Q27684845 | Crystal Structure of the cGMP-dependent Protein Kinase II Leucine Zipper and Rab11b Protein Complex Reveals Molecular Details of G-kinase-specific Interactions |
| Q41530818 | Cyclic GMP kinase I modulates glucagon release from pancreatic α-cells |
| Q42613297 | Cyclic GMP kinase and RhoA Ser188 phosphorylation integrate pro- and antifibrotic signals in blood vessels |
| Q37420916 | Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics |
| Q41885720 | Cyclic GMP specifically suppresses Type-Ialpha cGMP-dependent protein kinase expression by ubiquitination |
| Q34539833 | Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines. |
| Q41774906 | Cyclic guanosine monophosphate-dependent protein kinase I promotes adhesion of primary vascular smooth muscle cells. |
| Q34718342 | Cyclic nucleotide-dependent protein kinases inhibit binding of 14-3-3 to the GTPase-activating protein Rap1GAP2 in platelets. |
| Q37938771 | Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle. |
| Q37340786 | Cyclic nucleotide-regulated cation channels |
| Q40089868 | Cysteine redox sensor in PKGIa enables oxidant-induced activation |
| Q60678826 | Cysteine-Rich Protein 2, a Novel Downstream Effector of cGMP/cGMP-Dependent Protein Kinase I-Mediated Persistent Inflammatory Pain |
| Q36674615 | Cytoprotective signaling associated with nitric oxide upregulation in tumor cells subjected to photodynamic therapy-like oxidative stress |
| Q43235396 | Degradation of leucine zipper-positive isoform of MYPT1 may contribute to development of nitrate tolerance |
| Q54350699 | Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension. |
| Q41943788 | Dehydroepiandrosterone promotes pulmonary artery relaxation by NADPH oxidation-elicited subunit dimerization of protein kinase G 1α. |
| Q33635613 | Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin-proteasome systems |
| Q33989504 | Differential regulation of the foraging gene associated with task behaviors in harvester ants |
| Q40234554 | Dysregulation of cGMP-dependent protein kinase 1 (PKG-1) impairs erectile function in diabetic rats: influence of in vivo gene therapy of PKG1alpha |
| Q37692808 | Emerging gene and stem cell therapies for the treatment of erectile dysfunction |
| Q54301069 | Expression of cGMP-dependent protein kinase, PKGIα, PKGIβ, and PKGII in malignant and benign breast tumors. |
| Q37012737 | Expression, activity, and pro-hypertrophic effects of PDE5A in cardiac myocytes |
| Q27021649 | Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS |
| Q45929337 | Functional localization of the nitric oxide/cGMP pathway in the salamander retina. |
| Q52378670 | GCY-35/GCY-36-TAX-2/TAX-4 Signalling in O2 Sensory Neurons Mediates Acute Functional Ethanol Tolerance in Caenorhabditis elegans. |
| Q37346565 | Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1. |
| Q34592816 | Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells |
| Q38381894 | Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response |
| Q41767067 | Heparin responses in vascular smooth muscle cells involve cGMP-dependent protein kinase (PKG) |
| Q36638652 | High blood pressure arising from a defect in vascular function. |
| Q46216330 | Hydrogen peroxide induces dimerization of protein kinase G type Iα subunits and increases albumin permeability in cultured rat podocytes. |
| Q36808094 | Hypercontractility and impaired sildenafil relaxations in the BKCa channel deletion model of erectile dysfunction |
| Q35889176 | Hypoxic regulation of pulmonary vascular smooth muscle cyclic guanosine monophosphate-dependent kinase by the ubiquitin conjugating system |
| Q24304178 | IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation |
| Q33994665 | Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery |
| Q42940239 | Inhibition of inflammatory pain by activating B-type natriuretic peptide signal pathway in nociceptive sensory neurons. |
| Q41770411 | Insight into the rescue of oxidized soluble guanylate cyclase by the activator cinaciguat |
| Q47871041 | Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathway. |
| Q57248489 | Light-Driven Calcium Signals in Mouse Cone Photoreceptors |
| Q36766565 | MRP4-mediated regulation of intracellular cAMP and cGMP levels in trabecular meshwork cells and homeostasis of intraocular pressure |
| Q51246186 | Marked response to imatinib mesylate in a patient with platelet-derived growth factor receptor beta-associated acute myeloid leukemia. |
| Q37799652 | Modulating the nitric oxide - cyclic GMP pathway in the pressure-overloaded left ventricle and group II pulmonary hypertension. |
| Q52804250 | Molecular Analysis of Sensory Axon Branching Unraveled a cGMP-Dependent Signaling Cascade. |
| Q30487054 | Molecular basis for changes in behavioral state in ant social behaviors |
| Q37729120 | More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy. |
| Q27335893 | Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans |
| Q42094814 | Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. |
| Q38151237 | Myosin phosphatase isoforms as determinants of smooth muscle contractile function and calcium sensitivity of force production |
| Q37160515 | NMDA receptor activation increases free radical production through nitric oxide and NOX2. |
| Q33578042 | NO mediates microglial response to acute spinal cord injury under ATP control in vivo |
| Q24656131 | NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential |
| Q35928901 | Natural polymorphism affecting learning and memory in Drosophila |
| Q42000861 | Natural variation in Drosophila larval reward learning and memory due to a cGMP-dependent protein kinase. |
| Q34062825 | Neural programming of mesenteric and renal arteries |
| Q35033344 | Neuronal nitric oxide contributes to neuroplasticity-associated protein expression through cGMP, protein kinase G, and extracellular signal-regulated kinase |
| Q58863636 | Nitric Oxide, Oxidative Stress, Immune Response and Critical Care |
| Q34612428 | Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells |
| Q38844413 | Nitric oxide regulates antagonistically phagocytic and neurite outgrowth inhibiting capacities of microglia |
| Q35195095 | Nitric oxide signalling pathway in Duchenne muscular dystrophy mice: up-regulation of L-arginine transporters |
| Q39962813 | Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. |
| Q35596709 | Nitric oxide-cyclic GMP signaling in stem cell differentiation |
| Q24656438 | Nitric oxide-induced biphasic mechanism of vascular relaxation via dephosphorylation of CPI-17 and MYPT1 |
| Q37927098 | Nitric oxide: orchestrator of endothelium-dependent responses |
| Q26765793 | Novel Perspectives in Redox Biology and Pathophysiology of Failing Myocytes: Modulation of the Intramyocardial Redox Milieu for Therapeutic Interventions-A Review Article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology |
| Q24323077 | Novel crosstalk to BMP signalling: cGMP-dependent kinase I modulates BMP receptor and Smad activity |
| Q43004748 | Novel role for protein kinase g oxidative activation in the vasodilator and antihypertensive actions of hydrogen sulfide |
| Q27340411 | Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex |
| Q35964483 | Overexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury |
| Q34154543 | Oxidant-induced activation of cGMP-dependent protein kinase Iα mediates neuropathic pain after peripheral nerve injury. |
| Q33872491 | PDE5 inhibitor efficacy is estrogen dependent in female heart disease |
| Q36532454 | Pathophysiology of hypertension in the absence of nitric oxide/cyclic GMP signaling |
| Q33764566 | Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity |
| Q34150566 | Phospholemman Ser69 phosphorylation contributes to sildenafil-induced cardioprotection against reperfusion injury. |
| Q57284825 | Pleiotropy of the Drosophila melanogaster foraging gene on larval feeding-related traits |
| Q36977280 | Preservation of cGMP-induced relaxation of pulmonary veins of fetal lambs exposed to chronic high altitude hypoxia: role of PKG and Rho kinase |
| Q39380481 | Presynaptic inhibition of nociceptive neurotransmission by somatosensory neuron-secreted suppressors |
| Q42485358 | Presynaptic nitric oxide/cGMP facilitates glutamate release via hyperpolarization-activated cyclic nucleotide-gated channels in the hippocampus |
| Q21563535 | Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity |
| Q92403193 | Protein Kinase G Is Involved in Acute but Not in Long-Term Regulation of Renin Secretion |
| Q49699560 | Protein Kinases Type II (PKG II) Combined with L-Arginine Significantly Ameliorated Xenograft Tumor Development: Is L-Arginine a Potential Alternative in PKG II Activation? |
| Q38199441 | Protein S-nitrosylation in preconditioning and postconditioning |
| Q34421211 | Protein kinase G I and heart failure: Shifting focus from vascular unloading to direct myocardial antiremodeling effects |
| Q36171316 | Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veins |
| Q41819469 | Protein kinase G-I deficiency induces pulmonary hypertension through Rho A/Rho kinase activation |
| Q35809104 | Rapid S-nitrosylation of actin by NO-generating donors and in inflammatory pain model mice. |
| Q28388989 | Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling |
| Q57372759 | Regulation of RGS2 and Second Messenger Signaling in Vascular Smooth Muscle Cells by cGMP-dependent Protein Kinase |
| Q37960090 | Regulation of cardiovascular TRP channel functions along the NO-cGMP-PKG axis |
| Q38177693 | Regulation of endothelial nitric oxide synthase and high-density lipoprotein quality by estradiol in cardiovascular pathology |
| Q37801516 | Regulation of the pulmonary circulation in the fetus and newborn |
| Q28594677 | Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice |
| Q34362144 | Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis |
| Q50069687 | Role of Endogenous Nitric Oxide in Hyperaggressiveness of Tumor Cells that Survive a Photodynamic Therapy Challenge. |
| Q38962889 | Role of Protein Kinase G and Reactive Oxygen Species in the Regulation of Podocyte Function in Health and Disease |
| Q46628245 | Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia |
| Q36456848 | Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteries |
| Q37811990 | Role of nitric oxide in cerebellar development and function: focus on granule neurons |
| Q37093715 | Roles for cytosolic NADPH redox in regulating pulmonary artery relaxation by thiol oxidation-elicited subunit dimerization of protein kinase G1α |
| Q34144673 | Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis. |
| Q52589288 | Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. |
| Q54619325 | Signaling via IRAG is essential for NO/cGMP-dependent inhibition of platelet activation. |
| Q41031903 | Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy |
| Q36887547 | Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface |
| Q35075847 | Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension |
| Q42505728 | Species differences in the localization of soluble guanylyl cyclase subunits in monkey and rat brain. |
| Q44103267 | Structural Basis of Analog Specificity in PKG I and II. |
| Q36674623 | Structural Basis of Cyclic Nucleotide Selectivity in cGMP-dependent Protein Kinase II |
| Q36818087 | Structures of cGMP-Dependent Protein Kinase (PKG) Iα Leucine Zippers Reveal an Interchain Disulfide Bond Important for Dimer Stability |
| Q28279612 | Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease |
| Q47431700 | Switching Cyclic Nucleotide-Selective Activation of Cyclic Adenosine Monophosphate-Dependent Protein Kinase Holoenzyme Reveals Distinct Roles of Tandem Cyclic Nucleotide-Binding Domains |
| Q37089726 | Tackling heart failure in the twenty-first century |
| Q50280904 | The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord. |
| Q27321293 | The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity |
| Q33559599 | The Rho/Rac exchange factor Vav2 controls nitric oxide-dependent responses in mouse vascular smooth muscle cells. |
| Q36738013 | The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes |
| Q56700965 | The beta-3 adrenoceptor agonist, mirabegron relaxes isolated prostate from human and rabbit: New therapeutic indication? |
| Q92814978 | The cGMP Pathway and Inherited Photoreceptor Degeneration: Targets, Compounds, and Biomarkers |
| Q27024279 | The cGMP signaling pathway as a therapeutic target in heart failure with preserved ejection fraction |
| Q49740505 | The constitutively active PKG II mutant effectively inhibits gastric cancer development via a blockade of EGF/EGFR-associated signalling cascades. |
| Q47071411 | The foraging gene of Drosophila melanogaster: spatial-expression analysis and sucrose responsiveness |
| Q40150922 | The hinge region operates as a stability switch in cGMP-dependent protein kinase I alpha. |
| Q38123487 | The leech nervous system: a valuable model to study the microglia involvement in regenerative processes. |
| Q39192647 | The locust foraging gene. |
| Q33580106 | The nitric oxide-cGKII system relays death and survival signals during embryonic retinal development via AKT-induced CREB1 activation |
| Q28481326 | The nitric oxide-cyclic GMP pathway regulates FoxO and alters dopaminergic neuron survival in Drosophila |
| Q36619777 | The oligopeptide DT-2 is a specific PKG I inhibitor only in vitro, not in living cells |
| Q36119604 | The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord. |
| Q42138911 | The tumor suppressor p53 transcriptionally regulates cGKI expression during neuronal maturation and is required for cGMP-dependent growth cone collapse |
| Q36126228 | The visual orientation memory of Drosophila requires Foraging (PKG) upstream of Ignorant (RSK2) in ring neurons of the central complex |
| Q30436817 | Thromboxane A2-induced bi-directional regulation of cerebral arterial tone |
| Q36529020 | Transcriptional and post-transcriptional regulation of cGMP-dependent protein kinase (PKG-I): pathophysiological significance |
| Q39754573 | Transcriptional regulation of cGMP-dependent protein kinase II (cGK-II) in chondrocytes |
| Q90345460 | Transcriptomic Study of Porcine Small Intestine Epithelial Cells Reveals Important Genes and Pathways Associated With Susceptibility to Escherichia coli F4ac Diarrhea |
| Q57495849 | Treatment Selection in Pulmonary Arterial Hypertension: Phosphodiesterase Type 5 Inhibitors versus Soluble Guanylate Cyclase Stimulator |
| Q39484972 | Truncated IRAG variants modulate cGMP-mediated inhibition of human colonic smooth muscle cell contraction |
| Q38853266 | Two pathways of rod photoreceptor cell death induced by elevated cGMP. |
| Q39353975 | Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa |
| Q92737874 | Upregulation of Connexin 40 Mediated by Nitric Oxide Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage via the Nitric Oxide-Cyclic Guanosine Monophosphate-Protein Kinase G Pathway |
| Q46840707 | Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy |
| Q34432730 | Vascular smooth muscle phenotypic diversity and function |
| Q33321834 | Visual pattern memory requires foraging function in the central complex of Drosophila |
| Q26766587 | Why is nitric oxide important for our brain? |
| Q41870304 | [EXPRESS] Cyclic GMP-dependent protein kinase-I localized in nociceptors modulates nociceptive cortical neuronal activity and pain hypersensitivity |
| Q52578398 | cGMP Signaling and Vascular Smooth Muscle Cell Plasticity. |
| Q37165487 | cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function |
| Q50431784 | cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. |
| Q33418301 | cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis |
| Q51041188 | cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery. |
| Q27438117 | cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness |
| Q37855854 | cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment |
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