Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic

scientific article published on 12 October 2009

Transcriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TOX.2009.10.004
P698PubMed publication ID19822182

P50authorMichael P. WaalkesQ113460555
P2093author name stringHongzu Ren
J Christopher Corton
Don A Delker
Kirk T Kitchin
James W Allen
Bhalchandra A Diwan
Gail M Nelson
Gene J Ahlborn
Geremy Knapp
P2860cites workArsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancerQ23923854
The molecular mechanisms of arsenic-induced cell transformation and apoptosisQ24812452
Assessing susceptibility from early-life exposure to carcinogensQ24815464
Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposureQ25256866
Mechanisms of arsenic carcinogenicity: genetic or epigenetic mechanisms?Q26345064
Cancer chemoprevention by ginseng in mouse liver and other organsQ28366721
Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemiaQ28370464
Increased childhood liver cancer mortality and arsenic in drinking water in northern ChileQ28389177
Increased mortality from lung cancer and bronchiectasis in young adults after exposure to arsenic in utero and in early childhoodQ28390288
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXRQ28513664
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and ratsQ28578674
ATP-citrate lyase links cellular metabolism to histone acetylationQ29615367
Inorganic arsenic exposure and its relation to metabolic syndrome in an industrial area of TaiwanQ80270327
S-adenosyl-L-methionine counteracts mitotic disturbances and cytostatic effects induced by sodium arsenite in HeLa cellsQ81338228
Evaluation of the role of peroxisome proliferator-activated receptor alpha (PPARalpha) in mouse liver tumor induction by trichloroethylene and metabolitesQ82095301
Histone acetylation and cancerQ33632377
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver.Q33694520
Critical windows of exposure for children's health: cancer in human epidemiological studies and neoplasms in experimental animal modelsQ33942505
Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolitesQ33943279
Loss of stearoyl-CoA desaturase-1 function protects mice against adiposityQ33960868
Pharmacokinetics, metabolism, and carcinogenicity of arsenicQ34236890
Identification of potential caloric restriction mimetics by microarray profilingQ34454584
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effectsQ34581717
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patientsQ34739789
Evidence that arsenite acts as a cocarcinogen in skin cancerQ35846851
Use of arsenic trioxide in haematological malignancies: insight into the clinical development of a novel agentQ36089482
Peroxisome proliferator-activated receptor gamma coactivator 1 in caloric restriction and other models of longevityQ36372954
Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H miceQ36393258
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesisQ36557194
Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitusQ36971092
Liver diseases and metabolic syndromeQ37224466
Sodium arsenite accelerates TRAIL-mediated apoptosis in melanoma cells through upregulation of TRAIL-R1/R2 surface levels and downregulation of cFLIP expression.Q40214713
Ionizing radiation activates expression of FOXO3a, Fas ligand, and Bim, and induces cell apoptosisQ40251813
Extracts of Rehmanniae radix, Ginseng radix and Scutellariae radix improve glucose-stimulated insulin secretion and beta-cell proliferation through IRS2 inductionQ40734941
Genetics of liver tumor susceptibility in mice.Q40967225
Regulation of the expression of lipogenic enzyme genes by carbohydrateQ41548602
Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistanceQ42506602
Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocationQ43003956
Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in miceQ44313185
Global alteration of gene expression in human keratinocytes by inorganic arsenicQ44427338
Induction of tumors of the liver, lung, ovary and adrenal in adult mice after brief maternal gestational exposure to inorganic arsenic: promotional effects of postnatal phorbol ester exposure on hepatic and pulmonary, but not dermal cancersQ44599839
Induction of structural and numerical changes of chromosome, centrosome abnormality, multipolar spindles and multipolar division in cultured Chinese hamster V79 cells by exposure to a trivalent dimethylarsenic compound.Q44620655
Aneuploidy acts both oncogenically and as a tumor suppressorQ44738012
Dual effects of glutathione-S-transferase pi on As2O3 action in prostate cancer cells: enhancement of growth inhibition and inhibition of apoptosisQ44790857
Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesisQ44836543
Animal models for arsenic carcinogenesis: inorganic arsenic is a transplacental carcinogen in miceQ44994681
Some drinking-water disinfectants and contaminants, including arsenic. Monographs on chloramine, chloral and chloral hydrate, dichloroacetic acid, trichloroacetic acid and 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanoneQ45220833
Use of microarray biomarkers to identify longevity therapeuticsQ46101205
Co-ordinate activation of lipogenic enzymes in hepatocellular carcinomaQ46470997
Mouse skin tumor promotion by sodium arsenate is associated with enhanced PCNA expressionQ46487303
Vitamin E and organoselenium prevent the cocarcinogenic activity of arsenite with solar UVR in mouse skinQ46598627
The role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice: tumor-promoting action through the induction of oxidative stress.Q46614897
Case-control study of bladder cancer and arsenic in drinking waterQ46809950
Urogenital carcinogenesis in female CD1 mice induced by in utero arsenic exposure is exacerbated by postnatal diethylstilbestrol treatmentQ46923177
Exposure to arsenic at levels found inU.S. drinking water modifies expression in the mouse lung.Q50941383
Fifty-year study of lung and bladder cancer mortality in Chile related to arsenic in drinking water.Q50981303
Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis.Q51665999
Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice.Q53408366
Suppression of lung and liver carcinogenesis in mice by oral administration of myo-inositol.Q53415046
Opposing effects of arsenic trioxide on hepatocellular carcinomas in miceQ63859562
P433issue1-3
P407language of work or nameEnglishQ1860
P304page(s)6-15
P577publication date2009-10-12
P1433published inToxicologyQ1666328
P1476titleTranscriptional changes associated with reduced spontaneous liver tumor incidence in mice chronically exposed to high dose arsenic
P478volume266

Reverse relations

cites work (P2860)
Q64945501Aberrant lipid metabolism as a therapeutic target in liver cancer.
Q24707869Carcinogenic Effects of “Whole-Life” Exposure to Inorganic Arsenic in CD1 Mice
Q36083539Developmental exposure to 50 parts-per-billion arsenic influences histone modifications and associated epigenetic machinery in a region- and sex-specific manner in the adult mouse brain
Q34371580Evaluation of the carcinogenicity of inorganic arsenic
Q26799414In utero arsenic exposure in mice and early life susceptibility to cancer
Q37769295Oxygenomics in environmental stress.

Search more.