Characterization of [(3)H]-CGP54626A binding to heterodimeric GABA(B) receptors stably expressed in mammalian cells

scientific article published in December 2000

Characterization of [(3)H]-CGP54626A binding to heterodimeric GABA(B) receptors stably expressed in mammalian cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SJ.BJP.0703755
P8608Fatcat IDrelease_2lq4eksvuzebjbs4lzkvzy6wdq
P932PMC publication ID1572513
P698PubMed publication ID11139457
P5875ResearchGate publication ID12190677

P2093author name stringF H Marshall
A Green
R H Green
A Wise
A K Martin
S Walls
P2860cites workHeterodimerization is required for the formation of a functional GABA(B) receptorQ22008591
Molecular identification of the human GABABR2: cell surface expression and coupling to adenylyl cyclase in the absence of GABABR1Q22010017
Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptorsQ24308093
Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slicesQ24673400
Measurement of protein using bicinchoninic acidQ26778491
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionQ27860958
Distribution of the GABA(B) receptor subunit gb2 in rat CNSQ28139311
Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunitQ28371791
Evidence for pharmacologically distinct GABAB receptors associated with cAMP production in rat brainQ28567308
Cloning and tissue distribution of novel splice variants of the rat GABAB receptorQ31942020
GABAB receptors - the first 7TM heterodimers.Q33739386
gamma-aminobutyric acid(B) receptors: first of the functional metabotropic heterodimers.Q33799501
Calcium sensing properties of the GABA(B) receptor.Q33882738
3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brainQ34252242
GABA(B)-receptor subtypes assemble into functional heteromeric complexes.Q34485514
Pharmacologically distinct GABAB receptors that mediate inhibition of GABA and glutamate release in human neocortexQ35025328
Functional pharmacology of cloned heterodimeric GABAB receptors expressed in mammalian cellsQ35041724
G(o) transduces GABAB-receptor modulation of N-type calcium channels in cultured dorsal root ganglion neuronsQ36762829
GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G(0): antisense oligonucleotide studiesQ38315479
GABA(B) receptor isoforms GBR1a and GBR1b, appear to be associated with pre- and post-synaptic elements respectively in rat and human cerebellumQ38325448
Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand bindingQ40957427
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.Q40984747
Characterization of [3H]‐prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virusQ41851208
Differential effect of sodium ions and guanine nucleotides on the binding of thioperamide and clobenpropit to histamine H3-receptors in rat cerebral cortical membranesQ41919210
The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding.Q42058308
Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curvesQ42596115
Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranesQ42635308
Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein.Q42637004
Structural Basis for a Ca 2+ -Sensing Function of the Metabotropic Glutamate ReceptorsQ48502572
Domains determining ligand specificity for Ca2+ receptors.Q48921496
GABA(B) auto- versus hetero-receptor sensitivity: implications for novel pharmacotherapyQ73247323
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)1766-1774
P577publication date2000-12-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleCharacterization of [(3)H]-CGP54626A binding to heterodimeric GABA(B) receptors stably expressed in mammalian cells
P478volume131

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cites work (P2860)
Q34224641Advances in the molecular understanding of GABA(B) receptors.
Q40029292Direct detection of the interaction between recombinant soluble extracellular regions in the heterodimeric metabotropic gamma-aminobutyric acid receptor
Q33889093Discovery of a Negative Allosteric Modulator of GABAB Receptors
Q39993061Functional expression of GABAB receptors in airway epithelium
Q36820569GABA(B) receptors: structure and function
Q43826491Gabapentin is not a GABAB receptor agonist
Q33410720Identification of a membrane estrogen receptor in zebrafish with homology to mammalian GPER and its high expression in early germ cells of the testis.
Q35994557Identifying the role of pre-and postsynaptic GABA(B) receptors in behavior
Q41001603KCTD12 modulation of GABA(B) receptor function.
Q40660841Pharmacological characterisation of a cell line expressing GABA B1b and GABA B2 receptor subunits
Q42443418Positive regulation of GABA(B) receptors dually coupled to cyclic AMP by the allosteric agent CGP7930.
Q28573224The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABA(B) receptor activation
Q44194866Ventral tegmental area region governs GABA(B) receptor modulation of ethanol-stimulated activity in mice.

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