human | Q5 |
P496 | ORCID iD | 0000-0003-0566-2209 |
P3829 | Publons author ID | 1202618 |
P1053 | ResearcherID | C-3716-2009 |
P1153 | Scopus author ID | 7102355745 |
P166 | award received | Burton Medal | Q67856316 |
P69 | educated at | University of Cambridge | Q35794 |
P108 | employer | University of Toronto | Q180865 |
Hospital for Sick Children | Q3140964 | ||
Laboratory of Molecular Biology | Q185800 | ||
P735 | given name | John | Q4925477 |
John | Q4925477 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q41618089 | A Bayesian method for 3D macromolecular structure inference using class average images from single particle electron microscopy. |
Q92513029 | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery |
Q45175405 | ATP synthase from Saccharomyces cerevisiae: location of subunit h in the peripheral stalk region. |
Q44121908 | ATP synthase from Saccharomyces cerevisiae: location of the OSCP subunit in the peripheral stalk region |
Q36316024 | Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference |
Q24336527 | Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase |
Q35752572 | Alignment of cryo-EM movies of individual particles by optimization of image translations. |
Q46755670 | Angle determination for side views in single particle electron microscopy |
Q36122751 | Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM. |
Q41623560 | Assembly and structural analysis of a covalently closed nano-scale DNA cage. |
Q48121103 | Atomic model for the dimeric FO region of mitochondrial ATP synthase. |
Q45045809 | Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase |
Q40879471 | Automated particle picking for low-contrast macromolecules in cryo-electron microscopy |
Q41599182 | Cryo-EM Captures the Dynamics of Ion Channel Opening. |
Q27934094 | Cryo-EM structure of the yeast ATP synthase. |
Q26741088 | Cryo-EM studies of the structure and dynamics of vacuolar-type ATPases |
Q35667507 | Description and comparison of algorithms for correcting anisotropic magnification in cryo-EM images |
Q41615360 | Edged watershed segmentation: a semi-interactive algorithm for segmentation of low-resolution maps from electron cryomicroscopy. |
Q27700838 | Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase |
Q30392211 | Electron cryomicroscopy of membrane proteins: specimen preparation for two-dimensional crystals and single particles. |
Q99557908 | Electron-event representation data enable efficient cryoEM file storage with full preservation of spatial and temporal resolution |
Q87334388 | Enzyme mechanisms: Flexibility leads to function |
Q38186369 | Eukaryotic V-ATPase: novel structural findings and functional insights |
Q35051835 | Fabrication of carbon films with ∼ 500nm holes for cryo-EM with a direct detector device. |
Q91011234 | Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response |
Q27931718 | Location of subunit d in the peripheral stalk of the ATP synthase from Saccharomyces cerevisiae. |
Q27316939 | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance |
Q91291813 | Multiple conformations facilitate PilT function in the type IV pilus |
Q112583033 | Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers |
Q42660603 | Phospholipid association is essential for dynamin-related protein Mgm1 to function in mitochondrial membrane fusion. |
Q33851179 | Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents |
Q33708278 | Radiation damage in electron cryomicroscopy. |
Q91633300 | Shake-it-off: a simple ultrasonic cryo-EM specimen-preparation device |
Q27702091 | Structural Insights into KCTD Protein Assembly and Cullin3 Recognition |
Q31105909 | Structural analysis of membrane protein complexes by single particle electron microscopy. |
Q87525489 | Structural biology. Beyond blob-ology |
Q103743351 | Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11 |
Q34496933 | Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. |
Q90281594 | Structure of V-ATPase from the mammalian brain |
Q41598312 | Structure of a AAA+ unfoldase in the process of unfolding substrate. |
Q61798639 | Structure of a bacterial ATP synthase |
Q90288340 | Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis |
Q30493231 | Structure of intact Thermus thermophilus V-ATPase by cryo-EM reveals organization of the membrane-bound V(O) motor. |
Q39321223 | Structure of the Pseudomonas aeruginosa Type IVa Pilus Secretin at 7.4 Å. |
Q24633936 | Structure of the mitochondrial ATP synthase by electron cryomicroscopy |
Q41792129 | Structure of the vacuolar-type ATPase from Saccharomyces cerevisiae at 11-Å resolution |
Q27676276 | Subnanometre-resolution structure of the intact Thermus thermophilus H+-driven ATP synthase |
Q41611638 | TMaCS: A hybrid template matching and classification system for partially-automated particle selection |
Q39973916 | TROSY-based NMR evidence for a novel class of 20S proteasome inhibitors |
Q27675740 | The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2* |
Q42136906 | The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage. |
Q27658088 | The crystal structure of bacteriophage HK97 gp6: defining a large family of head-tail connector proteins |
Q90937273 | The human coronavirus HCoV-229E S-protein structure and receptor binding |
Q42152394 | The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture |
Q41619879 | The resolution dependence of optimal exposures in liquid nitrogen temperature electron cryomicroscopy of catalase crystals. |
Q27722410 | The structural basis of modified nucleosome recognition by 53BP1 |
Q38263285 | The study of vacuolar-type ATPases by single particle electron microscopy |
Q101150110 | Through-grid wicking enables high-speed cryoEM specimen preparation |
Q34027984 | Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy |
Q43276648 | Triggered instability of liposomes bound to hydrophobically modified core-shell PNIPAM hydrogel beads |
Q30789737 | Unfolding the mechanism of the AAA+ unfoldase VAT by a combined cryo-EM, solution NMR study |
Q26775536 | Validating maps from single particle electron cryomicroscopy |
Q55068997 | Vma9p need not be associated with the yeast V-ATPase for fully-coupled proton pumping activity in vitro. |
Q27322883 | YphC and YsxC GTPases assist the maturation of the central protuberance, GTPase associated region and functional core of the 50S ribosomal subunit |
Q30398255 | cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination |
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