Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors

scientific article published in October 2000

Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0960-894X(00)00430-3
P698PubMed publication ID11012026

P2093author name stringHofmann HP
Möller A
Lubisch W
Treiber HJ
P2860cites workStructure and physiological function of calpainsQ24530607
Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in ratsQ36895149
Cell-penetrating inhibitors of calpainQ37260529
Calpain inhibition: an overview of its therapeutic potentialQ40592886
Exploration of the importance of the P2-P3-NHCO-moiety in a potent di- or tripeptide inhibitor of calpain I: insights into the development of nonpeptidic inhibitors of calpain I.Q41033620
Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteasesQ42553698
Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical InhibitorsaQ47671491
A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsyQ48284517
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2AQ57398233
Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsinsQ70250641
Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpainQ72153804
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteasesQ72579390
P2-proline-derived inhibitors of calpain IQ77749430
P433issue19
P407language of work or nameEnglishQ1860
P1104number of pages5
P304page(s)2187-2191
P577publication date2000-10-01
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleSynthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors
P478volume10

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cites work (P2860)
Q47135149Antiepileptic and Neuroprotective Effects of Oleamide in Rat Striatum on Kainate-Induced Behavioral Seizure and Excitotoxic Damage via Calpain Inhibition
Q39661641Calpain inhibitors reduce retinal hypoxia in ischemic retinopathy by improving neovascular architecture and functional perfusion
Q37857282Calpain inhibitors: a survey of compounds reported in the patent and scientific literature
Q43981452Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors
Q45256092Distinct mechanistic roles of calpain and caspase activation in neurodegeneration as revealed in mice overexpressing their specific inhibitors.
Q35076795Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response
Q44011778Exploration of peptidyl hydrazones as water-soluble calpain inhibitors
Q37812402Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation
Q34754642Recent advances in the synthesis, design and selection of cysteine protease inhibitors

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