Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors

scientific article

Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-894X(02)00176-2
P698PubMed publication ID11992771
P5875ResearchGate publication ID11377256

P2093author name stringMöller A
Lubisch W
P2860cites workStructure and physiological function of calpainsQ24530607
A survey of calpain inhibitorsQ34060656
Increased calpain expression in activated glial and inflammatory cells in experimental allergic encephalomyelitisQ36098873
Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in ratsQ36895149
Cell-penetrating inhibitors of calpainQ37260529
Calpain inhibition: an overview of its therapeutic potentialQ40592886
Development and therapeutic potential of calpain inhibitorsQ41188037
Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitorsQ43507699
Calpain inhibitor-1 reduces infarct size and DNA fragmentation of myocardium in ischemic/reperfused rat heartQ47266495
Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical InhibitorsaQ47671491
Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene familyQ47833815
Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IκBα/NF-κB pathway in limb-girdle muscular dystrophy type 2AQ57398233
Alpha-diketone and alpha-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinasesQ68694270
Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpainQ72153804
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteasesQ72579390
Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administrationQ72841786
MDL-28170, a membrane-permeant calpain inhibitor, attenuates stunning and PKC epsilon proteolysis in reperfused ferret heartsQ73709614
P2-achiral, P'-extended alpha-ketoamide inhibitors of calpain IQ78222265
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectL-alanineQ218642
P1104number of pages4
P304page(s)1335-1338
P577publication date2002-05-01
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleDiscovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors
P478volume12

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cites work (P2860)
Q30320598Calpain inhibitor (BSF 409425) diminishes ischemia/reperfusion-induced damage of rabbit heart mitochondria
Q37857282Calpain inhibitors: a survey of compounds reported in the patent and scientific literature
Q76377719Energetic depression caused by mitochondrial dysfunction
Q33920306Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
Q37812402Physiologic and pathophysiologic role of calpain: implications for the occurrence of atrial fibrillation

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