The endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor

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The endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1164/RCCM.201301-0132OC
P698PubMed publication ID23795584

P50authorChun-Hua WangQ55416323
P2093author name stringChien-Da Huang
Chien-Huang Lin
Han-Pin Kuo
Bing-Chang Chen
Po-Hao Feng
Chih-Ming Weng
Meng-Jung Lee
P2860cites workConnective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animalsQ24648246
Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis modelQ28142724
Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosisQ28275409
CCN2 is required for bleomycin‐induced skin fibrosis in miceQ28295283
The role of fibrocytes in fibrotic diseases of the lungs and heartQ30433418
Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosisQ30435304
Tissue fibrocytes in patients with mild asthma: a possible link to thickness of reticular basement membrane?Q33237943
Airway remodeling and persistent airway obstruction in asthmaQ33731149
The role of endothelin-1 in the pathogenesis of idiopathic pulmonary fibrosisQ33792303
A novel single-chain-Fv antibody against connective tissue growth factor attenuates bleomycin-induced pulmonary fibrosis in miceQ33803330
Fibrosis and airway remodellingQ33940586
CCN2 is required for the TGF-β induced activation of Smad1-Erk1/2 signaling networkQ33961583
Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthmaQ34207374
The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses.Q34645189
Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy?Q34976913
CCN proteins: multifunctional signalling regulatorsQ35629272
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosisQ36849123
Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in sclerodermaQ37093118
The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosisQ37415507
Connective tissue growth factor (CTGF/CCN2) ELISA: a novel tool for monitoring fibrosisQ37877254
Endothelin-1, via ETA receptor and independently of transforming growth factor-beta, increases the connective tissue growth factor in vascular smooth muscle cells.Q38324521
Neutrophil elastase represses IL-8/CXCL8 synthesis in human airway smooth muscle cells through induction of NF-kappa B repressing factorQ39835357
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.Q40902696
The endothelins in the pulmonary systemQ40943388
The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblastsQ41766529
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK.Q42459183
Tissue factor-thrombin signaling enhances the fibrotic activity of myofibroblasts in systemic sclerosis through up-regulation of endothelin receptor A.Q42492897
Severe fibrosis and increased expression of fibrogenic cytokines in the gastric wall of systemic sclerosis patientsQ42519579
ETA and ETB receptors are expressed in vascular adventitial fibroblasts.Q44688640
Increased TGF-beta2 in severe asthma with eosinophiliaQ45215090
Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.Q46873529
Endothelin-1 levels in the pathophysiology of chronic obstructive pulmonary disease and bronchial asthmaQ48621083
Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.Q54530522
CCN2 is necessary for the function of mouse embryonic fibroblasts.Q54561247
Expression of connective tissue growth factor in asthmatic airway smooth muscle cells.Q54798238
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectconnective tissueQ25615
asthmaQ35869
P304page(s)298-308
P577publication date2013-08-01
P1433published inAmerican Journal of Respiratory and Critical Care MedicineQ4744267
P1476titleThe endothelin A receptor mediates fibrocyte differentiation in chronic obstructive asthma. The involvement of connective tissue growth factor
P478volume188

Reverse relations

cites work (P2860)
Q34046726CXCL12 induces connective tissue growth factor expression in human lung fibroblasts through the Rac1/ERK, JNK, and AP-1 pathways
Q39397633Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity
Q36324128Effects of IFN-γ on cell growth and the expression of ADAM33 gene in human embryonic lung Mrc-5 fibroblasts in vitro
Q35668241Endothelin Receptors Expressed by Immune Cells Are Involved in Modulation of Inflammation and in Fibrosis: Relevance to the Pathogenesis of Systemic Sclerosis.
Q35870325Enumeration of circulating fibrocytes for clinical use in asthma by an optimized single-platform flow cytometry assay.
Q58787537Fibroblast-to-myofibroblast transition in bronchial asthma
Q36093588Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways
Q38370676Involvement of fibrocytes in asthma and clinical implications
Q51418425MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts.
Q36070666Nitrative stress, oxidative stress and plasma endothelin levels after inhalation of particulate matter and ozone
Q38180825Paracrine functions of fibrocytes to promote lung fibrosis
Q37237979RPTOR, a novel target of miR-155, elicits a fibrotic phenotype of cystic fibrosis lung epithelium by upregulating CTGF.
Q36705598Role of Circulating Fibrocytes in Cardiac Fibrosis
Q33732168Update in asthma 2013
Q38794416miR-19a, -19b, and -26b Mediate CTGF Expression and Pulmonary Fibroblast Differentiation

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