Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis

scientific article

Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BIOCEL.2009.02.020
P932PMC publication ID2681415
P698PubMed publication ID19433312
P5875ResearchGate publication ID24418848

P50authorBorna MehradQ41554549
P2093author name stringMarie D Burdick
Robert M Strieter
P2860cites workMechanism of action and in vivo role of platelet-derived growth factorQ22010594
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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrixQ29619797
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Circulating peripheral blood fibrocytes in human fibrotic interstitial lung diseaseQ30442380
Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxiaQ33279493
CXCR4: chemokine receptor extraordinaireQ34118771
Morphometric analysis of insulin-like growth factor-I localization in lung tissues of patients with idiopathic pulmonary fibrosisQ77563810
Dual-immunohistochemistry provides little evidence for epithelial-mesenchymal transition in pulmonary fibrosisQ80597495
Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosisQ80977273
Gefitinib prevents bleomycin-induced lung fibrosis in miceQ83896403
mTOR inhibitors in the treatment of cancerQ94801373
Platelet-derived growth factor in idiopathic pulmonary fibrosisQ34261287
CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injuryQ34399563
HIV entry inhibitors.Q34654433
Bone marrow-derived progenitor cells in pulmonary fibrosisQ35022598
Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosisQ35080464
Insulin-like growth factor binding proteins 3 and 5 are overexpressed in idiopathic pulmonary fibrosis and contribute to extracellular matrix depositionQ35083605
Stromal derived factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasisQ35131138
Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltrationQ35607286
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouseQ35608869
Circulating fibrocytes: collagen-secreting cells of the peripheral bloodQ35686362
Essential roles of the CC chemokine ligand 3-CC chemokine receptor 5 axis in bleomycin-induced pulmonary fibrosis through regulation of macrophage and fibrocyte infiltration.Q35781428
Reduction of bleomycin-induced pulmonary fibrosis by serum amyloid P.Q35787045
Specific inhibitors of platelet-derived growth factor or epidermal growth factor receptor tyrosine kinase reduce pulmonary fibrosis in ratsQ35787237
CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironmentQ36306137
Regulation of the chemokine receptor CXCR4 by hypoxiaQ36371842
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.Q36403334
Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activityQ36563209
Mobilizing stem cells from normal donors: is it possible to improve upon G-CSF?Q36763610
Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte functionQ36822323
Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosisQ36849123
The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?Q36970923
Epithelial cell alpha3beta1 integrin links beta-catenin and Smad signaling to promote myofibroblast formation and pulmonary fibrosisQ37036076
Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilizationQ37306633
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cellsQ38311709
Haematologic Adaptation in Patients with Chronic Bronchitis and Pulmonary InsufficiencyQ39085649
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxQ40440548
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.Q40633683
OXYGEN SATURATION OF STERNAL MARROW BLOOD IN POLYCYTHEMIA VERA.Q40999810
Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomideQ41197059
Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor beta and relationship to disease severityQ41438692
Enhanced insulin-like growth factor molecules in idiopathic pulmonary fibrosisQ41665426
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrowQ41788910
The role of CCL12 in the recruitment of fibrocytes and lung fibrosis.Q42105688
The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastasesQ43671920
Exaggerated spontaneous release of platelet-derived growth factor by alveolar macrophages from patients with idiopathic pulmonary fibrosisQ43864575
The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.Q44056582
Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injuryQ47653534
Circulating Fibrocytes Are an Indicator of Poor Prognosis in Idiopathic Pulmonary FibrosisQ61892487
Peripheral blood fibrocytes: differentiation pathway and migration to wound sitesQ73966720
Oxygen saturation in the bone marrow of healthy volunteersQ77468027
P433issue8-9
P921main subjectpulmonary fibrosisQ32446
P304page(s)1708-1718
P577publication date2009-03-06
P1433published inInternational Journal of Biochemistry & Cell BiologyQ6051320
P1476titleFibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis
P478volume41

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