| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M500963200 |
| P698 | PubMed publication ID | 15802268 |
| P2093 | author name string | Marie D Burdick | |
| Robert M Strieter | |||
| Javier Mestas | |||
| John A Belperio | |||
| Antonio Sica | |||
| Michael P Keane | |||
| Mehrnaz Gharaee-Kermani | |||
| Roderick J Phillips | |||
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| P433 | issue | 23 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sirolimus | Q32089 |
| hypoxia | Q105688 | ||
| P304 | page(s) | 22473-22481 | |
| P577 | publication date | 2005-03-31 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypox | |
| P478 | volume | 280 |
| Q42415178 | 55th Bowditch Lecture: Effects of chronic hypoxia on the pulmonary circulation: role of HIF-1. |
| Q57107876 | A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells |
| Q37387466 | A novel variant of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells |
| Q35179502 | ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling |
| Q91666691 | Advancement in Stem Cell Therapy for Ischemic Myocardial Cell: A Systematic Review |
| Q35124198 | Alpha-fetoprotein activates AKT/mTOR signaling to promote CXCR4 expression and migration of hepatoma cells |
| Q39690717 | Androgens Induce Functional CXCR4 through ERG Factor Expression in TMPRSS2-ERG Fusion-Positive Prostate Cancer Cells |
| Q47111722 | Anti-proliferative and pro-apoptotic effects induced by simultaneous inactivation of HER1 and HER2 through endogenous polyclonal antibodies |
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| Q51269789 | C-X-C Chemokine Receptor Type 4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte Injury. |
| Q53162585 | CCR3 induced-p42/44 MAPK activation protects against staurosporine induced-DNA fragmentation but not apoptosis in airway smooth muscle cells. |
| Q33410331 | CXC chemokine receptor 4 expression, CXC chemokine receptor 4 activation, and wild-type nucleophosmin are independently associated with unfavorable prognosis in patients with acute myeloid leukemia |
| Q24635943 | CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression |
| Q40381071 | CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation |
| Q30439235 | CXCR4 expression on circulating pan-cytokeratin positive cells is associated with survival in patients with advanced non-small cell lung cancer |
| Q26781915 | CXCR4 in breast cancer: oncogenic role and therapeutic targeting |
| Q39868955 | CXCR4+FOXP3+CD25+ lymphocytes accumulate in CXCL12-expressing malignant pleural mesothelioma |
| Q30408881 | CXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cells |
| Q36583985 | CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential |
| Q27009526 | CXCR4/CXCL12 in non-small-cell lung cancer metastasis to the brain |
| Q33672265 | CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression |
| Q27860907 | Cancer-related inflammation |
| Q37187711 | Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice |
| Q37351199 | Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors |
| Q35138504 | Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors |
| Q36906094 | Chemokines and their receptors in lung cancer progression and metastasis |
| Q30435873 | Chemokines as therapeutic targets in renal cell carcinoma |
| Q37041249 | Clarifying CB2 receptor-dependent and independent effects of THC on human lung epithelial cells |
| Q36011854 | Clinicopathological and therapeutic significance of CXCL12 expression in lung cancer |
| Q35095399 | Coexpression of EGFR and CXCR4 predicts poor prognosis in resected pancreatic ductal adenocarcinoma |
| Q37204970 | Combined targeting of EGFR-dependent and VEGF-dependent pathways: rationale, preclinical studies and clinical applications |
| Q39931189 | Copper regulation of hypoxia-inducible factor-1 activity |
| Q35094456 | Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression |
| Q35129112 | CypA, a gene downstream of HIF-1α, promotes the development of PDAC |
| Q38015856 | Differential Expression of Chemokine Receptors and their Roles in Cancer Imaging. |
| Q36610138 | Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy. |
| Q34541713 | Dual inhibition of plasminogen kringle 5 on angiogenesis and chemotaxis suppresses tumor metastasis by targeting HIF-1α pathway |
| Q37701050 | EGFR expression is associated with cytoplasmic staining of CXCR4 and predicts poor prognosis in triple-negative breast carcinomas |
| Q34048283 | EGFR variant-mediated invasion by enhanced CXCR4 expression through transcriptional and post-translational mechanisms |
| Q36544904 | EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF. |
| Q38379360 | Effect of CXCL12/CXCR4 on increasing the metastatic potential of non-small cell lung cancer in vitro is inhibited through the downregulation of CXCR4 chemokine receptor expression |
| Q28252815 | Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis |
| Q36214623 | Efficacy and safety of the hypoxia-activated prodrug TH-302 in combination with gemcitabine and nab-paclitaxel in human tumor xenograft models of pancreatic cancer |
| Q34380220 | Elevated expression of CXC chemokines in pediatric osteosarcoma patients |
| Q36614997 | Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer |
| Q93196102 | Emerging role of PTEN loss in evasion of the immune response to tumours |
| Q37116246 | Emerging role of adipose tissue hypoxia in obesity and insulin resistance |
| Q33669174 | Enhanced interferon-gamma gene expression in T Cells and reduced ovalbumin-dependent lung eosinophilia in hypoxia-inducible factor-1-alpha-deficient mice |
| Q37723500 | Enhancing the efficacy of mesenchymal stem cell therapy |
| Q39663655 | Enzastaurin inhibits invasion and metastasis in lung cancer by diverse molecules |
| Q34575299 | Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer |
| Q39739616 | Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1alpha in non-small cell lung cancer cells |
| Q38986743 | Escin suppresses migration and invasion involving the alteration of CXCL16/CXCR6 axis in human gastric adenocarcinoma AGS cells |
| Q30435304 | Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis |
| Q37887074 | Fibrocytes and the tissue niche in lung repair |
| Q37175083 | G-protein coupled chemoattractant receptors and cancer |
| Q34606002 | G-protein-coupled receptors and cancer. |
| Q33814898 | Galectin-1 upregulates CXCR4 to promote tumor progression and poor outcome in kidney cancer |
| Q38518910 | Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes |
| Q36809751 | Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease |
| Q33943870 | Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis. |
| Q41678886 | HIF1α and metabolic reprogramming in inflammation. |
| Q36493913 | HIFing the brakes: therapeutic opportunities for treatment of human malignancies |
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| Q92713823 | High CXCR4 Expression Predicts a Poor Prognosis in Resected Lung Adenosquamous Carcinoma |
| Q51753083 | Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer. |
| Q21142766 | Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment |
| Q40002656 | Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). |
| Q28585802 | Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation |
| Q36831465 | Hypoxia-inducible factors and cancer. |
| Q28393898 | Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells |
| Q42876765 | Hypoxic preconditioning advances CXCR4 and CXCR7 expression by activating HIF-1α in MSCs |
| Q35578377 | IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis |
| Q37138676 | Identification of crucial microRNAs and genes in hypoxia-induced human lung adenocarcinoma cells |
| Q38876568 | Implications of Oxygen Homeostasis for Tumor Biology and Treatment. |
| Q42570987 | Importance of the SDF-1:CXCR4 axis in myocardial repair |
| Q38998235 | In vitro study of normoxic epidermal growth factor receptor-induced hypoxia-inducible factor-1-alpha, vascular endothelial growth factor, and BNIP3 expression in head and neck squamous cell carcinoma cell lines: Implications for anti-epidermal growt |
| Q35174944 | Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy |
| Q22252327 | Inflammation and cancer: The oncogene-driven connection |
| Q35874453 | Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells |
| Q36494138 | Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs |
| Q40211862 | Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase |
| Q90640831 | Interaction between CXCR4 and EGFR and downstream PI3K/AKT pathway in lung adenocarcinoma A549 cells and transplanted tumor in nude mice |
| Q40257917 | Involvement of HIF-1 in invasion of Mum2B uveal melanoma cells |
| Q36805595 | KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib |
| Q28388722 | Loss of PTEN permits CXCR4-mediated tumorigenesis through ERK1/2 in prostate cancer cells |
| Q51418425 | MEKK1, JNK, and SMAD3 mediate CXCL12-stimulated connective tissue growth factor expression in human lung fibroblasts. |
| Q36822184 | Manipulating the chemokine-chemokine receptor network to treat cancer |
| Q81171249 | Masters of angiogenesis |
| Q27003907 | Mechanisms driving macrophage diversity and specialization in distinct tumor microenvironments and parallelisms with other tissues |
| Q33377459 | Mechanisms underlying hypoxia tolerance in Drosophila melanogaster: hairy as a metabolic switch |
| Q34919916 | Melittin suppresses HIF-1α/VEGF expression through inhibition of ERK and mTOR/p70S6K pathway in human cervical carcinoma cells |
| Q36407511 | Metastasis: recent discoveries and novel treatment strategies |
| Q27320221 | Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1. |
| Q43140228 | Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors |
| Q33666145 | NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction |
| Q36488744 | New signals from the invasive front |
| Q34199098 | Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways |
| Q30438282 | Out of the shadows: CXC chemokines in promoting aberrant lung cancer angiogenesis |
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