Richard N. Fedorak

researcher ORCID ID = 0000-0002-7382-0080

Born 1955-05-28 in Edmonton (Q2096)
Died 2018-11-08

Richard N. Fedorak is …
instance of (P31):
humanQ5

External links are
P1960Google Scholar author IDNFr3YykAAAAJ
P213ISNI0000000137778535
P2941Munk's Roll IDrichard-neil-fedorak
P496ORCID iD0000-0002-7382-0080
P2038ResearchGate profile IDRichard_Fedorak
P1153Scopus author ID7005513192

P27country of citizenshipCanadaQ16
P108employerUniversity of AlbertaQ640694
P734family nameFedorakQ37436080
FedorakQ37436080
FedorakQ37436080
P101field of workgastroenterologyQ120569
P735given nameRichardQ1249148
RichardQ1249148
NeilQ5570878
NeilQ5570878
P463member ofRoyal Society of CanadaQ94301
Royal College of Physicians of EdinburghQ2170997
Canadian Academy of Health SciencesQ5029644
Royal College of Physicians, LondonQ16003969
P106occupationphysicianQ39631
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q36520699A 29-year-old woman with Crohn disease considering pregnancy
Q40069488A Systematic Review for the Development of a Core Outcome Set for Ulcerative Colitis Clinical Trials
Q52572938A defect in epithelial barrier integrity is not required for a systemic response to bacterial antigens or intestinal injury in T cell receptor-alpha gene-deficient mice.
Q39301057A machine-learned predictor of colonic polyps based on urinary metabolomics.
Q59120393A one-hour infusion of infliximab during maintenance therapy is safe and well tolerated: a prospective cohort study
Q35694889A randomized controlled trial of four precolonoscopy bowel cleansing regimens
Q56992312A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
Q33916760A randomized trial of topical anesthesia comparing lidocaine versus lidocaine plus xylometazoline for unsedated transnasal upper gastrointestinal endoscopy
Q28270722A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
Q59120756A randomized, placebo-controlled, double-blind trial of mesalamine in the maintenance of remission of Crohn's disease. The Canadian Mesalamine for Remission of Crohn's Disease Study Group
Q35100143A study investigating the association of dermatological and infusion reactions to infliximab and infliximab trough levels
Q59120887Acetic acid-induced colitis results in bystander ileal injury
Q59120396Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial
Q37240622Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial.
Q34654409Adalimumab for orbital myositis in a patient with Crohn's disease who discontinued infliximab: a case report and review of the literature
Q38184706Adalimumab versus infliximab for the treatment of moderate to severe ulcerative colitis in adult patients naïve to anti-TNF therapy: an indirect treatment comparison meta-analysis
Q46729988Allopurinol to prevent pancreatitis after endoscopic retrograde cholangiopancreatography: a randomized placebo-controlled trial
Q36881638American gastroenterological association consensus development conference on the use of biologics in the treatment of inflammatory bowel disease, June 21-23, 2006.
Q53333615An imbalance in mucosal cytokine profile causes transient intestinal inflammation following an animal's first exposure to faecal bacteria and antigens.
Q53196223Anti-TNF Therapy Within 2 Years of Crohn's Disease Diagnosis Improves Patient Outcomes: A Retrospective Cohort Study.
Q52564350Association with selected bacteria does not cause enterocolitis in IL-10 gene-deficient mice despite a systemic immune response.
Q59120486Bacterial antigens alone can influence intestinal barrier integrity, but live bacteria are required for initiation of intestinal inflammation and injury
Q55050753Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice.
Q59120553Bones and Crohnʼs
Q34565768Breaks in the wall: increased gaps in the intestinal epithelium of irritable bowel syndrome patients identified by confocal laser endomicroscopy (with videos).
Q59120828Budesonide‐β‐D‐glucuronide: A Potential Prodrug for Treatment of Ulcerative Colitis
Q53517484CD4+CD25+ regulatory T cells have divergent effects on intestinal inflammation in IL-10 gene-deficient mice.
Q35962097Canadian Digestive Health Foundation Public Impact Series 3: irritable bowel syndrome in Canada. Incidence, prevalence, and direct and indirect economic impact
Q34639486Canadian Digestive Health Foundation Public Impact Series 4: celiac disease in Canada. Incidence, prevalence, and direct and indirect economic impact
Q27023094Canadian Digestive Health Foundation Public Impact Series 5: Pancreatitis in Canada. Incidence, prevalence, and direct and indirect economic impact
Q34417015Canadian Digestive Health Foundation Public Impact Series. Inflammatory bowel disease in Canada: Incidence, prevalence, and direct and indirect economic impact
Q24633952Canadian Digestive Health Foundation Public Impact Series: gastroesophageal reflux disease in Canada: incidence, prevalence, and direct and indirect economic impact
Q59120308Celiac Disease in Children With Inflammatory Bowel Disease: a Prospective Cohort Study
Q42659842Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab
Q36428382Certolizumab pegol, a monthly subcutaneously administered Fc-free anti-TNFalpha, improves health-related quality of life in patients with moderate to severe Crohn's disease
Q38045701Challenges to the design, execution, and analysis of randomized controlled trials for inflammatory bowel disease
Q34585762Clinical experience with infliximab for Crohn's disease: the first 100 patients in Edmonton, Alberta
Q46196287Clinical trial: intravenous pantoprazole vs. ranitidine for the prevention of peptic ulcer rebleeding: a multicentre, multinational, randomized trial
Q46489074Colonic delivery of dexamethasone from a prodrug accelerates healing of colitis in rats without adrenal suppression
Q43512391Commentary: larazotide acetate - an exciting new development for coeliac patients? Authors' reply.
Q44769286Conservative approach to severe ulcerative colitis
Q36285782Crohn's disease genotypes of patients in remission vs relapses after infliximab discontinuation.
Q59120865Crypt cell production rate, enterocyte turnover time and appearance of transport along the jejunal villus of the rat
Q41867113Development and validation of a highly sensitive urine-based test to identify patients with colonic adenomatous polyps
Q36322290Development and validation of an administrative case definition for inflammatory bowel diseases
Q38672414Development of a core outcome set for clinical trials in inflammatory bowel disease: study protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey
Q33786052Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study.
Q59120452Differential clustering of bowel biopsy-associated bacterial profiles of specimens collected in Mexico and Canada: what do these profiles represent?
Q37516556Disease manifestations of Helicobacter pylori infection in Arctic Canada: using epidemiology to address community concerns
Q30486789Distance management of inflammatory bowel disease: systematic review and meta-analysis
Q35216619Does the level of reproductive knowledge specific to inflammatory bowel disease predict childlessness among women with inflammatory bowel disease?
Q35056003Don't Forget the Doctor: Gastroenterologists' Preferences on the Development of mHealth Tools for Inflammatory Bowel Disease
Q35624602Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity.
Q59120970Effect of misoprostol in preventing stress-induced intestinal fluid secretion in rats
Q37571701Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease
Q35995244Epithelial Cell Extrusion Zones Observed on Confocal Laser Endomicroscopy Correlates with Immunohistochemical Staining of Mucosal Biopsy Samples
Q52578345Epithelial barrier disruption allows nondisease-causing bacteria to initiate and sustain IBD in the IL-10 gene-deficient mouse.
Q50482700Epithelial cell extrusion leads to breaches in the intestinal epithelium.
Q34511748Epithelial gaps in a rodent model of inflammatory bowel disease: a quantitative validation study
Q52507776FK506 increases permeability in rat intestine by inhibiting mitochondrial function.
Q42704205HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
Q35452992Health care resource use and costs in Crohn's disease before and after infliximab therapy
Q53076589Heterogeneity in Definitions of Efficacy and Safety Endpoints for Clinical Trials of Crohn's Disease: A Systematic Review for Development of a Core Outcome Set.
Q28296771Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial
Q44690253Inadequate knowledge of immunization guidelines: a missed opportunity for preventing infection in immunocompromised IBD patients
Q34511806Increased epithelial gaps in the small intestine are predictive of hospitalization and surgery in patients with inflammatory bowel disease
Q33844058Increased epithelial gaps in the small intestines of patients with inflammatory bowel disease: density matters
Q59120792Increased permeability occurs in rat ileum following induction of pancolitis
Q36082156Inflammatory bowel disease patients are frequently nonadherent to scheduled induction and maintenance infliximab therapy: A Canadian cohort study.
Q28246982Infliximab maintenance therapy for fistulizing Crohn's disease
Q88930148Innovative Online Educational Portal Improves Disease-Specific Reproductive Knowledge Among Patients With Inflammatory Bowel Disease
Q59120799Insulin downregulates diabetic-enhanced intestinal glucose transport rapidly in ileum and slowly in jejunum
Q59120768Interleukin 10 prevents cytokine-induced disruption of T84 monolayer barrier integrity and limits chloride secretion
Q59120359Intravenous Injection of Endogenous Microbial Components Abrogates DSS-Induced Colitis
Q37992243Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis
Q35978793Is it time to re-classify Crohn's disease?
Q59120896Jejunum is preferable for construction of a bianchi bowel-lengthening procedure in swine short bowel
Q35670680Knowledge of Fecal Calprotectin and Infliximab Trough Levels Alters Clinical Decision-making for IBD Outpatients on Maintenance Infliximab Therapy.
Q59120602Lack of Interleukin-10 Leads to Intestinal Inflammation, Independent of the Time at Which Luminal Microbial Colonization Occurs
Q59120722Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease
Q59120727Lactobacillus species prevents colitis in interleukin 10 gene–deficient mice
Q35655989Larazotide acetate for persistent symptoms of celiac disease despite a gluten-free diet: a randomized controlled trial.
Q35216610Living with inflammatory bowel disease: A Crohn's and Colitis Canada survey
Q59120870Low-Dose Cyclosporine for the Treatment of Crohn's Disease
Q26776151Lymphoproliferative disorders in inflammatory bowel disease patients on immunosuppression: Lessons from other inflammatory disorders
Q51753771Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort.
Q36997228Metabolomic profiles are gender, disease and time specific in the interleukin-10 gene-deficient mouse model of inflammatory bowel disease
Q37797462Metabolomics and Detection of Colorectal Cancer in Humans: A Systematic Review
Q28646298Metagenomic analysis of microbiome in colon tissue from subjects with inflammatory bowel diseases reveals interplay of viruses and bacteria
Q59120846Methotrexate for the Treatment of Crohn's Disease
Q43531369Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease
Q33732599Mind the gaps: confocal endomicroscopy showed increased density of small bowel epithelial gaps in inflammatory bowel disease.
Q59120921Misoprostol therapy following trinitrobenzene sulfonic acid-induced colitis accelerates healing
Q37175815Molecular patterns in human ulcerative colitis and correlation with response to infliximab
Q59120927Mucosal protective effects of vitamin E and misoprostol during acute radiation-induced enteritis in rats
Q42037558Murine ileocolic bowel resection with primary anastomosis.
Q46688826Natalizumab for the treatment of active Crohn's disease: results of the ENCORE Trial
Q52598967Naturally occurring glycoalkaloids in potatoes aggravate intestinal inflammation in two mouse models of inflammatory bowel disease.
Q59120403Neonatal exposure to fecal antigens reduces intestinal inflammation
Q88376278Noninvasive Fecal Immunochemical Testing and Fecal Calprotectin Predict Mucosal Healing in Inflammatory Bowel Disease: A Prospective Cohort Study
Q59120632Normal Breast Milk Limits the Development of Colitis in IL-10–Deficient Mice
Q59120806Nutritional and intestinal effects of the novel immunosuppressive agents: Deoxyspergualin, rapamycin, and mycophenolate mofetil
Q59120493Onercept for Moderate-to-Severe Crohn’s Disease: A Randomized, Double-Blind, Placebo-Controlled Trial
Q45975206Oral administration of curcumin emulsified in carboxymethyl cellulose has a potent anti-inflammatory effect in the IL-10 gene-deficient mouse model of IBD.
Q41151384Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD.
Q35026236Oropharyngeal Crohn's disease
Q36091362Patients undergoing colorectal cancer screening underestimate their cancer risk and delay presentation for screening
Q51620685Patients with Active Luminal Crohn's Disease Have Evidence of Significant Functional and Clinical Pulmonary Involvement.
Q34287642Patients with inflammatory bowel disease exhibit dysregulated responses to microbial DNA
Q51820079Peptic ulcer bleeding outcomes adversely affected by end-stage renal disease.
Q44409876Phenotypic features of Crohn's disease associated with failure of medical treatment.
Q46068220Pneumococcal pneumonia: potential for diagnosis through a urinary metabolic profile.
Q36207261Postoperative Crohn's disease.
Q35959598Practical Considerations and the Intestinal Microbiome in Disease: Antibiotics for IBD Therapy.
Q34789021Predicting, treating and preventing postoperative recurrence of Crohn's disease: the state of the field
Q33629237Primary Outcomes From a Phase 3, Randomized, Double-Blind, Active-Controlled Trial of Surotomycin in Subjects With Clostridium difficile Infection
Q48677169Probiotic preparation VSL#3 induces remission in children with mild to moderate acute ulcerative colitis: a pilot study
Q36281405Probiotics and nutraceuticals: non-medicinal treatments of gastrointestinal diseases
Q36036491Probiotics and prebiotics in gastrointestinal disorders.
Q35854517Probiotics and the management of inflammatory bowel disease.
Q36348570Probiotics in the management of inflammatory bowel disease.
Q24630676Probiotics in the management of ulcerative colitis
Q36457614Probiotics in the treatment of inflammatory bowel disease.
Q34796336Prospective Study of the Quality of Colonoscopies Performed by Primary Care Physicians: The Alberta Primary Care Endoscopy (APC-Endo) Study
Q46607949Randomised clinical trial: vercirnon, an oral CCR9 antagonist, vs. placebo as induction therapy in active Crohn's disease
Q45259872Randomized trial of etidronate plus calcium and vitamin D for treatment of low bone mineral density in Crohn's disease
Q45841458Randomized, double-blind, placebo-controlled trial of the oral interleukin-12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease
Q37342575Real-Life Treatment Paradigms Show Adalimumab Is Cost-Effective for the Management of Ulcerative Colitis.
Q51745588Real-life treatment paradigms show infliximab is cost-effective for management of ulcerative colitis.
Q34012172Recommendations for probiotic use--2008.
Q40128492Recurrent Fevers After Infliximab Therapy for Ulcerative Colitis
Q38121115Review article: a clinician's guide for therapeutic drug monitoring of infliximab in inflammatory bowel disease.
Q33792368Review article: acid suppression in non-variceal acute upper gastrointestinal bleeding.
Q57218404Risedronate improves bone mineral density in Crohn's disease: a two year randomized controlled clinical trial
Q59120205Role of Vitamin D in Infliximab-induced Remission in Adult Patients with Crohnʼs Disease
Q39538749Similar Clinical and Surgical Outcomes Achieved with Early Compared to Late Anti-TNF Induction in Mild-to-Moderate Ulcerative Colitis: A Retrospective Cohort Study
Q53175432Small bowel fibrosis and systemic inflammatory response after ileocolonic anastomosis in IL-10 null mice.
Q59120814Small intestinal function following syngeneic transplantation in the rat.
Q45977890Steroid-sparing properties of sargramostim in patients with corticosteroid-dependent Crohn's disease: a randomised, double-blind, placebo-controlled, phase 2 study.
Q34524615Systematic review of stimulant and nonstimulant laxatives for the treatment of functional constipation
Q88478503Systematic review with meta-analysis: endoscopic and histologic placebo rates in induction and maintenance trials of ulcerative colitis
Q59120818TACROLIMUS (FK506)-ITS EFFECTS ON INTESTINAL GLUCOSE TRANSPORT1
Q36085572TP53 codon 72 Arg/Arg polymorphism is associated with a higher risk for inflammatory bowel disease development.
Q35957791Targeted delivery, safety, and efficacy of oral enteric-coated formulations of budesonide
Q43904806The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting
Q33250647The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients
Q59120851The buried gastrostomy bumper syndrome: prevention and endoscopic approaches to removal
Q33997864The epidemiology of inflammatory bowel disease in Canada: a population-based study
Q51251490The incidence rate of colectomy for medically refractory ulcerative colitis has declined in parallel with increasing anti-TNF use: a time-trend study.
Q41454651The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection
Q59120962The physiology of adaptation to small bowel resection in the pig: An integrated study of morphological and functional changes
Q46805368The probiotic VSL#3 has anti-inflammatory effects and could reduce endoscopic recurrence after surgery for Crohn's disease
Q36653913The role of antibiotic and probiotic therapies in current and future management of inflammatory bowel disease.
Q36220431The role of enteric microflora in inflammatory bowel disease: human and animal studies with probiotics and prebiotics.
Q59120386The sensitivity and specificity of guaiac and immunochemical fecal occult blood tests for the detection of advanced colonic adenomas and cancer
Q34842148Treatment of active Crohn's disease with MLN0002, a humanized antibody to the alpha4beta7 integrin
Q46549276Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin
Q37800674Tumor necrosis factor-α monoclonal antibodies in the treatment of inflammatory bowel disease: clinical practice pharmacology
Q40709112Ulcerative Colitis Patients With Clostridium difficile are at Increased Risk of Death, Colectomy, and Postoperative Complications: A Population-Based Inception Cohort Study.
Q34833079Understanding why probiotic therapies can be effective in treating IBD.
Q46536231Urinary metabolic profiles of inflammatory bowel disease in interleukin-10 gene-deficient mice
Q59120549VSL#3 Probiotic-Mixture Induces Remission in Patients with Active Ulcerative Colitis
Q50253608Validation of a point-of-care desk top device to quantitate fecal calprotectin and distinguish inflammatory bowel disease from irritable bowel syndrome
Q51589497Vanadate treatment rapidly improves glucose transport and activates 6-phosphofructo-1-kinase in diabetic rat intestine.
Q34365574Vedolizumab as induction and maintenance therapy for Crohn's disease
Q59120480Vertebral Fractures and Role of Low Bone Mineral Density in Crohn’s Disease
Q26823927Vitamin D improves inflammatory bowel disease outcomes: basic science and clinical review
Q55056247World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011.

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