Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis

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Caspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1039734334
P356DOI10.1038/SJ.CDD.4400837
P698PubMed publication ID11423910
P5875ResearchGate publication ID11916451

P50authorDirk GörlichQ30528426
P2093author name stringNicotera P
Ferrando-May E
Cordes V
Biller-Ckovric I
Mirkovic J
P2860cites workMolecular characterization of mitochondrial apoptosis-inducing factorQ22001452
Molecular segments of protein Tpr that confer nuclear targeting and association with the nuclear pore complexQ22008049
Functional analysis of Tpr: identification of nuclear pore complex association and nuclear localization domains and a role in mRNA exportQ22008581
Acinus is a caspase-3-activated protein required for apoptotic chromatin condensationQ22010542
Transport between the cell nucleus and the cytoplasmQ22065411
Nuclear envelope permeabilityQ22122423
A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complexQ24310068
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1Q24311327
Export of importin alpha from the nucleus is mediated by a specific nuclear transport factorQ24316152
A giant nucleopore protein that binds Ran/TC4Q24317506
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2Q24317523
Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filamentsQ24318735
Sequence and characterization of cytoplasmic nuclear protein import factor p97Q24318868
The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasmQ24323627
Sequence analysis of a cDNA encoding a human nuclear pore complex protein, hnup153Q24324042
The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNAQ24339283
Caspases: the executioners of apoptosisQ24530218
The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosisQ24532811
The novel SAR-binding domain of scaffold attachment factor A (SAF-A) is a target in apoptotic nuclear breakdown.Q24532883
DEDD, a novel death effector domain-containing protein, targeted to the nucleolusQ24533347
Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domainQ24534076
Activation of caspase-1 in the nucleus requires nuclear translocation of pro-caspase-1 mediated by its prodomainQ41011097
Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosisQ41115305
Inhibition of human caspases by peptide-based and macromolecular inhibitorsQ42538024
Suppression of actinomycin D-induced apoptosis by the NS3 protein of hepatitis C virusQ42806003
Regulation of nuclear transport in proliferating and quiescent cellsQ42811279
Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomainQ42826567
Separate nuclear import pathways converge on the nucleoporin Nup153 and can be dissected with dominant-negative inhibitorsQ44792760
Diffusion across the nuclear envelope inhibited by depletion of the nuclear Ca2+ store.Q49028313
Interleukin-1 beta converting enzyme.Q55065365
Essential role of active nuclear transport in apoptosisQ73251599
Selective proteolysis of the nuclear replication factor MCM3 in apoptosisQ74213891
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusionQ77089411
RanGAP1 induces GTPase activity of nuclear Ras-related RanQ24564044
The nucleoporin nup153 plays a critical role in multiple types of nuclear exportQ24641817
RanGTP-mediated nuclear export of karyopherin alpha involves its interaction with the nucleoporin Nup153Q24644181
RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complexQ24649249
Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteinsQ24671748
Major binding sites for the nuclear import receptor are the internal nucleoporin Nup153 and the adjacent nuclear filament protein TprQ24683280
Identification of NRF2, a member of the NF-E2 family of transcription factors, as a substrate for caspase-3(-like) proteasesQ28145527
Isolation of a protein that is essential for the first step of nuclear protein importQ28243173
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICADQ28258328
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleusQ28276214
Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich regionQ28566768
A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasmQ28582932
Identification and characterization of a nuclear pore complex proteinQ29616069
Cell death: the significance of apoptosisQ29617620
Distinct functions for the two importin subunits in nuclear protein importQ29620112
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic executionQ33882237
RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicaseQ33959492
Functional domains in nuclear import factor p97 for binding the nuclear localization sequence receptor and the nuclear poreQ34669894
An octamer of histones in chromatin and free in solutionQ35083833
RanBP2 associates with Ubc9p and a modified form of RanGAP1Q36105014
The permeability of the nuclear envelope in dividing and nondividing cell culturesQ36223246
In vivo analysis of the stability and transport of nuclear poly(A)+ RNA.Q36234469
Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinaseQ36234491
Interactions and three-dimensional localization of a group of nuclear pore complex proteinsQ36234494
Constitutive expression of the machinery for programmed cell deathQ36236957
Targeting and function in mRNA export of nuclear pore complex protein Nup153.Q36237348
Intranuclear filaments containing a nuclear pore complex protein.Q36534793
Splicing is required for rapid and efficient mRNA export in metazoansQ36776804
Direct and indirect association of the small GTPase ran with nuclear pore proteins and soluble transport factors: studies in Xenopus laevis egg extracts.Q37382182
Lymphocyte activation induces rapid changes in nuclear and cytoplasmic glycoproteinsQ37413972
RNA exportQ40400161
P433issue5
P304page(s)495-505
P577publication date2001-05-01
P1433published inCell Death & DifferentiationQ2943974
P1476titleCaspases mediate nucleoporin cleavage, but not early redistribution of nuclear transport factors and modulation of nuclear permeability in apoptosis
P478volume8

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