Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function

scientific article published in September 2001

Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021599384
P356DOI10.1038/SJ.ONC.1204679
P698PubMed publication ID11571655
P5875ResearchGate publication ID11775934

P50authorByrappa VenkateshQ28914672
Catherine J. PallenQ42859967
P2093author name stringS Brenner
F R Jirik
A Tay
Y H Tan
W P Yu
P2860cites workMutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouseQ22003952
The lipid phosphatase activity of PTEN is critical for its tumor supressor functionQ22007981
Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19Q22009077
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal regionQ22010498
Phosphorylation of the PTEN tail regulates protein stability and functionQ22254305
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphateQ24317714
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeastQ24336385
Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphataseQ24530579
Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivoQ24551809
A member of a family of sulfate-activating enzymes causes murine brachymorphismQ24680545
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane associationQ27620298
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Genomic organization of the mouse and human genes encoding the ATP sulfurylase/adenosine 5'-phosphosulfate kinase isoform SK2Q28115973
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancersQ28145813
Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphataseQ28188457
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersQ28306997
Pten is essential for embryonic development and tumour suppressionQ28509238
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTENQ28513537
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systemsQ28586004
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndromeQ29615538
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathwayQ29616144
Molecular cloning of a novel human PAPS synthetase which is differentially expressed in metastatic and non-metastatic colon carcinoma cellsQ30632705
The multiple roles of PTEN in tumor suppressionQ33849727
Fugu: a compact vertebrate reference genomeQ33957062
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndromeQ34504165
Databases on transcriptional regulation: TRANSFAC, TRRD and COMPELQ34650759
Epigenetic PTEN silencing in malignant melanomas without PTEN mutationQ35745799
Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qterQ35787692
Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma.Q36618853
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genomeQ36754912
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domainQ36818855
Absence of germline mutations in MINPP1, a phosphatase encoding gene centromeric of PTEN, in patients with Cowden and Bannayan-Riley-Ruvalcaba syndrome without germline PTEN mutationsQ43075717
Germline mutations in PTEN are present in Bannayan-Zonana syndromeQ48046915
Identification and characterization of a unique chondrocyte gene involved in transition to hypertrophyQ48062222
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in miceQ58378937
Impaired Fas response and autoimmunity in Pten+/- miceQ73019160
Analysis of PTEN and the 10q23 region in primary prostate carcinomasQ74531155
Regulation of dauer larva development in Caenorhabditis elegans by daf-18, a homologue of the tumour suppressor PTENQ77342895
PTEN mutations in endometrial cancers with 10q LOH: additional evidence for the involvement of multiple tumor suppressorsQ77789624
P433issue39
P407language of work or nameEnglishQ1860
P304page(s)5554-5561
P577publication date2001-09-01
P1433published inOncogeneQ1568657
P1476titleConserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function
P478volume20

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cites work (P2860)
Q40899888A Fugu-Human Genome Synteny Viewer: web software for graphical display and annotation reports of synteny between Fugu genomic sequence and human genes
Q44714783Compact intergenic regions of the pufferfish genome facilitate isolation of gene promoters: characterization of Fugu 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (fPapss2) gene promoter function in transgenic Xenopus
Q30816662Data mining the p53 pathway in the Fugu genome: evidence for strong conservation of the apoptotic pathway
Q24561882Genome duplication, a trait shared by 22000 species of ray-finned fish
Q44158956Identification and analysis of additional copies of the platelet-derived growth factor receptor and colony stimulating factor 1 receptor genes in fugu
Q33522318Statistical method on nonrandom clustering with application to somatic mutations in cancer
Q74093901The immunological synapse
Q44574619The regulation of retina specific expression of rhodopsin gene in vertebrates

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