Bacterial peptidoglycan-associated lipoprotein is released into the bloodstream in gram-negative sepsis and causes inflammation and death in mice

scientific article

Bacterial peptidoglycan-associated lipoprotein is released into the bloodstream in gram-negative sepsis and causes inflammation and death in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M109696200
P698PubMed publication ID11830585
P5875ResearchGate publication ID11529292

P2093author name stringJudith Hellman
H Shaw Warren
Jesse D Roberts
Jennifer E Allaire
Megan M Tehan
P2860cites workHost defense mechanisms triggered by microbial lipoproteins through toll-like receptorsQ22010442
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2Q22010443
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 GeneQ22299417
A Toll-like receptor recognizes bacterial DNAQ24290668
Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptorsQ24669767
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxinQ28306447
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2Q28646106
NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxideQ33575382
The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failureQ33838051
Galactosamine-induced sensitization to the lethal effects of endotoxinQ33983065
Shock and tissue injury induced by recombinant human cachectinQ34189904
The Pseudomonas putida peptidoglycan-associated outer membrane lipoprotein is involved in maintenance of the integrity of the cell cell envelope.Q35604067
Characterization of the tol-pal region of Escherichia coli K-12: translational control of tolR expression by TolQ and identification of a new open reading frame downstream of pal encoding a periplasmic proteinQ35609184
Gram-Negative Sepsis and the Adult Respiratory Distress SyndromeQ36288807
Septic shock: pathogenesisQ36518501
Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentrationQ36862967
The pathogenesis of sepsisQ37251283
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapyQ37943123
Outer membrane protein A, peptidoglycan-associated lipoprotein, and murein lipoprotein are released by Escherichia coli bacteria into serumQ39515501
A Novel Peptidoglycan-Associated Lipoprotein Found in the Cell Envelope of Pseudomonas aeruginosa and Escherichia coliQ39694390
Sepsis and septic shock--a review of laboratory models and a proposalQ40290200
Scrub typhus-associated hemophagocytic syndromeQ40619047
Epidemiology of sepsis syndrome in 8 academic medical centersQ40647998
Isolation of outer membranesQ40687412
Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responsesQ40822144
Mechanisms of endotoxin shock and endotoxin hypersensitivityQ40825133
Nitric oxide in sepsis and endotoxaemiaQ40866096
Mechanism of gram-positive shock: identification of peptidoglycan and lipoteichoic acid moieties essential in the induction of nitric oxide synthase, shock, and multiple organ failureQ41024121
The lipoprotein of the outer membrane of Escherichia coli: a B-lymphocyte mitogenQ41773386
The excC gene of Escherichia coli K-12 required for cell envelope integrity encodes the peptidoglycan-associated lipoprotein (PAL).Q42610591
Treatment of gram-negative bacteremia and shock with human antiserum to a mutant Escherichia coliQ44505327
TolB protein of Escherichia coli K-12 interacts with the outer membrane peptidoglycan-associated proteins Pal, Lpp and OmpA.Q47694282
Nucleotide sequence of the gene for the peptidoglycan-associated lipoprotein of Escherichia coli K12.Q48349323
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunctionQ50117610
Antibodies to Core Lipopolysaccharide Determinants: Absence of Cross-reactivity with Heterologous LipopolysaccharidesQ50188669
Nitric oxide inhalation decreases pulmonary artery remodeling in the injured lungs of rat pups.Q51390852
Antiserum against Escherichia coli J5 contains antibodies reactive with outer membrane proteins of heterologous gram-negative bacteria.Q51534401
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectlipoproteinQ28350
inflammationQ101991
sepsisQ183134
Gram-negative bacteriaQ632006
P304page(s)14274-14280
P577publication date2002-02-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleBacterial peptidoglycan-associated lipoprotein is released into the bloodstream in gram-negative sepsis and causes inflammation and death in mice
P478volume277

Reverse relations

cites work (P2860)
Q30156997A modular BAM complex in the outer membrane of the alpha-proteobacterium Caulobacter crescentus.
Q48540868Activation of Toll-like receptor 2 impairs hypoxic pulmonary vasoconstriction in mice.
Q36240198Activation of endothelial TLR2 by bacterial lipoprotein upregulates proteins specific for the neutrophil response
Q36351797Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo
Q42272803Burkholderia cenocepacia differential gene expression during host-pathogen interactions and adaptation to the host environment
Q36448221Cloning, purification and preliminary X-ray crystallographic analysis of the OmpA-like domain of peptidoglycan-associated lipoprotein from Acinetobacter baumannii
Q49792103Complete genome sequencing of Acinetobacter baumannii str. K50 disclosed the large conjugative plasmid pK50a encoding the carbapenemase OXA-23 and the extended-spectrum β-lactamase GES-11.
Q44753772Conditioned taste aversion with lipopolysaccharide and peptidoglycan does not activate cytokine gene expression in the spleen and hypothalamus of mice.
Q35357091Cysteinyl leukotrienes impair hypoxic pulmonary vasoconstriction in endotoxemic mice
Q38742627Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli
Q41929627Dual orientation of the outer membrane lipoprotein Pal in Escherichia coli.
Q35093114Endogenous versus exogenous glucocorticoid responses to experimental bacterial sepsis
Q38897447Endotoxemia-menace, marker, or mistake?
Q37304848Hemopexin down-regulates LPS-induced proinflammatory cytokines from macrophages
Q35929055Inhaled hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice.
Q47648843Interferon-β Improves Sepsis-related Alveolar Macrophage Dysfunction and Post-septic ARDS-related Mortality.
Q57158084Interplay between Peptidoglycan Biology and Virulence in Gram-Negative Pathogens
Q47869158Klebsiella pneumoniae peptidoglycan-associated lipoprotein and murein lipoprotein contribute to serum resistance, antiphagocytosis, and proinflammatory cytokine stimulation
Q37411194Legionella lipoprotein activates toll-like receptor 2 and induces cytokine production and expression of costimulatory molecules in peritoneal macrophages
Q47227261Lipopeptide Pam3Cys4 Synergizes N-Formyl-Met-Leu-Phe (Fmlp)-Induced Calcium Transients in Mouse Neutrophils.
Q36845213Outer membrane antigens of the uropathogen Proteus mirabilis recognized by the humoral response during experimental murine urinary tract infection
Q35586916Passive immunization to outer membrane proteins MLP and PAL does not protect mice from sepsis.
Q55034091Peptidoglycan-associated lipoprotein of Aggregatibacter actinomycetemcomitans induces apoptosis and production of proinflammatory cytokines via TLR2 in murine macrophages RAW 264.7 in vitro.
Q41628599Proteomic analysis of Lawsonia intracellularis reveals expression of outer membrane proteins during infection.
Q24654161Resilience to bacterial infection: difference between species could be due to proteins in serum
Q35801874Role of Toll-like receptor 4 in macrophage activation and tolerance during Salmonella enterica serovar Typhimurium infection
Q99616786Roles of the Tol-Pal system in the Type III secretion system and flagella-mediated virulence in enterohemorrhagic Escherichia coli
Q33693897Serum lipoproteins attenuate macrophage activation and Toll-Like Receptor stimulation by bacterial lipoproteins
Q36788696Stress molecules in sepsis and systemic inflammatory response syndrome
Q30449521Suppression of serum antibody responses by pertussis toxin after respiratory tract colonization by Bordetella pertussis and identification of an immunodominant lipoprotein
Q40436122The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation
Q59798239The Outer Membrane Vesicles of ATCC 7966: A Proteomic Analysis and Effect on Host Cells
Q92921740The Tol-Pal System of Uropathogenic Escherichia coli Is Responsible for Optimal Internalization Into and Aggregation Within Bladder Epithelial Cells, Colonization of the Urinary Tract of Mice, and Bacterial Motility
Q40906335The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn.
Q28750494The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes
Q34759935The two murein lipoproteins of Salmonella enterica serovar Typhimurium contribute to the virulence of the organism
Q64259221Transcriptomic Analysis of Reveals Different Virulence Gene Expression in Response to Benzyl Isothiocyanate
Q37237086Trovafloxacin enhances the inflammatory response to a Gram-negative or a Gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice
Q33316838Vesicle-independent extracellular release of a proinflammatory outer membrane lipoprotein in free-soluble form
Q39028318Vibrio vulnificus IlpA-induced cytokine production is mediated by Toll-like receptor 2.
Q37372289Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis.
Q34339870Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus

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